!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Methylprednisolone
!smiles	CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)CO)O
!drugbank_id	DB00959
!pubchem_cid	6741
!cell_type	Skeletal muscle - 7 Hour
!organism	rat
!end_metadata
GLUL	0.333085
MGP	0.256207
PDK4	0.189538
HP	0.175134
TRIM54	0.156156
TRIM63	0.150074
TSC22D1	0.145493
RHOB	0.143775
HSPB1	0.140222
MYF6	0.139052
KLF9	0.120841
EIF4EBP1	0.105124
LYZ	0.104892
ACTG1	-0.104016
MYL2	-0.101099
ACTN2	0.097145
LCN2	0.095874
ND1	0.094618
XDH	0.093009
CST3	0.091973
TUBA1A	-0.091172
CEBPB	0.090535
NR4A1	0.090005
CTSV	0.088357
CXCL2	0.081645
AMPD1	-0.079450
CTSS	0.079008
ATP5B	0.077846
ACTB	-0.077418
DYNLL1	-0.076572
TCAP	0.076525
MAPK14	0.075498
ACTC1	0.073129
TNNT3	-0.072603
TUBA1B	-0.071756
MYBPC1	0.071638
HPX	0.070661
ERRFI1	0.068747
CSRP3	0.068400
MYL12B	-0.067755
PSME4	0.067040
CKM	0.065965
RPL3L	-0.065730
NEU2	-0.064543
LDHB	-0.063979
CACNG1	-0.063095
ASB2	-0.062967
ATP5H	-0.061562
NDUFS7	0.061340
DDX3X	0.060968
FABP4	0.060927
IL6	0.060619
PCBP4	0.060059
MAP1LC3B	0.057555
CA3	-0.056652
B2M	0.056128
LUM	-0.056106
CD36	0.053995
ZFP36	0.053914
ATP2A1	0.053479
AQP1	0.053055
NDUFA4	-0.052663
AK1	-0.052400
CYC1	-0.052236
CKMT2	0.052222
PPP1CA	-0.052211
FXYD1	-0.052127
HSPA8	-0.051976
SLC16A3	-0.050359
RPS29	-0.049920
TECR	-0.049513
TMA7	-0.048482
NDUFB2	-0.048377
ENO3	-0.048187
MORF4L2	-0.047831
KLHDC3	0.047689
PPIA	-0.047523
AKR1A1	-0.047181
KNG1	0.047051
SVIL	0.046257
CCL13	0.046066
MYADM	-0.045615
ND4	-0.045329
NFKBIA	0.045198
PYGM	0.045135
FABP3	0.044729
OAZ1	-0.044259
LGALS1	-0.043766
CLU	0.043340
MYH2	0.043300
SERPINH1	-0.043188
SPP1	0.042248
RPL7A	-0.041992
MYH7	0.041851
SLC2A4	0.041363
CBFB	-0.041323
VDAC1	-0.040941
LGALS3	0.040664
TPT1	0.040623
BIN1	-0.040420
SDC4	0.040191
COX3	-0.039436
CHRNA1	-0.039195
KLHL41	-0.039130
COX4I1	-0.038824
MYL1	0.038400
NDUFC1	-0.037995
PKM	0.037885
RPL8	-0.037799
IDH2	-0.037669
LPL	0.037584
HSP90AB1	-0.037580
CD81	-0.037402
PSMB5	-0.037355
MYL3	0.037334
ACTA1	0.037308
ATP5G2	-0.037223
RPS25	-0.037203
CRYAB	-0.036941
ACADM	0.036823
COX7B	-0.036818
PKIA	-0.036116
GPX1	-0.035606
PTPN3	-0.035526
MMP14	-0.035387
YWHAH	0.035347
ATP5A1	0.035050
YBX3	0.034913
CEBPD	0.034740
POMP	-0.034617
PLAU	0.034598
C1QB	0.034563
GAA	-0.034322
GSTP1	-0.034321
CD63	-0.034213
COL1A2	-0.034040
FGG	0.034030
FGA	0.034015
SGK1	0.033752
SCHIP1	0.033702
NDUFV2	0.033438
PTP4A2	-0.033282
FLNC	0.032955
MDH2	0.032901
COX5A	0.032874
SLC28A2	0.032852
MAPK6	-0.032712
CITED2	-0.032669
DNAJB5	0.032539
SLC25A5	0.032284
GPX3	0.032251
RPS17	-0.032052
SLC25A4	0.032004
CCNG1	0.031984
TUBA4A	-0.031726
FTH1	0.031519
RPS27L	-0.031308
CACNA2D1	-0.031123
WIPF3	0.030980
NDUFB6	-0.030936
ARF1	-0.030820
H2AFZ	-0.030749
RPS12	0.030514
ANXA5	-0.030476
LYVE1	0.030267
HNRNPK	-0.030225
PDK2	-0.029659
SERPINE1	0.029584
PSMD2	-0.029555
ALB	0.029522
LOX	0.029456
ITM2B	-0.029442
RPL22	-0.029111
SNRPB	-0.029006
EMP1	-0.028870
CFB	0.028793
RPL26	-0.028772
IDH3G	0.028731
RPL17	0.028692
ACAA2	0.028439
MGST2	0.028295
MDH1	0.028275
RAB5B	-0.028264
APOE	0.028248
TIMP1	0.027931
FSTL1	-0.027911
GRINA	0.027788
RPL27	-0.027568
NEXN	-0.027525
LOXL1	-0.027523
LDB3	0.027227
BTG2	0.027008
CAPG	0.026920
NDRG2	0.026908
TNNI1	-0.026881
FTL	-0.026792
ND2	-0.026788
SIRT2	-0.026783
TMEM59	-0.026676
SEPW1	-0.026640
PDHA1	0.026495
COX6A2	-0.026492
PGM2	-0.026460
SOD1	-0.026236
TNNC2	0.026152
SLC37A4	-0.026061
ALDOA	0.025955
TXNIP	0.025733
FAU	-0.025702
UBE2G2	0.025688
SERBP1	-0.025672
RPS16	-0.025671
NEK7	-0.025669
PSMC3	-0.025637
CYTB	-0.025438
PHKG1	-0.025327
NDUFB3	-0.025223
RPL9	-0.025212
COL5A2	0.025181
PSMB6	-0.025083
JUNB	0.024986
PTP4A1	-0.024919
RAF1	-0.024878
RHEB	0.024539
COL3A1	0.024377
SCN1B	-0.024305
PFKFB4	0.024240
ECE1	0.024111
CHRNB1	-0.024009
CASQ1	-0.023919
ANKRD1	0.023787
VIM	0.023766
CAPNS1	-0.023764
RPS15	-0.023673
SDHAF2	-0.023558
CYB5R1	-0.023557
C3	0.023536
NDUFV3	0.023529
RPS6	0.023516
PITPNA	-0.023358
NR1D1	-0.023323
MYBPH	-0.023285
TSPO	0.023274
RAB10	-0.023243
GPD1	-0.023169
RPL10	-0.023079
UQCRC2	-0.023073
GNB2L1	-0.022811
MPC1	-0.022677
TUBA1C	0.022599
COX1	0.022386
MFGE8	-0.022322
SPARC	-0.022180
CAPN3	-0.022169
ATP5G1	-0.022154
BTG1	0.022072
CXXC5	-0.022016
SERPINA3	0.022000
NDUFA3	-0.021941
ATP5F1	-0.021892
CAP2	-0.021853
BSG	0.021664
CPA1	-0.021658
NPHP1	-0.021642
VEZF1	-0.021398
ATP1A2	0.021324
PPP3CA	-0.021282
CYP27A1	0.021240
HIGD2A	-0.021163
RPS15A	-0.021065
PARK7	-0.021021
NUDT4	-0.020858
KCNC4	-0.020742
PGAM1	0.020576
PIM3	0.020550
MYH1	0.020474
GPX4	-0.020432
ECH1	0.020391
CTBP1	-0.020367
TCEB1	-0.020322
IGF2	-0.020314
TIMM17A	-0.020214
JPH2	-0.020174
IRS1	-0.020171
PECAM1	0.020171
GADD45A	0.020161
NRP1	-0.020109
TIMP2	0.020031
ANXA2	-0.019999
TRAPPC1	-0.019921
PDHB	-0.019765
HADHA	-0.019742
ARL4A	0.019716
LAMC1	0.019586
MLLT3	-0.019543
PPP2R1A	-0.019465
PPARD	0.019450
SDC2	-0.019447
PEBP1	-0.019415
GPD2	-0.019398
ATP1B1	-0.019332
PLA1A	0.019262
S100A10	0.019196
CXCL14	-0.019184
RPL28	-0.019179
SPRY1	0.019158
VEGFA	0.019098
CDC37	-0.019075
DES	0.018996
STAT5B	-0.018942
MRPL45	0.018877
CLTC	-0.018872
COX8A	-0.018801
YWHAG	-0.018736
PSME1	-0.018664
NDUFA8	0.018539
DYNLRB1	-0.018533
ACSL6	-0.018532
ATP1B3	-0.018464
CD151	-0.018447
APRT	-0.018328
LITAF	0.018152
AHNAK	0.018119
GC	0.018104
RRAD	0.018060
PRNP	-0.018011
DAD1	-0.017910
CLCN1	-0.017901
CAV3	-0.017780
LMNA	-0.017769
INSIG1	0.017665
RPL23	0.017628
PRKAR1A	-0.017615
PVALB	-0.017612
H19	0.017379
COX6A1	-0.017369
BECN1	-0.017260
MAP1LC3A	0.017255
RPS10	-0.017201
PHB2	-0.017143
RPL13A	-0.017103
NFIX	-0.017060
MYL9	-0.017049
SLC41A3	-0.016869
BCL2L1	0.016867
RBBP7	-0.016822
CUL2	-0.016790
TNS1	0.016588
SUB1	-0.016574
TUFM	0.016544
EEF1G	-0.016509
ITGB1	-0.016419
RPL15	0.016276
TTR	0.016252
ACSL1	-0.016178
SEPP1	0.016126
AP2M1	-0.016119
PRDX2	-0.016098
S100A8	0.015938
HSPE1	-0.015934
SDCBP	0.015915
TSPAN8	0.015850
RPL39	-0.015724
FABP6	-0.015717
PSMB4	-0.015661
BHLHE40	-0.015628
F2R	-0.015593
MYBPC2	-0.015547
TSPAN3	-0.015545
CSRP2	0.015543
NUTF2	-0.015507
ECHS1	-0.015458
HBP1	0.015422
BLMH	-0.015321
PPP2CA	0.015313
BNIP3L	0.015311
AMPD3	0.015225
CDO1	0.015144
RPL4	-0.015143
DAPK2	-0.015024
HSPD1	-0.015007
CCL20	0.015007
TJP1	-0.014978
COA5	-0.014962
SMPX	-0.014952
BCAT2	-0.014894
SLC3A2	0.014707
ANXA6	-0.014623
OXR1	-0.014593
NEDD8	-0.014529
PHKA1	-0.014473
SMARCD2	0.014462
ACADL	-0.014456
NDUFS8	-0.014407
CYCS	-0.014375
PSMB2	-0.014350
MYH6	0.014335
ANGPT2	0.014328
DCAKD	-0.014320
EIF2S3	-0.014301
KCNJ11	-0.014262
TOMM20	-0.014248
MYL12A	-0.014248
DNPEP	-0.014247
NRARP	-0.014235
RPS3	-0.014193
KLC1	0.014169
ITIH4	0.014121
NDUFB5	-0.014082
HNRNPF	0.014079
LTBP1	-0.014073
P4HA1	-0.014034
CCND2	-0.014002
OAT	0.013999
ATP9B	-0.013979
DNM1	-0.013975
RPL11	-0.013861
SLC6A6	0.013855
PPP1R1A	-0.013771
SCARB1	-0.013752
RHOJ	0.013718
MGST3	0.013673
RGCC	0.013663
MGST1	0.013573
NAA15	-0.013534
UQCR11	-0.013518
CTSD	0.013511
PRKACA	-0.013491
EEF2K	0.013409
DECR1	-0.013408
EIF3D	0.013378
PLEC	0.013373
HK2	0.013354
PAPSS1	-0.013332
CREG1	0.013225
SNN	-0.013151
RPS4Y1	-0.013143
CAPN6	-0.013131
SOD2	0.013084
FKBP1A	-0.013078
RPL35	0.013066
CTSB	0.013060
EIF2B4	0.013046
NME2	0.013036
MAFK	0.012954
SH2B3	0.012918
RPS23	-0.012899
PTK2	-0.012816
SHFM1	-0.012771
H1F0	-0.012761
ENO1	0.012758
COX7A2	0.012673
FMO1	0.012664
GNPAT	0.012644
FDFT1	-0.012600
MYLK2	-0.012592
RAB6A	-0.012582
IFRD1	0.012534
COL15A1	-0.012477
TOR1AIP1	0.012472
PGK1	-0.012458
CXCL10	0.012426
CDK4	-0.012407
POLR2F	-0.012405
AKAP12	-0.012391
SELP	0.012340
CRTAP	-0.012314
IGFBP6	0.012312
RHOC	-0.012300
MED25	0.012259
RPS14	0.012255
TMBIM6	-0.012239
UCP2	0.012207
P2RY2	-0.012176
PTPN1	0.012116
PGAM2	-0.012096
HOMER1	-0.012069
ACTA2	-0.012068
IGF2R	-0.012028
CHURC1	-0.012027
CPE	-0.012014
TNFRSF21	-0.011961
RRAGA	0.011891
GNB2	-0.011833
CAPN1	-0.011822
NCOA4	0.011814
DHRS7C	-0.011775
IGFBP5	-0.011744
ACAT1	-0.011735
AHSG	0.011710
APLP2	-0.011709
CRISPLD2	0.011707
GOT1	0.011692
CYP4B1	0.011688
POSTN	-0.011680
ATP6AP1	-0.011665
LTA4H	-0.011607
CPS1	0.011602
CD48	-0.011595
YWHAB	-0.011578