!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Methylprednisolone
!smiles	CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)CO)O
!drugbank_id	DB00959
!pubchem_cid	6741
!cell_type	Skeletal muscle - 1 Hour
!organism	rat
!end_metadata
COX2	-0.269381
NFKBIA	0.207330
RHOB	0.184477
ZFP36	0.159917
NDUFB9	-0.159684
PDK4	0.159314
UCP3	0.153703
NDUFS7	0.148424
HSPB6	-0.148118
CLU	0.147873
NDUFV2	0.124255
MGP	0.121877
ACADM	0.119146
MDH1	0.112772
RRAD	0.110722
CYTB	-0.108223
ACTN2	0.106078
ALDH1A1	0.105792
CEBPB	0.101922
CA3	0.101130
PKM	0.100918
MYBPC1	0.094938
CKM	-0.092717
MDH2	0.092636
PVALB	0.091688
PYGM	0.089390
ACTG1	-0.087284
ASB2	0.085446
TNNC2	0.082426
MPC1	0.080197
PPP2R5A	0.079854
LDHA	0.079181
COL3A1	-0.078860
ERRFI1	0.078856
CYCS	-0.078410
HSP90AB1	0.077163
ND4	-0.076602
NDUFB2	0.075571
MYBPC2	0.075138
TXNIP	0.074786
UQCR11	0.074284
ATP5O	0.074105
CHRNA1	-0.073890
GLUL	0.072095
NR4A1	0.071250
TNNT3	-0.070395
COX6A2	0.069941
MYL2	-0.069008
ACTC1	-0.068313
NME2	0.067854
ACAA2	-0.067662
COX7A2	-0.067486
PABPC4	0.067481
TRIM63	0.067437
PTP4A2	0.065504
UQCRFS1	0.064645
TSC22D1	0.063794
TPI1	0.063442
ATP5H	-0.062982
COL1A2	0.061364
EIF4A2	0.061077
IDH2	0.060867
CSRP3	-0.059073
ATP5B	0.058071
RPL10	0.057712
TIMP2	0.056632
PMP22	0.055286
RPS26	-0.052845
RPS27L	-0.052786
RPL17	0.052458
NDUFB3	-0.052406
ACADL	-0.052257
COX5A	0.051714
LGALS1	-0.051481
AKR1A1	0.051113
JUN	-0.050639
GOT1	0.050491
AUH	0.048459
CXCL2	0.048283
SGK1	0.048118
RPL26	-0.047820
CCNG1	0.047037
JPH2	0.047003
FTL	-0.046933
ND5	0.046112
SLC25A4	0.045465
HSPA8	-0.044739
ACTA1	-0.044653
RPL22	0.044603
POSTN	-0.044600
TPT1	-0.043855
SLC41A3	0.043697
KLF9	0.043341
COL1A1	0.043036
ATP5J	0.042893
EEF1G	-0.042849
PSAP	0.042806
CAPZA2	-0.042502
CTSV	-0.042448
HSPB1	-0.042343
CBFB	-0.041753
RPL39	-0.041467
ZFP36L1	-0.041247
NAPA	0.041218
COX1	-0.041168
SERPINH1	0.041105
PPIA	-0.041044
FLNC	-0.041003
CEBPD	0.040287
BSG	0.039910
CST3	0.039842
ATP6	-0.039632
MYL4	-0.039604
MYF6	-0.039581
GPX4	0.039502
COX8A	-0.039148
IFITM3	0.039015
MGST3	0.038807
MYL12B	-0.037366
DNAJA4	0.037009
RPS25	-0.036834
RPSA	-0.036565
TNNI2	0.036496
PTP4A1	-0.035901
CKMT2	0.035825
DNAJB5	0.035819
CACNA1S	0.035811
NEU2	0.035721
SEPW1	0.035651
MYL3	0.035437
RPL3L	0.035299
EEF2	0.034899
NR1D1	-0.034676
PHKA1	0.034572
G0S2	-0.034448
DCAF6	0.034446
NDUFA3	0.034316
CAP2	0.033692
ID3	-0.033688
TNNI1	-0.033655
FOS	-0.033486
DYNLL1	-0.033399
SMPX	-0.033378
ATP1A2	0.033130
PDHA1	0.033129
PPIF	-0.033010
TUFM	0.032819
DNAJA1	-0.032713
RPS16	0.032680
SLC16A3	0.032680
NDUFA8	0.032296
RAB10	-0.032203
MYH6	0.032173
NDUFB6	-0.032101
PADI2	0.031932
ACKR3	0.031712
KLHL41	-0.031653
VDAC1	0.031599
TUBA1B	-0.031510
LUM	-0.031138
FMOD	0.030908
DBP	-0.030710
AQP1	0.030591
CITED2	-0.030195
CDC42EP3	0.030140
ENO1	-0.030062
ATP2A1	0.029700
CISH	0.029696
PSMD2	-0.029267
MORF4L2	0.029254
JUNB	0.029242
TMA7	-0.029028
HRAS	-0.028840
MPZ	0.028487
H19	0.028167
CASQ1	-0.028085
TIMM23	-0.028021
IDH3G	0.028020
APOE	-0.027890
SLC25A11	0.027705
FTH1	0.027527
VEGFA	0.027523
IL6	0.027253
RPL23	0.027196
ND1	-0.027160
SLC37A4	0.027092
GAPDH	0.027091
RPL27	-0.027084
PHKG1	0.026683
XDH	0.026131
SERBP1	-0.026122
RPL7A	0.026044
MMP14	-0.025989
TMOD1	0.025969
NPHP1	0.025413
RPS12	-0.025077
RPL9	-0.024967
CHAD	0.024946
NDUFB8	0.024749
VCP	0.024727
SDHA	-0.024609
MYBPH	-0.024326
NDRG2	-0.024317
YBX3	0.024167
ANKRD1	-0.024077
OAZ1	0.023919
ATP6V0C	0.023858
ATP5A1	0.023805
TCAP	0.023719
ATP1B3	-0.023708
ATP6V1F	-0.023514
ALDOA	-0.023473
ORAI1	-0.023455
PFKM	0.023361
ADM	0.023360
YBX1	0.023225
PECAM1	0.023081
GNAS	0.023046
PPP3CA	0.023039
DUSP1	-0.022970
MYOG	-0.022814
NRARP	-0.022709
MYH2	0.022449
GPX1	-0.022338
CYC1	-0.022290
RPLP0	0.022198
MYLPF	0.022195
ZFAND6	-0.022029
NDUFB10	0.021950
PSME4	-0.021897
AES	0.021875
TRAPPC6B	0.021842
AK3	0.021706
HIGD2A	0.021702
UQCC2	0.021694
GRB10	-0.021691
SNRPN	0.021489
BIN1	0.021465
SPARC	0.021355
NEK7	0.021331
EFNA1	-0.021121
DCN	0.021047
SCN1B	0.021000
PPP1R2	0.020943
CTBP1	0.020918
RABAC1	0.020892
MYLK2	-0.020874
ACSL6	0.020845
NUDT4	-0.020745
FIS1	-0.020688
IGF2	0.020659
RPL8	-0.020633
GSTM2	0.020585
PSMB4	0.020413
PSME1	0.020362
GAS6	0.020272
MYADM	-0.020248
DACT2	-0.020223
DDR1	-0.020150
DAPK2	-0.020115
LDB3	-0.019972
RPS27A	-0.019954
SOD3	0.019904
PCOLCE	0.019827
NDUFB5	0.019669
RPL13A	-0.019436
ARL4A	0.019357
MAPKAPK3	0.019304
RPS23	-0.019286
PPP1R1A	0.019258
SLC2A4	-0.019231
PRDX2	0.019172
COX7A2L	-0.019151
PSME2	0.019138
SNRNP70	-0.019087
UBC	-0.019079
MAOA	0.019019
APH1A	-0.019012
S100A10	0.018912
PPP1CB	0.018907
TFRC	-0.018767
RPL4	-0.018500
SLC6A8	0.018458
STAT5B	-0.018310
MYOD1	-0.018291
PSMD4	-0.018247
PDK2	0.018140
GPD1	0.017994
RPL15	0.017966
ATP2A2	0.017917
HK2	0.017795
HUWE1	0.017776
NAGA	0.017771
RPS13	-0.017632
PSMD11	0.017565
AK1	0.017477
GRB14	0.017395
GABARAPL2	-0.017125
DDX3X	0.017121
CYTH2	-0.017094
MAP2K2	0.017000
RPS14	0.016991
KLF10	-0.016978
EEF1A2	0.016912
PHB2	-0.016910
B4GALT6	0.016807
HADHA	0.016727
RAB5B	-0.016712
TNFRSF21	-0.016649
NACA	-0.016576
TSPAN3	-0.016503
UBXN1	-0.016455
B2M	-0.016428
CPT1B	-0.016414
GSTM1	-0.016392
EGR1	-0.016265
LAMC1	0.016186
RPS9	0.016161
BLMH	-0.016154
RPS7	0.016149
FXYD1	-0.016144
UBR5	0.016125
CRYAB	-0.016104
CD151	-0.016008
SDC4	0.016000
ND2	0.015999
LITAF	0.015993
DLK1	-0.015871
PPP2CB	0.015840
ATP5G2	0.015758
KCNJ11	0.015741
LDHB	-0.015738
MYH1	0.015680
MYH8	-0.015645
P4HA1	0.015635
KIF13A	0.015503
FN3K	-0.015442
EIF4E2	-0.015430
OAT	0.015424
RPS17	-0.015363
HNRNPAB	0.015250
KLF6	-0.015232
EEF2K	0.015189
TRIM8	-0.015137
PFN1	-0.015027
SOCS3	0.015001
MAPK3	-0.014997
RGCC	0.014993
MYC	0.014974
H2AFZ	-0.014931
ATP1B1	-0.014918
CDC37	0.014908
PPP2R1A	-0.014906
MTDH	0.014892
CD55	0.014886
PLK1	-0.014879
MEOX2	-0.014873
NDUFS1	0.014853
CALU	-0.014834
HSPA9	-0.014809
PRKCDBP	0.014796
HNRNPF	0.014772
GNB2L1	0.014754
NEB	-0.014731
RPL19	-0.014712
PTOV1	0.014695
NUTF2	-0.014692
BTF3L4	-0.014620
NDUFA9	-0.014561
SLC3A2	0.014554
ATP5D	0.014450
KCNA5	0.014418
MAPKAPK2	0.014417
LAMTOR1	-0.014397
FOXS1	-0.014319
ARFGAP2	-0.014300
TCP11L2	-0.014285
VEGFB	0.014260
DDIT3	-0.014217
MRFAP1	0.014178
SCARB1	-0.014156
HDAC2	-0.014147
FAU	0.014116
SNCG	0.014111
RPS5	0.014033
CAMK2B	0.013974
CAV1	0.013933
TCN2	-0.013893
RPL10A	-0.013874
YWHAG	0.013810
UBE2G2	0.013774
ANGPT2	0.013712
AKAP12	0.013662
EIF4EBP1	0.013596
NFKB1	0.013591
TIMM17A	-0.013509
PJA2	0.013494
HES1	-0.013380
ENO3	0.013371
MAPK14	0.013336
RHOA	0.013299
SLC25A5	0.013287
PNRC2	-0.013285
MRPL52	-0.013281
PRX	0.013244
HADHB	0.013210
SCD	-0.013192
LYVE1	0.013170
RPS3	0.013158
CNN3	0.013144
CRP	-0.013136
COX6A1	-0.013134
PMEPA1	-0.013118
NDUFAB1	-0.013115
COX3	0.013086
CANX	-0.013069
KCNJ8	-0.013052
CXXC5	-0.013011
PRKACA	0.013000
NDUFB4	-0.012989
ST13	0.012978
SDHAF2	-0.012963
ATF3	-0.012937
ID1	-0.012846
COL15A1	0.012785
USE1	-0.012778
LBH	-0.012727
GIPC1	-0.012602
ATP1A1	0.012598
TXNRD1	0.012586
S100A8	0.012570
NFIX	0.012557
LAMB2	0.012537
MPST	0.012534
ALDH2	0.012514
C1QB	0.012435
CXCL10	0.012417
VIM	-0.012385
RPL3	-0.012375
RXRA	0.012288
HDLBP	0.012277
RPL24	-0.012216
PSMB6	0.012190
PAFAH1B1	0.012169
PRKAR1A	-0.012161
MGST2	0.012136
CSF1	-0.012120
PSMC1	-0.012120
TRIM54	-0.012086
PF4	-0.012085
H1F0	-0.012055
DLAT	0.012000
ACADVL	-0.011999
RPL21	-0.011990
GNB1	0.011951
GADD45A	0.011934
PDHB	-0.011929
ATP5F1	-0.011909
PSMC3	-0.011856
TUBB	-0.011853
SSR3	-0.011851
RARA	-0.011808
ICAM1	0.011783
RPS4Y1	0.011763
PSMA2	-0.011746
VPS52	0.011733
PRNP	0.011702
C11orf73	0.011701
GLUD1	0.011699
EIF5	0.011692
TMEM259	-0.011691
GSTO1	0.011657
CACNA2D1	-0.011619
SELP	0.011561
MAPK6	-0.011535
PSMB3	-0.011424
NR1D2	-0.011423
JTB	0.011375
MRPL3	0.011366
GNAI3	0.011360
CD81	-0.011348
TJP1	-0.011340
UBQLN1	0.011284
HSP90AA1	0.011256
TOMM20	-0.011246
MAP2K6	-0.011246
DDT	-0.011213
PPP1CA	-0.011195
PEX14	-0.011165
ZNRF1	0.011152
SPARCL1	0.011117
ATP5C1	0.011092
MRPL45	-0.011048
CTSS	0.011037
RUNX1	-0.010975
ARPC4	-0.010967
CXCL14	0.010962
EAF1	-0.010955
DYNLRB1	-0.010944
GFM1	0.010898