!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!ligand_name	17beta-estradiol
!ligand_id	CHEBI:16469
!cell_type	MCF-7 cells
!organism	human
!end_metadata
TFF1	0.220263
IFI44L	-0.175586
ISG15	-0.167206
DKK1	0.158759
HLA-B	-0.145901
IFITM1	-0.144931
IFI6	-0.142263
IFIT1	-0.134035
IFI44	-0.133769
HLA-A	-0.117796
HLA-C	-0.096147
RPS18	-0.095432
IGFBP3	-0.093414
COX1	0.091696
PABPC3	0.087682
LAPTM4A	0.087007
RPL36A	0.084950
B2M	-0.080857
IFITM3	-0.077857
TXNIP	-0.076432
HSPA8	0.075941
CMPK2	-0.074981
FAM214A	-0.073934
ID1	-0.072286
RSRP1	-0.069153
GPRC5A	0.068467
NACAP1	0.066981
OAS1	-0.066298
IFI30	-0.066035
FTL	-0.065039
RPS10	-0.064899
FXYD3	-0.061975
SAMD9	-0.061910
COX3	0.061245
XBP1	0.060919
HLA-G	-0.058913
S100A6	-0.057846
EIF3E	0.057818
SNHG5	0.056449
ATP6	0.056150
S100P	-0.055061
RPL13A	-0.054439
RPS5	0.054429
ADAR	-0.053815
LGALS3BP	-0.053479
HLA-E	-0.052794
INSIG1	-0.052683
ATP5E	0.052505
CAV1	0.051883
RASGRP1	0.051184
PLOD2	0.050925
NDUFAB1	-0.050506
RPL3	0.049511
DDX21	0.049437
RPL34	-0.049427
DHCR24	-0.049251
DDX60	-0.049230
RPL35	-0.049216
UBC	-0.049159
NPIPA1	0.048979
EEF1B2	0.047967
PLOD3	0.047874
MTCH1	-0.047828
TAP1	-0.047739
ITGAV	0.047576
TUBA1A	0.046813
GAPDH	-0.046657
PSAP	0.046624
AGR2	-0.046567
EEF1G	0.046404
BCAS3	0.045749
DDR1	-0.045034
MIR21	-0.044967
RPS9	0.044814
PTPRO	0.044605
ANP32B	0.044556
PUS7	0.044426
UQCRQ	-0.044110
MYL12B	-0.044043
NMI	-0.043846
RPL11	0.043795
PRDX1	-0.043508
NQO1	-0.043354
GNB2	-0.042981
IFIT3	-0.042967
MMADHC	-0.042926
NCOA3	-0.042804
LAPTM4B	0.042251
NRCAM	0.042203
KTN1	0.042154
PARP12	-0.042142
RPSA	0.041252
SLC38A2	0.040900
RPL22	0.040190
DHX15	-0.039744
MGAT4B	-0.039589
RNF149	-0.039508
MCM7	0.039491
LXN	-0.039370
MREG	0.039342
ENC1	-0.039236
RPS8	0.039190
SNHG6	-0.038946
TNFRSF21	0.038935
RPL6	0.038675
OAS3	-0.038637
RPLP1	-0.038596
UBB	0.038553
STAT1	-0.038445
APP	0.038350
ZRANB2	-0.038290
STAT2	-0.038260
CSDE1	0.038224
NPDC1	-0.037997
TMSB10	-0.037747
PPP1R15B	0.037492
HLA-F	-0.037341
TMEM243	0.037321
IFI27	-0.037194
KRT18	0.037112
LY6E	-0.036121
C1orf43	0.036076
LGALS1	0.035734
ACYP1	-0.035501
RPL9	0.035281
BST2	-0.035210
RPS20	0.035055
ALDH18A1	0.034857
TPT1	-0.034836
CFL1	0.034692
LSR	-0.034433
SLPI	-0.034337
HSP90AA1	0.034277
C6orf211	0.034120
TCEAL4	0.033941
IER5	-0.033888
PLSCR1	-0.033842
CHCHD1	-0.033835
TMBIM6	-0.033805
BRIP1	-0.033805
EIF4A1	0.033790
PTRH2	0.033743
FUCA2	-0.033165
YWHAG	0.033160
SLC7A5	0.033123
TRIM22	-0.033058
ZNF217	-0.032980
MORF4L1	-0.032789
UHRF2	0.032672
PTDSS1	0.032505
IFI35	-0.032403
RPL41	-0.032361
XAF1	-0.032271
RPS16	-0.032096
EFNA1	-0.032063
NCL	0.031800
HERC5	-0.031667
MMGT1	0.031626
POLR2J2	-0.031440
SLC35F5	0.031398
MARCKSL1	0.031368
LPCAT1	0.031116
TMEM97	0.031017
PTPLAD1	0.030947
NDUFA4	0.030877
NAA50	0.030796
SPCS1	-0.030774
CYP4Z1	-0.030686
RPS2	0.030611
GANAB	-0.030396
NBPF10	0.030288
CD164	-0.030277
RPL30	0.030186
MKNK2	-0.030186
CCT2	0.030098
MT1HL1	-0.029924
CERS2	-0.029915
PILRB	-0.029884
GAR1	0.029785
IRF7	-0.029647
TMEM205	-0.029628
POLE3	0.029592
MYC	0.029473
LRRC37A2	0.029464
PHB2	0.029375
KLF10	0.029351
MGST1	-0.029293
YBX1	0.029217
ANXA2P2	0.029205
FBL	0.029177
SREBF1	-0.029151
GPX4	-0.028963
CDIPT	0.028933
TM4SF1	-0.028784
VPS28	-0.028496
SLC9A3R1	0.028443
ALG8	0.028409
SHISA5	-0.028222
SRRM1	-0.028120
IFNGR1	-0.028032
HSPH1	0.027881
ATP5J2	-0.027831
EEF1D	0.027804
PNPT1	-0.027792
TNFRSF11B	-0.027599
DDX60L	-0.027544
SH3BGRL	0.027398
YIF1A	-0.027284
CLDN4	-0.027281
MRPL3	0.027217
FN1	0.027197
ATP1B3	0.027128
PFKFB3	0.027087
METTL9	0.027008
TFRC	0.026962
DDOST	0.026724
SAMD9L	-0.026706
MFSD1	-0.026575
YWHAE	0.026481
RPS13	0.026480
MRPL49	0.026466
RPL32	-0.026433
RPLP0	-0.026422
CDC37	-0.026403
HIF1A	0.026388
LBR	-0.026211
SGPP1	0.026159
ODC1	0.026113
EEF1A2	0.026053
HERPUD1	-0.025938
IRF9	-0.025919
SETD1B	-0.025609
COL5A1	0.025542
MDK	-0.025496
CDK5RAP3	-0.025449
GATA3	0.025402
PTGES3	0.025311
BAMBI	-0.025297
KARS	0.025136
TALDO1	-0.025116
TMEM60	-0.025105
RARS	-0.025084
POLD4	-0.025053
NDUFB9	0.025039
YWHAQ	0.025010
DDX47	0.025007
RSAD2	-0.024975
RPN1	-0.024964
NEAT1	-0.024838
GUSB	0.024816
RPL23A	0.024803
SLC26A11	0.024735
LAMA5	-0.024654
RAB13	0.024410
RPS23	0.024395
CDH1	-0.024376
PABPC1L	0.024341
PCMT1	0.024321
SSR4	0.024244
SFN	-0.024239
SELENBP1	-0.024198
SDC4	-0.024185
TNFRSF12A	-0.024179
CST3	-0.024173
LAMP1	-0.024166
MAPK6	-0.024151
ELOVL5	0.024129
CS	-0.024087
RPL36	-0.024084
HSPB8	0.024078
TUBA1B	-0.024030
TMEM140	-0.023936
MAL2	-0.023909
CD63	0.023886
AMZ2	0.023781
SAT1	-0.023722
UQCRH	-0.023677
LAP3	-0.023665
SGK3	0.023627
RPL28	-0.023601
HMGN3	0.023592
OASL	-0.023589
ID3	-0.023583
RTN4	0.023475
POR	-0.023436
RPL19	0.023358
FTH1	-0.023297
PKD1P1	0.023265
CCND1	0.023229
MEST	0.023211
HNRNPK	0.023210
SEC11A	0.023160
PRSS23	0.022967
UBE4A	-0.022896
TMX2	0.022886
BZW2	0.022873
EEF2	0.022817
TAPBP	-0.022724
H3F3B	-0.022704
HSPD1	0.022704
PPT1	0.022672
ANXA10	-0.022653
UBE2L6	-0.022630
FAM198B	0.022630
ETFA	-0.022606
DMTF1	-0.022580
NME1	0.022438
UGDH	0.022427
NFKBIZ	0.022422
BCAP31	-0.022379
PRKCSH	0.022371
PHF11	-0.022363
DYNLL1	0.022199
RPL7L1	0.022019
TMEM147	-0.022016
KIF5B	0.021988
SDHAP2	-0.021908
LOC91548	0.021904
CLDN7	-0.021857
ZNF721	-0.021849
TSPAN6	0.021848
ZMPSTE24	0.021841
RPS19	-0.021798
ZNFX1	-0.021766
LYPD3	-0.021737
SND1	0.021555
MRPL36	0.021538
EIF2AK2	-0.021530
UBE2E3	-0.021506
CLN3	-0.021473
SLC25A6	-0.021463
ATP6AP2	0.021455
PHF6	0.021396
EIF4B	0.021350
SSR2	0.021314
ISCU	0.021302
NAP1L1	0.021258
RPL27	0.021257
TSPYL2	-0.021242
MALL	-0.021222
METRNL	-0.021210
BTAF1	-0.021057
BRMS1	-0.020980
RAB10	0.020973
MRFAP1	0.020914
MSMO1	0.020906
DAD1	-0.020897
TPBG	0.020890
TUFT1	-0.020873
HIST1H2BD	-0.020862
DEGS1	-0.020851
PPIB	-0.020823
AHCY	0.020798
GTF2IRD1	-0.020725
CNBP	0.020709
SCML1	-0.020684
PSME1	-0.020670
COX7A2L	0.020654
CEBPB	-0.020651
UBAP2	0.020635
SPPL2A	-0.020616
EBPL	0.020611
LAMP3	-0.020592
PKD2	0.020582
AMIGO2	0.020521
GNB2L1	0.020505
DECR2	-0.020481
CPOX	0.020479
SLC35A1	0.020439
NRIP1	0.020420
ATP6AP1	0.020387
FAM122B	0.020300
TIMMDC1	0.020285
AKAP1	0.020147
SSR1	0.020061
ARL6IP1	-0.019995
SUCO	-0.019979
WDR54	0.019945
TXNDC12	0.019917
LAMTOR4	-0.019873
C19orf66	-0.019825
KPNA2	0.019777
RPL14	0.019737
PPIC	0.019716
NVL	-0.019704
RPS27	-0.019672
TRIM56	-0.019671
SP110	-0.019647
PANK3	-0.019590
TYRP1	0.019502
SS18L1	-0.019463
EPS8	-0.019463
NDUFA13	-0.019463
STARD7	0.019462
STX16	-0.019430
TPD52L1	0.019422
SPC24	-0.019393
DHX40	0.019376
RPS11	-0.019376
LINC01003	-0.019363
CDKN1B	0.019363
DDB2	-0.019312
CREG1	0.019286
EIF2A	0.019241
NSA2	0.019116
NAT10	0.018891
LAMTOR1	-0.018861
RXRA	0.018825
TAP2	-0.018795
INPP4B	0.018791
GLA	0.018759
NCOA4	0.018730
CHKA	-0.018721
SLC25A5	-0.018707
TBCA	-0.018694
PARK7	0.018615
YWHAZ	0.018606
PSME2	-0.018597
LOC642361	-0.018536
KDELR1	0.018508
MYL6	-0.018454
RPL31	-0.018419
PAM	0.018418
ABAT	0.018402
LINC01004	-0.018382
INSIG2	-0.018270
HIST1H2AC	-0.018222
SRP9	-0.018217
XRCC5	0.018172
HIST1H2BK	0.018157
SEMA4C	-0.018150
LINC00493	-0.018105
SPTLC1	-0.018089
CRABP2	-0.018052
RRM2	0.018013
LTA4H	0.017963
MARVELD2	0.017938
BAZ1A	0.017928
ASAP2	0.017928
NOTCH2NL	0.017928
MZT2A	-0.017926
AIM1	0.017872
IP6K2	-0.017864
PABPC4	0.017861
SRPRB	0.017834
STARD4	-0.017798
HNRNPA3	-0.017773
ILF2	0.017763
LGALS3	-0.017763
NPC2	-0.017714
ARF4	0.017689
TRAM1	-0.017677
MTHFD1	0.017658
SMNDC1	0.017650
DSP	-0.017637
RPS15	-0.017619
ZNRF3	0.017599
FLJ31306	-0.017556
RPL7	0.017529
DNTTIP2	0.017509
PFDN4	-0.017500
ERO1L	0.017452
BTBD6	-0.017435
PSMA4	-0.017399
AARS	0.017376
IER3	-0.017374
ATRAID	0.017357
RNASEK	-0.017308
SF3B1	-0.017288
DDX58	-0.017279
SPNS1	-0.017275
CBX1	0.017259
IK	0.017210
EMP2	-0.017198
TMEM258	0.017189
AQP3	-0.017128
TUG1	0.017122
S100A11	0.017115
DLD	0.017098
SCD	-0.016980
DKC1	0.016961
ALDOA	-0.016955
PARP14	-0.016952
YWHAB	-0.016951
CARKD	-0.016932
BFAR	0.016919
MAGEH1	-0.016896
PPP1R35	-0.016887
BLVRB	-0.016871
RPL37A	0.016827
CPSF4	0.016823
NOB1	0.016811
ATP13A3	0.016806
NETO2	0.016751
FREM2	0.016746
ASPH	-0.016734
PDZD11	0.016732
RPL12	-0.016725
PNMA1	0.016687
LDOC1	0.016656