!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!ligand_name	Interleukin-6 (IL-6)
!ligand_id	Drug Bank ID: BE0000918
!cell_type	liver
!organism	mouse
!end_metadata
SAA1	0.240516
CXCL2	0.181730
STEAP4	0.180337
GADD45A	0.148779
SOCS3	0.135465
GADD45G	0.135247
LCN2	0.096910
PHLDA1	0.094500
SERPINA10	0.090532
PIM1	0.084467
ZFP36	0.080022
OSGIN1	0.079470
SAA2-SAA4	0.079393
JUN	0.076055
KCNK5	-0.072826
EGR1	0.072781
PLK3	0.070839
WSB1	0.070388
CIART	-0.070372
NFIL3	0.069907
CYP1A1	-0.067835
FGA	0.067822
CISH	0.066530
BTG2	0.065704
BCL3	0.065350
ARRDC3	-0.062409
SOCS2	0.060201
ID3	0.059057
JUNB	0.059045
G0S2	-0.057482
BHLHE40	0.057457
SLC41A2	0.056987
ZFP36L1	0.056894
LEAP2	0.055565
TIFA	0.054907
B4GALT1	0.053768
EFNA1	0.053117
RND3	0.051712
IRS2	0.050687
MAP2K6	-0.048804
ARID5B	0.048353
MYC	0.047005
ACMSD	-0.046298
SLC39A14	0.046144
PDK4	0.046024
IL17RA	0.045999
GATA6	0.045623
SULT1E1	-0.045188
HMOX1	0.044975
PPP1R3C	-0.044809
EID3	0.044558
E2F8	0.043573
ARHGEF26	0.042821
ARID5A	0.042412
ID2	0.041702
SLC41A1	0.041597
FBF1	0.041589
LRG1	0.041535
TSC22D3	-0.041036
MAP3K8	0.039972
MFSD2A	-0.038734
PIM3	0.038453
TFF3	-0.038407
SLC37A1	0.038037
ASNS	-0.037902
SERPINA7	0.037587
SPATA2L	-0.037365
HIST1H3G	-0.036855
SLC17A2	0.036568
MYD88	0.036455
S100A8	0.036424
C12orf45	0.036082
IL1R1	0.035671
FGF21	-0.035512
DDIT4	-0.034930
ONECUT1	0.034478
WDR45B	0.034365
YPEL2	0.034273
MAFB	-0.033822
TLE3	0.033754
TSKU	-0.033629
SLC38A2	0.033126
TNIP2	0.032567
GAS6	0.032429
SPP1	0.032073
ATF3	0.031739
BACH1	0.031617
HES1	0.031473
NFKBIZ	0.031342
ITIH4	0.031283
PTP4A1	0.031096
PFKFB3	0.031096
TIRAP	0.031080
APCS	0.030927
KLF6	0.030915
STAT3	0.030532
ETNPPL	-0.030494
FAS	0.030354
TGM1	0.030281
LITAF	0.029999
XBP1	0.029873
SNAI2	-0.029778
PLCXD2	0.029601
AQP8	0.029539
FAM110C	0.029515
PLK2	-0.029161
FOXQ1	0.029095
UPP2	-0.028879
TOB1	-0.028532
CA3	0.028476
IKZF5	0.028034
LPAR6	0.027991
ACOT2	0.027989
RAB20	0.027678
RIPK1	0.027597
PNP	0.027547
IRF9	0.027409
MYH9	0.027395
LEPR	-0.027361
STAP2	0.027276
FOXS1	0.026895
SLC15A2	-0.026816
SLC43A1	0.026806
UGCG	0.026717
PCM1	0.026602
GPR146	0.026596
CXCL13	0.026364
CCNF	-0.026350
SERPINA9	-0.026252
MMP7	0.025965
IGFBP1	0.025748
GTF3C2	-0.025698
ZC3H12A	0.025659
GCNT2	0.025572
APBA1	-0.025398
IQCG	-0.025316
PDZRN3	0.025269
IER3	0.025229
SOX9	0.025224
SERPINA12	0.025132
CYP17A1	-0.024982
MUSTN1	0.024964
CYP1A2	-0.024953
C7orf50	0.024919
RASGEF1B	-0.024768
NRP2	0.024760
P2RY4	-0.024559
FGG	0.024543
GAN	0.024468
KLHDC7A	0.024408
BCL6	0.024404
OR5D16	-0.024372
ZFAND4	-0.024366
ZSCAN12	-0.024282
SLA	0.024246
SH3BP2	0.024233
ISG20	0.024101
SLC30A10	0.023848
IER5	0.023842
SLC9A3R1	0.023774
S100A6	0.023747
B3GALT1	0.023617
INF2	0.023528
DDX19B	0.023394
ALDH1B1	-0.023291
IGFBP6	0.023260
LGALS1	0.023258
PAQR9	0.023256
INSIG1	-0.023220
STAT2	0.023184
SLC35G1	-0.023103
CYB561	0.023077
CPEB4	0.023031
ATG14	0.023021
IL22RA1	-0.022850
PRKAB1	0.022831
ESRRG	0.022780
GOT1	-0.022701
DUSP1	-0.022696
SNX10	0.022689
ICAM1	0.022643
PTPN2	0.022643
AHR	0.022639
ZNF286A	-0.022571
NTSR1	-0.022551
TIPIN	-0.022511
PER1	-0.022471
LXN	0.022385
OR5AK2	0.022376
MID1	0.022353
DONSON	0.022229
ASIC5	-0.022128
SLC45A3	0.022117
RRAGD	0.021978
CSRNP1	0.021816
CLDN14	0.021810
SLC30A5	0.021799
UNC13B	0.021697
TEDDM1	0.021539
SERTAD3	-0.021539
SLC17A8	0.021494
TPD52L3	-0.021483
UBE2U	-0.021472
SMAD7	-0.021357
CEBPB	0.021352
MAFA	-0.021336
GPR21	0.021296
THEMIS	0.021263
CAMK2B	-0.021185
RNF31	0.021178
CLCN7	0.020978
OAS1	-0.020908
CASC1	0.020828
SERPINB1	0.020790
SULT1C2	0.020776
COX7A1	0.020665
NXPE2	0.020595
C6orf141	-0.020503
TACC2	0.020478
C14orf80	-0.020461
HSPB1	0.020455
SLC15A4	-0.020453
FGL1	0.020356
EPB41L4A	0.020333
CCL3L3	0.020245
SYT2	-0.020210
HSPB8	0.020206
RBM12B	-0.020184
IFNK	0.020143
PEX26	0.020140
SHQ1	0.020119
SLC25A30	0.020102
WEE2	0.020102
DHTKD1	-0.020092
TOB2	-0.020032
OR5B3	-0.020019
LRIG1	0.019978
CD19	-0.019966
STAT1	0.019906
TEX36	-0.019905
RIBC1	0.019903
SLC44A5	-0.019870
FRMPD1	-0.019848
C10orf10	0.019805
C5orf47	-0.019753
PLSCR1	0.019752
OR10AD1	0.019696
CTSC	0.019674
SAT2	-0.019648
ABCG8	-0.019624
HSD17B6	-0.019612
SERPINB8	0.019601
SESN2	-0.019594
CD36	0.019557
GATA3	-0.019512
CTH	-0.019484
DOK2	0.019474
ZNF627	0.019436
KLF13	0.019371
SLC25A25	0.019270
SCARA5	0.019150
HTATIP2	-0.019138
USP2	-0.019126
SH3YL1	0.019109
LRRC8A	0.019103
OR8K3	-0.019051
TMEM86B	-0.019044
DDX18	0.019036
OR5C1	-0.019006
CCP110	0.019004
C20orf173	-0.018993
OTOS	-0.018991
TEKT5	0.018955
OR5I1	0.018935
INMT	0.018886
HSP90AA1	0.018875
G6PC	-0.018868
NTF3	0.018858
ZNF217	0.018843
ZBTB25	-0.018839
ZRANB3	0.018776
ZNF559-ZNF177	-0.018761
ABCG5	-0.018760
NRP1	0.018747
TAF5	0.018742
UBE2L6	0.018733
TNFRSF1A	0.018725
CHAC1	0.018700
ETNK2	-0.018693
DPT	0.018624
CREB3L2	0.018604
IL13RA1	0.018589
RSAD2	0.018573
OR56A3	0.018510
TPPP	0.018509
SEC22C	-0.018503
CITED2	-0.018477
SULT6B1	-0.018476
EDC3	-0.018474
FAM129A	0.018470
RPP38	0.018448
CLP1	0.018402
BAG3	0.018365
SPA17	0.018354
BTBD16	-0.018347
SHROOM1	0.018343
SERPINA3	0.018305
MCC	0.018168
C8orf37	-0.018147
RSPH1	-0.018069
FABP5	0.018065
TMEM25	-0.018040
OR6C65	0.017975
IP6K2	0.017921
SLC45A2	-0.017920
VN1R4	-0.017884
CASP8	0.017874
IRF2BP2	0.017782
FAM204A	0.017773
RTP4	0.017773
CMPK2	0.017768
NFYB	0.017762
CRY2	-0.017758
LPIN2	-0.017753
RNF19B	0.017704
C17orf80	0.017700
FAP	-0.017690
C2CD4A	-0.017626
HLA-DQA1	0.017611
KIAA0232	-0.017542
SLC46A3	-0.017532
SLC13A5	0.017520
CPLX3	-0.017516
GPT	-0.017514
C15orf60	-0.017469
CRP	0.017351
BCDIN3D	-0.017267
RMDN1	-0.017248
GATM	0.017221
KANSL1L	-0.017211
FGB	0.017211
GPR1	0.017133
KERA	-0.017132
CTSK	-0.017098
LYPD4	0.017090
PPARG	0.017069
ATCAY	-0.017063
CA13	0.017043
GPR150	-0.017040
SCN4A	0.017033
FLOT1	0.017012
GIPC3	0.017010
TIMD4	0.017009
EZH2	0.017003
FMO4	-0.016994
FREM3	0.016960
OR1A1	-0.016953
COL6A5	0.016924
TRIM29	-0.016849
ERLEC1	-0.016839
BCL9	-0.016831
PCDH11X	-0.016813
COMT	0.016785
C10orf62	-0.016680
ANXA9	0.016595
SLC7A2	-0.016591
RGS7BP	-0.016585
EIF2AK2	0.016582
OR6B1	-0.016522
ZNF182	0.016464
SEMA4B	0.016460
POLI	0.016441
CACNA2D4	0.016408
NAIP	0.016399
LPGAT1	0.016383
CLDN2	0.016349
CYP2C18	0.016336
HAL	-0.016324
ELOVL6	0.016317
GUCY1B3	0.016308
F11	-0.016293
RNF39	-0.016286
ZNF518B	0.016278
CLK1	-0.016273
CPNE8	0.016258
GLS2	-0.016252
SCD	0.016236
SERPINE1	0.016228
IL6ST	0.016227
ERC2	0.016222
CD207	0.016220
OR6A2	0.016209
ERLIN1	0.016207
PPARGC1A	-0.016193
TRIM21	0.016179
C4orf26	-0.016178
TSLP	-0.016140
SCN5A	-0.016136
RASL11B	-0.016126
STARD13	0.016120
ELOVL3	0.016115
IL15RA	0.016110
CCDC138	0.016105
CDC42EP3	0.016061
LUC7L3	-0.016055
C1orf192	-0.016031
MYCN	-0.016028
AKAP4	0.016027
RNF38	0.016013
MAML1	0.015999
ZBED5	-0.015993
MAP3K1	0.015990
METTL20	-0.015977
SLC17A6	-0.015975
FAM131B	-0.015974
RERGL	0.015973
ARL4D	-0.015957
DDX60	0.015933
KIFC3	0.015856
LPIN1	-0.015845
FGL2	0.015825
HHEX	-0.015825
CDKN2A	0.015819
GPRIN1	-0.015790
CYS1	0.015782
HIST1H2BN	0.015725
SHB	0.015669
GOLPH3L	0.015667
LOC100505478	0.015640
PEG3	0.015613
PFDN1	-0.015611
SLC6A12	-0.015604
OR4D2	-0.015579
CDIP1	-0.015579
EXTL3	0.015574
EFEMP1	0.015571
SLC11A2	0.015568
FAM209B	-0.015568
SEC61G	0.015567
TRIB3	-0.015563
GPRC6A	0.015556
SEBOX	0.015547
ACSL4	-0.015521
PQLC2	-0.015507
KHDC1L	-0.015501
IL9	-0.015474
ANKLE1	0.015440
CCNB2	0.015432
NOP58	0.015421
IBSP	0.015409
CEMIP	0.015401
POLG2	-0.015397
ZMYM5	-0.015389
FITM1	0.015350
FAM131C	0.015344
COMMD7	0.015335
FABP9	0.015335
FKBP14	-0.015297
DQX1	-0.015276
GPRC5B	0.015268
OR5L2	-0.015250
CDKN2D	0.015243
CCL25	0.015230
TFEC	0.015230
SPON2	0.015213
GLT1D1	-0.015154
GNA14	0.015131
NANOS3	-0.015115
SELV	-0.015092
DGKI	0.015086
WNT9A	-0.015084
PANK1	-0.015076
ABCC4	0.015068
NEUROD4	-0.015067
SEMA5B	0.015061
VNN1	0.015058
ID1	-0.015047
OR13F1	-0.015043
PLEKHF1	-0.015035
DOK3	-0.015035
PHC1	-0.015011
HIST1H2BI	0.015003
DYRK3	0.014988
ACOT1	0.014982
GTDC1	-0.014972
ZNF746	-0.014970
ZCCHC5	0.014962
SLC6A19	-0.014948
ZC3H8	-0.014944
GLUL	0.014943
NRAS	0.014925
DIRAS1	-0.014912
RIOK1	-0.014910
ITIH3	0.014907
C4orf45	-0.014891
TTC9	-0.014889
SLC25A32	-0.014881
NKD2	0.014875
AQP11	-0.014866
KCTD9	-0.014861