!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!cell	A375 16R6 (A375 derived GSK2118436 resistance clone)
!perturbation	GSK2118436
!disease	Melanoma - 24hrs - 30uM
!end_metadata
MT2A	-0.229644
HIST1H4C	-0.196957
FTH1P5	0.145260
FTL	0.132613
MT1H	-0.131846
FTH1	0.127643
MT1X	-0.111711
ND2	-0.109815
ID3	0.107421
FABP5	-0.094701
UBE2S	-0.094103
CAV1	0.092176
RPL30	0.090308
NGFRAP1	0.089611
BASP1	0.084141
NNMT	0.084037
TMSB10	0.082576
RRM2	-0.082335
CCND1	-0.079705
RPS13	0.079670
PDLIM1	0.079668
FBL	-0.079529
FOSL1	-0.079393
PGAM1	0.077948
PTX3	-0.076635
KRTAP2-3	-0.075782
ID1	0.073648
AP3S1	0.073522
PHB2	-0.070575
CTGF	-0.070118
PTDSS1	-0.069073
HSPB1	0.068552
TPT1	0.066236
HSPA1A	-0.065822
NOP10	-0.065810
MMP3	0.065799
ANP32B	-0.064556
ZWINT	-0.063972
CCT3	-0.062859
KRT18	-0.062118
TUBA1A	0.062086
COTL1	-0.061734
PTMA	-0.061076
NOP58	-0.060166
GABARAP	0.059737
EMG1	-0.059195
TOP1	-0.059192
MT1HL1	-0.058821
CTPS1	-0.057547
EPHA2	-0.057216
HSP90AA1	-0.056301
SNAPC1	-0.056275
B2M	0.056178
PLAC8	0.055973
DKK1	0.055513
RAN	-0.054979
DKC1	-0.054595
DDX39A	-0.053219
UAP1	-0.053172
TIMP1	-0.052424
UGCG	0.052263
PALLD	0.052198
LGALS1	0.052189
EIF4A1	-0.052083
HSPH1	-0.051827
RPL9	0.051636
HNRNPAB	-0.051425
TXNRD1	0.051306
YWHAQ	0.051000
MYL6	0.050619
TGFBI	0.050543
TUBB4B	-0.050492
SET	-0.050469
SRM	-0.050108
S100A10	0.049912
EBNA1BP2	-0.049734
DUSP5	-0.049404
SNHG6	0.049399
PABPC3	0.047952
MRPL33	0.047586
PFN1	-0.046568
DIO2	0.046532
NOP56	-0.045955
MALAT1	0.045533
EIF3D	-0.045114
ATP6	-0.044810
RPL26	-0.044743
SSR3	-0.044734
SNRPB	-0.044218
CCNG1	0.044119
RPS20	0.043641
NME1	-0.043389
ANKRD1	-0.043382
SPANXB1	0.043355
CDC20	-0.043281
PFDN2	-0.042966
ADRM1	-0.042797
TMEM14B	0.042748
NCL	-0.042438
H3F3B	-0.042231
PPM1G	-0.042108
CKS1B	-0.042003
KPNB1	-0.041856
PRSS23	0.041742
HIF1A	0.041615
GSTO1	-0.041259
TMEM14C	0.041102
PSMB3	-0.040724
SLC43A3	-0.040708
CIRH1A	-0.040566
EIF1	-0.040457
SRP14	0.040318
ARL6IP1	0.039351
OSBPL9	0.039213
MYL12B	0.039034
HSP90AB1	-0.038753
LAPTM4A	0.038363
FTSJ3	-0.038265
COX1	0.038253
KRT80	0.038221
DDX1	-0.037992
HMGN2	0.037924
DUSP6	-0.037755
KARS	-0.037670
C12orf75	0.037521
TOMM5	-0.037398
RPS15	-0.037300
AP2S1	-0.036934
RPL34	0.036657
TRIM58	0.036592
C20orf24	-0.036575
SCG5	0.036414
SLC38A2	0.035994
GPX4	0.035977
RPS25	0.035902
SRP9	0.035755
GNG10	0.035663
GBE1	0.035596
OAT	0.035423
TFRC	-0.035333
COMMD8	0.035262
LINC01419	0.035242
AMIGO2	-0.035164
ATF4	-0.035124
LIMA1	0.035079
NAP1L1	0.035002
SNRPD3	-0.034979
HMGB2	0.034972
NEAT1	0.034946
MAGEA4	0.034910
CCDC59	-0.034786
TUBA1C	-0.034670
EIF3G	-0.034659
SLC20A1	-0.034360
SKP1	0.034240
UBA52	-0.034110
YWHAB	-0.034087
CAPN2	-0.034044
CYR61	-0.033990
SLC7A5	0.033927
TMX2	-0.033857
EIF4EBP1	-0.033743
TUBB2A	0.033716
RPL8	0.033700
PDCD10	0.033407
PA2G4	-0.033339
FEN1	-0.033313
PTBP1	-0.033299
LYAR	-0.033288
S100A16	-0.033151
HSPA8	-0.033074
COX2	0.032978
RPS3A	0.032927
SRSF9	-0.032734
EIF3K	-0.032691
PLS3	0.032529
FEZ2	-0.032392
RBPJ	-0.032328
MAT2A	-0.032314
ANXA1	0.032242
POLR2H	-0.032114
LINC00973	-0.032064
DYNLL1	0.032026
RPL36	0.031677
RPS29	0.031547
GAPDH	0.031357
RHOBTB3	0.031274
MSN	-0.031260
LDHA	0.031228
MTHFD2	-0.031128
HMGA1	-0.031021
NHP2	-0.030974
RAI14	-0.030904
PLAUR	-0.030893
RPN2	-0.030878
SNHG19	0.030803
ADM	-0.030773
M6PR	-0.030682
IGFBP3	0.030650
ELOF1	-0.030648
IL13RA2	-0.030585
RPL27	-0.030555
YWHAZ	0.030531
FAM96A	0.030505
DDX21	-0.030449
MGST1	0.030422
TUBG1	-0.030247
TMA7	-0.030244
UQCRH	-0.030156
TMEM158	-0.030015
RUVBL1	-0.029909
HEG1	0.029813
GGCT	-0.029763
SNHG17	-0.029721
CEBPB	0.029695
IER2	-0.029672
GRPEL1	-0.029610
EIF6	-0.029475
RPS27L	0.029369
DPM1	0.029233
SNHG1	-0.029156
PNPT1	-0.029093
CLIC1	-0.029057
NUDC	-0.029047
IRAK1	-0.028998
GNL3	-0.028896
COX6C	0.028860
ATIC	-0.028661
BZW2	-0.028647
UCA1	-0.028570
RPL32	0.028568
RTN4	0.028547
ARL6IP5	0.028547
UBC	-0.028517
MORF4L1	0.028334
FST	-0.028333
MCM7	-0.028160
BNIP3	0.028134
ATP6V0B	-0.028057
RHOA	0.028005
CDIPT	-0.027929
KISS1	-0.027895
CDK4	-0.027795
COPRS	-0.027591
FOXD1	-0.027579
PRPF19	-0.027405
NPM1	-0.027336
SERBP1	-0.027316
CFAP20	-0.027260
SF3A3	-0.027164
FXYD5	-0.027134
ARPC2	-0.027119
WFDC21P	0.027115
RCN1	0.026993
SFN	0.026980
NDUFA4	0.026884
MTCH1	-0.026849
CD274	-0.026818
CDC37	-0.026670
RPL4	0.026591
ADI1	0.026495
SNRPA	-0.026488
ESM1	-0.026445
TUFT1	0.026401
DCTPP1	-0.026351
ODC1	-0.026279
PHB	-0.026270
RPF2	-0.026225
SPARC	0.026190
EXOSC4	-0.026097
EIF5	-0.026083
ERBB2IP	0.026077
NOC3L	-0.026070
TMEM14A	0.026017
NOL11	-0.025994
CSRP2	0.025982
CDKN2C	0.025940
GARS	-0.025895
TUBB6	-0.025798
HMGN1	0.025738
RPS12	0.025730
NACA	0.025705
SOD1	0.025685
GLRX	-0.025666
ETF1	-0.025660
PHLDA2	-0.025612
GTF3A	-0.025585
PNP	-0.025583
CD59	-0.025526
IER3	-0.025501
CEBPZ	-0.025472
ATOX1	-0.025462
RNPS1	-0.025399
NDUFB5	0.025340
CPA4	0.025274
EIF4A3	-0.025260
DDX47	0.025217
SNRPG	-0.025208
NOLC1	-0.024987
ACTN1	-0.024930
GHITM	0.024915
WAC-AS1	-0.024901
TUBB	-0.024879
CDKN1B	0.024769
GAR1	-0.024594
UQCRB	0.024508
ERRFI1	-0.024490
PUF60	-0.024463
CDC123	-0.024449
CTNNAL1	-0.024413
AATF	-0.024342
TMEM123	0.024340
ATP5H	0.024318
COX7A2	0.024283
SNHG16	-0.024173
CS	-0.024136
RPS7	0.024093
RPL35	-0.023941
ATP5J	0.023866
RPL17	0.023843
CCDC86	-0.023805
RPL27A	0.023729
BTF3	0.023723
MRTO4	-0.023565
SNRPD1	-0.023533
UNG	-0.023514
STARD7	-0.023510
TIMM10	-0.023448
IFI30	0.023216
SF3B5	-0.023109
SLC25A19	-0.023016
AHSA1	-0.022998
CCT7	-0.022971
CTDNEP1	-0.022848
JTB	-0.022773
RPL23A	0.022752
HDGF	-0.022651
DTL	-0.022626
RNF11	0.022616
SMAGP	-0.022456
PRPF4	-0.022263
HADHB	0.022256
RPL37A	0.022174
DHX15	-0.022165
SH2B3	-0.022155
COX7B	0.022064
DAZAP1	-0.022029
FARSA	-0.022016
CALM2	-0.021982
MRPS34	-0.021965
UHRF1	-0.021918
GTF3C6	-0.021889
POLE3	-0.021869
RPIA	-0.021859
CD24	0.021847
DSTN	0.021682
CREG1	0.021606
FSTL1	0.021496
CISD1	-0.021475
CSRP1	-0.021397
HOXC6	0.021354
RPL10A	0.021322
ANXA2P2	0.021251
SERPINE2	-0.021246
EEF1A1	0.021177
CTSC	-0.021167
NDUFB4	0.021133
CCT6A	-0.021097
RPS18	0.021052
UTP3	-0.021004
EVI2A	0.020999
PRDX1	0.020978
TNFRSF12A	-0.020958
RPL7A	0.020938
MT1F	-0.020931
NHP2L1	-0.020849
TSPAN13	0.020820
ATP5G1	-0.020763
PSMC4	-0.020760
POP7	-0.020748
SSRP1	-0.020694
MIR21	0.020550
RRS1	-0.020543
MRPL21	-0.020528
ITM2B	0.020513
MT1G	-0.020499
PTP4A2	-0.020488
RPS5	-0.020341
DNTTIP2	-0.020303
DCBLD2	-0.020292
HIGD1A	0.020262
SLC25A3	0.020259
MRPL9	-0.020210
RPL41	0.020158
RAD23A	-0.020155
HPCAL1	-0.020147
EIF3I	-0.020146
DDIT4	0.020141
MRPS35	-0.020138
S100A6	0.020126
TFPI2	-0.020074
RPL38	0.020071
SLC25A5	-0.020065
CBWD1	0.020033
DEK	0.020018
TUBA1B	-0.019984
PSMA7	-0.019957
GNAI1	0.019938
SMURF2	-0.019891
MAFF	-0.019883
LSM10	-0.019881
NPC2	-0.019854
PSMC1	-0.019840
MRPS30	-0.019826
KTN1	0.019755
TNPO1	-0.019729
MLLT11	0.019719
CCT5	-0.019712
AGPAT9	-0.019689
CLTA	-0.019655
TOP2B	0.019645
BIRC2	-0.019631
BRI3BP	-0.019612
ARPC5L	-0.019610
OAZ1	-0.019578
RPS10	0.019569
ANLN	0.019556
MRPL36	-0.019552
PSMB5	-0.019545
MRPS21	-0.019532
PFAS	-0.019488
ENO1	-0.019412
DUSP4	-0.019323
JUND	0.019282
EXOSC9	-0.019280
EIF3B	-0.019235
RPL36A	0.019235
HMMR	0.019221
SCP2	0.019199
SUMO2	-0.019160
AJUBA	0.019146
TOMM22	-0.019113
PHLDA1	-0.019102
RPS23	0.019061
HMGA2	-0.019021
FAM216A	-0.018977
CLIC4	0.018898
USP1	-0.018894
RARS	-0.018879
MAGEA12	0.018874
HERPUD1	0.018874
EIF2B2	-0.018870
PSMD11	-0.018867
APOBEC3B	0.018847
CFL2	0.018846
HSD17B10	-0.018846
POLR2L	-0.018836
RPL7	0.018748
ANXA5	0.018714
MRPL27	-0.018691
HMGN3	0.018645
EPS8	0.018630
PHC2	-0.018620
WDR83OS	-0.018577
PGM1	0.018573
BCAP31	-0.018544
RAC1	-0.018538
TPM1	0.018537
PTGES3	-0.018501
ECI2	-0.018501
MRPS2	-0.018497
EEF1G	-0.018461
KIAA0020	-0.018365
RPS27A	0.018344
PRMT1	-0.018337
TIMP2	0.018297
ELK3	-0.018272
PTPRF	-0.018249
HIST1H2BK	-0.018239
UBE2M	-0.018181
BCCIP	-0.018170
PPA1	0.018168
ALDH1A3	0.018124
HARS	-0.018065
GPI	-0.018061
WBP5	0.018051
TPI1	-0.017995
AUP1	-0.017965
CSE1L	-0.017952
PDHB	0.017884
CDKN3	0.017837
TMEM138	-0.017803
RPS24	0.017759
RRAGA	0.017753
CSNK2B	-0.017695
MAGEA6	0.017685
RAE1	-0.017681
RPS11	0.017672
CDC26	-0.017641
ADSL	-0.017620