!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!organism	Homo sapiens
!old	72-79
!young	52-56
!cell_type	CD4+Tlyphocytes
!age_unit	year
!organism	human
!end_metadata
GNLY	0.064742
HLA-A	-0.062624
HLA-DRB5	0.061649
NKG7	0.060632
HLA-DRB1	0.060141
SPATA13	-0.058068
GNLY	0.057852
GZMH	0.051756
CCZ1B	-0.049769
S1PR5	0.048008
PTPRC	-0.046934
FGFBP2	0.045912
PTPRC	-0.043472
AAK1	-0.041989
CCL3L3	-0.041883
GPR56	0.041640
TSPAN18	-0.041464
HLA-DQB1	-0.041375
FBXW7	-0.040541
GPR56	0.040322
PRF1	0.039383
DEFA1B	0.038086
BIRC3	-0.037208
GZMB	0.037172
CREBBP	-0.036869
KRT72	0.036606
EOMES	0.036461
LMNA	-0.036127
MFF	0.036051
DEFA1	0.036041
MT1E	0.035828
BCLAF1	-0.034784
CCL3L1	-0.034485
DEFA1B	0.034294
OSBPL8	-0.033272
CX3CR1	0.033250
CCL3L1	-0.033116
MUC6	-0.032828
GZMA	0.032346
DEFA1B	0.032281
DEFB123	-0.032279
HOPX	0.032050
ARID4B	-0.031812
COA3	-0.031666
PRSS23	0.031602
KLRD1	0.031283
IL18RAP	0.031175
YBEY	-0.030956
RNF19A	-0.030790
PASK	-0.030373
DEFA3	0.029879
PASK	-0.029839
NBPF9	-0.029382
SLC7A5	-0.029278
RORA	-0.028970
CST7	0.028935
PTPRA	-0.028818
VASP	0.028678
IER3	-0.028646
ITM2A	-0.028575
KRT73	0.028571
CD8A	0.028472
ITGAM	0.028370
GRB2	-0.028343
ELF2	-0.028123
RAD21	-0.028080
MBNL3	-0.028030
CCL3L1	-0.027895
GNL3L	-0.027588
NBPF10	-0.027115
GREB1	-0.026811
GNLY	0.026645
DDX17	-0.026619
CHN1	0.026524
FAM13A	-0.026471
MIAT	0.026320
YBEY	-0.026294
NFAT5	-0.026289
IL16	-0.026275
LUC7L3	0.026117
UHMK1	-0.026115
MAFF	-0.025989
UBE2D2	-0.025898
LGALS12	-0.025885
VSX2	-0.025626
FMO2	-0.025580
CXorf38	-0.025501
GOLGA6B	0.025457
CCL5	0.025374
GPR114	0.025281
ADM	-0.024844
NAPSB	-0.024584
TARP	0.024395
NEU4	-0.024362
RGCC	-0.024351
EGR1	-0.024150
SAP30	0.024096
B3GAT1	-0.023952
CD1C	-0.023870
CRYZ	0.023827
FBXW8	-0.023634
SERPINB7	-0.023604
APOBEC3G	0.023509
KLRD1	0.023411
ADAM15	-0.023327
HLA-DRB6	-0.023279
B4GALT5	0.023200
PPAPDC1B	-0.023138
OMA1	0.022908
FCER1A	-0.022881
SPIN1	-0.022764
DCLK1	-0.022660
MCOLN2	0.022645
SH3KBP1	-0.022614
KIAA1143	-0.022598
FSTL4	-0.022497
ADHFE1	0.022480
UBE2H	-0.022435
FEV	-0.022401
ZRANB1	-0.022396
KCNT1	0.022394
SEMA6B	-0.022369
MAP3K7CL	0.022336
TAOK1	-0.022234
COL2A1	-0.022223
HIST1H2BJ	-0.022218
LAG3	0.022204
CD8A	0.022181
XAF1	0.022150
CD3G	-0.022094
PTPN12	0.022085
ARHGAP11A	-0.022051
RAB38	0.021968
HNRNPR	-0.021934
PLCH2	-0.021862
DPCR1	-0.021833
RBMS1	-0.021814
VWA7	-0.021795
NAPRT	0.021772
CCL3	-0.021757
ERGIC2	-0.021742
MATK	0.021654
SNORD13	0.021649
STRN	-0.021634
BSG	0.021633
AKR1C2	-0.021599
CFL2	-0.021587
VEGFA	-0.021535
UHRF2	0.021435
NR2F2	-0.021419
UNC13A	-0.021414
NUFIP2	-0.021372
RAB33A	-0.021363
TGFBRAP1	-0.021360
VPS13C	-0.021280
RWDD2A	-0.021279
PPFIBP2	0.021166
PRR5L	0.021158
SAMD3	0.021083
GFI1	0.021074
KIR2DL4	0.021039
SGK3	-0.021016
RHOC	0.021000
ZNF815P	-0.020939
GBP5	0.020903
USP36	-0.020891
ARL4A	-0.020851
RNF39	-0.020850
KLRF1	0.020843
MYH4	-0.020843
TTC38	0.020834
ARID4B	-0.020830
HIST1H2BB	0.020804
GSDMB	0.020800
SMAD7	-0.020791
GPR183	-0.020783
GLIPR1L2	-0.020734
SLC25A36	-0.020729
PSTPIP2	0.020673
SAMD3	0.020657
KLF10	-0.020620
SAMD3	0.020610
CSAD	0.020605
PTGDR	0.020598
NCBP1	0.020543
BTN3A2	0.020476
HOXB1	-0.020420
APOBEC3G	0.020375
HOXB6	-0.020346
POLR1D	-0.020334
HCN4	-0.020234
HES1	-0.020217
HKDC1	0.020159
UGDH	0.020159
IRX6	-0.020155
RAP2A	0.020140
DNAJA4	0.020078
ITGA4	0.020062
CRISP2	-0.020051
OGT	0.020036
SENP2	0.020024
GRASP	-0.019966
COL12A1	-0.019947
PDLIM7	-0.019946
CCL5	0.019937
PTPN22	0.019935
GDPD4	-0.019925
NFS1	0.019811
CXCL8	-0.019805
ING2	0.019789
GPRIN3	-0.019788
GPR119	-0.019772
LGALS9	0.019752
C18orf32	0.019752
MKKS	0.019741
CTAG2	0.019703
BCL2	0.019697
HIST1H4E	0.019692
TPD52L2	-0.019654
FAM43A	-0.019617
SNORD73A	0.019569
SUSD1	0.019527
PHF5A	-0.019510
COL18A1	0.019446
SEPT6	-0.019439
CXCL8	-0.019386
METTL3	0.019345
CELSR1	-0.019294
PRR15L	-0.019286
UBN2	-0.019251
NUPL1	-0.019249
YTHDC1	-0.019233
PLD2	-0.019225
PI15	-0.019189
ANKRD36B	-0.019177
PSTPIP1	0.019151
EVA1C	0.019140
HLA-DRB4	-0.019118
EBPL	-0.019102
IGF2BP1	-0.019100
PSORS1C1	-0.019099
RBMX2	-0.019050
SFI1	0.019035
UBA2	0.018976
CXCR5	-0.018950
PLEKHG3	0.018917
ATRX	-0.018910
SP100	-0.018903
CALHM1	-0.018882
PADI1	-0.018828
ZNF197	0.018825
DRD3	-0.018805
SSH1	-0.018677
DDIT3	-0.018676
OSBPL7	0.018636
MROH2B	-0.018610
HMGN2	0.018579
NAPB	0.018549
WHAMM	-0.018524
ZNF32	-0.018488
ZMYM5	-0.018437
TSHZ2	0.018437
FBXO4	0.018421
MAPK4	-0.018407
PROK2	0.018401
PLEKHF1	-0.018382
ACTN1	-0.018369
WASH7P	-0.018359
ASCL2	0.018338
RPL36AL	-0.018321
GVINP1	-0.018280
SMIM7	0.018268
CHST13	0.018256
SLC15A4	0.018228
AGAP1	0.018228
XPO1	0.018226
PLAUR	-0.018220
PLK3	-0.018139
MAT2B	0.018076
DSTYK	0.018063
SF3B1	-0.018056
DOPEY2	-0.017994
ITM2A	-0.017993
FAM13A	-0.017976
MYOM2	0.017967
SNRPD3	-0.017934
PDLIM7	-0.017926
AMMECR1	0.017869
G3BP2	0.017813
SMAD1	-0.017806
TMEM128	0.017802
PLP2	-0.017798
PI4KAP1	0.017793
PTGS2	0.017782
OSBPL5	0.017740
RSPO3	-0.017740
CENPN	-0.017732
GADD45A	-0.017727
ALG13	0.017698
RNF126P1	-0.017689
TYMS	0.017661
RGMA	-0.017621
MIDN	-0.017593
TNFAIP8L1	-0.017580
INSM1	-0.017534
CRB3	-0.017516
STAP2	-0.017460
PEX6	-0.017453
EFHD2	0.017441
SOX30	-0.017439
NME4	0.017430
NPEPPS	0.017393
ART4	-0.017382
CISD2	0.017375
AKAP7	-0.017373
RPS27	-0.017363
TOX4	0.017352
ABCA2	0.017349
WNT2B	-0.017348
GZMM	0.017342
EMP1	-0.017336
KLRG1	0.017331
NAPSB	-0.017278
SLFN5	-0.017257
APOBEC3F	0.017252
SGK1	-0.017238
ACOT4	0.017230
PSMD1	0.017223
LSP1	0.017221
NAE1	0.017177
WDR33	-0.017176
NGFRAP1	0.017151
OR2W3	-0.017133
ANPEP	-0.017128
MLH3	-0.017127
CLEC12A	-0.017118
SAP30L	0.017115
IL6ST	-0.017108
IDO2	-0.017090
OSBPL5	0.017086
MSH5	-0.017071
CCR6	-0.017053
UBOX5	-0.017051
CAMK4	-0.017049
UGGT1	-0.017046
FAM115C	-0.017045
LMNA	-0.017040
MTERF3	0.017020
PRAMEF5	-0.017019
NBL1	-0.017010
ZNF532	-0.016992
TP53INP1	0.016992
TMEM209	0.016982
ZNF830	-0.016955
ODF2L	0.016948
S100A1	-0.016942
LY6H	-0.016937
SPTBN1	-0.016927
FEZ1	0.016924
CTNNBIP1	0.016920
FAM69A	-0.016906
ZWINT	-0.016898
AGFG1	-0.016879
CD3E	0.016869
CTSG	0.016858
HLA-H	0.016858
THOC2	-0.016856
COL20A1	-0.016822
ERAP2	-0.016820
ACTR10	0.016816
AVPI1	-0.016807
TRIB1	-0.016792
EGR3	-0.016790
CCDC34	0.016778
ZNF365	0.016769
XCR1	-0.016764
LBR	-0.016741
MEGF9	0.016719
USP10	-0.016716
CYP4V2	-0.016702
BSDC1	0.016689
RPL22L1	-0.016678
ZNF135	-0.016675
FAM118A	-0.016658
STAU1	-0.016655
SIGLEC5	-0.016599
VN1R2	-0.016581
SH2D1A	0.016553
PLA2G2D	-0.016550
BAHD1	-0.016542
EPS15	0.016532
CHI3L2	0.016530
FAM98A	0.016530
DHX38	0.016528
ARHGEF15	-0.016516
SS18L2	-0.016499
SLC22A18AS	-0.016493
GOLGA8B	0.016479
TGFBR3	0.016472
IARS	0.016427
CCDC174	-0.016422
NANOS2	-0.016421
SLC2A3	-0.016420
SNORD31	0.016410
AKT1	0.016409
NOC4L	-0.016409
CTSC	0.016387
ZNF333	0.016373
N4BP2	0.016357
LRRC8C	0.016343
STRADB	0.016342
TRIM29	-0.016334
GEM	-0.016324
CCL2	-0.016320
VCPIP1	0.016291
ANKDD1A	0.016290
CLDN18	-0.016277
RORA	-0.016272
SMAP1	0.016263
AZI2	0.016259
PPP1R21	0.016241
COL4A3BP	-0.016234
RNF125	-0.016230
IKZF1	-0.016228
TIAM1	-0.016227
RBM25	0.016209
SLC37A3	0.016195
CLN6	-0.016186
POU5F2	-0.016185
CALML4	-0.016170
CCR1	-0.016168
MON2	0.016164
OR52D1	-0.016160
TNRC6C	-0.016159
BAGE5	-0.016159
ZMIZ1	-0.016155
CCDC86	0.016150
LBH	0.016123
GCA	0.016115
OR2A42	-0.016107
HSD17B12	-0.016099
TMEM214	0.016069
PTGS2	0.016046
ESPL1	-0.016044
ALYREF	0.016038
BCL2L1	0.016031
MTMR4	0.016029
FZD6	0.016027
HM13	-0.016022
GSTM2	0.016021
ARID5A	-0.016013
UFM1	0.016011
LY6E	0.016008
ELMOD3	-0.015998
PDE9A	-0.015993
JUP	-0.015991
DNAJC5G	-0.015975
TRAPPC6B	0.015955
HLA-DRB4	-0.015916
SLC35F2	0.015901
OTUB1	-0.015895
SEPT1	0.015895
TRIT1	0.015889
NAT14	-0.015871
KMT2A	0.015864
WNT7A	-0.015858
SMEK2	0.015841
SPATA7	0.015821
MED23	0.015813
CBL	0.015806
HCFC1R1	-0.015794
NAPEPLD	0.015794
HIST1H2BC	0.015786
OLFM1	0.015780
SPDL1	0.015778
HAX1	-0.015765
GPAT2	-0.015757
TBL1XR1	0.015747
FAM160B1	0.015742
PRKCSH	0.015733
SESTD1	-0.015722
CGB7	-0.015720
PNRC2	0.015714
RP1L1	-0.015710
RPL18A	-0.015710
ANXA11	-0.015695
GTF2I	0.015687
PIP4K2C	0.015685
HCN3	-0.015680
RNU11	0.015671
PRKCB	0.015667
SCN3A	-0.015644
CCDC89	-0.015639
RAI1	0.015633
ZNF10	-0.015619
LILRA5	-0.015609
TNFRSF9	-0.015607
MVB12B	0.015598
TTTY14	-0.015585
STAG2	-0.015577