!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Rattus norvegicus
!organism	Rattus norvegicus
!cell	liver
!perturbation	ibuprofen
!concentration	263 mg/kg
!time	1 d
!end_metadata
LCN2	0.187553
STAC3	-0.131493
CXCL2	0.122856
SLC6A6	-0.112931
ASNS	0.104831
DHRS7	-0.089373
PSAT1	0.081186
DBP	0.079034
NR1D1	0.076473
FGF21	0.073420
A2M	0.071897
OAT	-0.071373
RRM2	-0.071338
NPAS2	-0.070817
LBP	0.067708
EGR1	0.066931
HDC	0.062875
NR1D2	0.061408
SPINK1	0.059961
TMEM2	0.059681
SERPINA7	0.059622
SLC25A25	-0.059214
IL1R1	0.058854
BHMT	-0.058773
LSS	0.057956
HSD17B2	0.057670
CRY1	-0.057085
PHGDH	0.056759
TMEM30B	0.056023
SPSB4	0.055433
ECH1	0.053653
RTP4	0.051476
ACAT2	0.051294
XPNPEP2	-0.050574
UBD	-0.050404
VNN1	0.050243
CD36	0.049686
IGFBP2	0.049669
CRYM	-0.049335
MTHFD2	0.048779
DMXL2	-0.048731
S100A9	0.048467
SALL1	0.048130
OMD	-0.047913
CCNB2	-0.047213
ADH7	0.046709
DSC2	0.046669
ACOT2	0.046625
CLCA2	-0.046497
ARNTL	-0.046182
JUNB	0.045490
INSIG2	-0.045191
CDK1	-0.044245
EHHADH	0.044119
SULT2A1	0.043924
S100A8	0.043452
RAB30	0.043431
TRIM24	0.042950
PLA2G12A	0.042704
CIDEA	0.041812
HSD17B7	0.041661
RCAN1	-0.041581
SDR42E1	0.041514
SCAP	0.041398
NOX4	-0.041291
SQLE	0.040863
MKI67	-0.040083
BCL3	0.039539
PIK3C2G	-0.039465
ISYNA1	0.039250
TCF19	-0.039118
CDCA3	-0.039007
HYLS1	-0.038826
G6PC	-0.038557
GEN1	-0.038105
PKLR	-0.038036
ECT2	-0.037940
EPHX2	-0.037890
CDKN3	-0.037881
TMED3	0.037626
CPT1A	0.037502
SLC13A4	-0.037442
FMO1	-0.037427
BCAR3	0.037323
UBE2C	-0.037108
ALDH1B1	-0.037039
ESM1	0.036972
SPIN1	0.036953
IDI1	0.036783
BUB1	-0.036748
ONECUT1	-0.036723
IFIT2	0.036570
DCN	0.036484
CCNB1	-0.036478
MIOX	0.036212
HERPUD1	0.036192
TRIB3	0.036163
SOCS3	0.036136
PLEKHB1	0.036092
ZFP37	-0.036018
ALAS1	-0.035972
TSKU	-0.035816
CKAP2	-0.035763
IL1RN	0.035576
PPARA	0.035494
CXCL13	-0.035434
PPP1R3C	-0.035358
RNPEPL1	0.035336
ABLIM3	0.035289
STMN1	-0.035267
PHLDA3	-0.035041
ACMSD	-0.034982
ATG16L2	0.034887
ZNRF1	0.034718
SCD	-0.034694
NIM1K	-0.034389
MCM6	-0.034350
SLC39A14	0.034259
SEZ6	-0.034154
IL13RA1	0.034131
SLPI	-0.034040
NUSAP1	-0.033929
KYNU	-0.033922
GADD45A	0.033522
CCDC126	-0.033285
ALDH1A1	0.033260
FKBP11	0.033134
PYCR1	0.033047
SLC7A7	0.032919
IGFBP1	0.032881
DIO1	-0.032872
LURAP1L	0.032832
CCND1	-0.032821
NNMT	0.032737
KLF10	0.032677
PKDCC	-0.032476
CCNA2	-0.032380
ACBD6	0.032097
RBP2	0.031569
PRLR	0.031561
PPP2R1B	0.031355
SLC30A3	0.031323
ETHE1	-0.031277
UNC5CL	0.031172
CREM	-0.031096
ARHGAP18	-0.031069
RMDN2	-0.030971
INHBB	0.030847
GJB2	0.030813
SOD3	-0.030810
CA2	-0.030637
PRC1	-0.030486
GNAT1	0.030313
NFE2	0.030264
CIB2	-0.030262
ACAT1	0.030204
POPDC2	-0.030039
C5	0.029979
STAT3	0.029970
NET1	0.029831
SLC4A4	0.029807
CTGF	-0.029798
LOX	-0.029648
HADHB	0.029463
CAPRIN2	0.029429
IGFBP3	-0.029371
ACOT1	0.029137
TUBB2A	-0.029082
TOP2A	-0.028982
TEF	0.028888
PCOLCE	0.028877
GCKR	-0.028706
FGL1	0.028579
HMGB2	-0.028514
MSMO1	0.028450
CDH17	-0.028354
DECR1	0.028331
WFDC2	-0.028320
SYTL2	-0.028266
ABHD3	0.028188
KIF20B	-0.027939
PRKCDBP	0.027938
XPC	-0.027863
CMTM6	-0.027789
ZNF354A	-0.027722
SLC7A11	0.027578
ENPP1	-0.027567
SDF2L1	0.027521
ACSF2	0.027478
TFR2	0.027357
FNDC3B	0.027348
FAM115C	-0.027291
IFITM3	0.027144
SLC35D2	0.027136
TMCC2	-0.026999
NAB2	0.026955
MVD	0.026940
CYP1A2	-0.026938
CDC25B	-0.026884
NR0B2	0.026883
ETV3	0.026847
SLC25A33	0.026845
TNFSF13	-0.026789
PER3	0.026719
CDKN1A	-0.026495
ASPM	-0.026430
SGK1	-0.026331
TAT	-0.026142
LRTM2	-0.026047
TRIM59	-0.026009
SLC6A9	0.025773
PCSK6	0.025480
PLA1A	0.025474
EFNA1	0.025472
ACAA2	0.025346
HMMR	-0.025309
ACSS2	0.025300
KIF22	-0.025295
ZNF436	0.025243
NQO1	-0.025163
KIAA0430	0.025152
STAP2	0.025033
NTF3	0.025022
RBFA	-0.025007
LGALSL	-0.024928
AIG1	0.024911
CYFIP2	-0.024901
CCRN4L	-0.024889
SPC25	-0.024887
BAMBI	-0.024861
AQP1	-0.024826
CEBPG	0.024778
TFRC	-0.024738
GGH	-0.024718
CGN	-0.024673
CPNE8	0.024653
RNF144A	-0.024602
PPP1R3B	-0.024602
GDE1	0.024590
ALPL	0.024571
VWA8	0.024520
CYP2U1	-0.024468
SLC34A2	-0.024463
RAPGEF4	0.024422
RPRM	-0.024386
FMO3	-0.024361
FKBP4	-0.024360
GCNT2	0.024344
RAD51	-0.024327
NUF2	-0.024321
ACOT4	0.024247
PIK3R1	-0.024222
CYP8B1	0.024203
GSS	0.024154
SULT1C2	0.024074
THUMPD1	-0.024072
HSD3B1	0.023978
EBP	0.023953
NFKBIZ	0.023951
EIF4EBP1	0.023924
EVA1A	0.023862
SPON2	-0.023843
LTB	0.023752
SLC3A1	-0.023632
NCAPD2	-0.023605
MLEC	0.023548
SLC3A2	0.023454
LIPC	-0.023400
SPIDR	0.023398
SEC11C	0.023366
SLC22A5	0.023283
LRAT	-0.023255
SLC1A4	0.023225
SLC30A1	0.023198
MVK	0.023154
MRO	-0.023147
AGXT	0.023125
PLIN2	-0.023054
ARHGEF19	-0.023011
DDIT4	0.022988
HDAC2	-0.022966
PTPN3	0.022959
KIFC1	-0.022955
CHKA	-0.022948
PRIM1	-0.022925
CENPF	-0.022919
UTP20	-0.022909
ATP8B1	0.022821
ELOVL5	-0.022801
SLC38A7	0.022800
ZDHHC23	-0.022797
PRAF2	-0.022795
STARD5	-0.022775
ILDR2	-0.022752
PABPC4	0.022717
CDC42EP3	-0.022705
KIF20A	-0.022695
FRK	0.022688
ISLR	-0.022678
DLGAP5	-0.022636
VEGFB	0.022621
MSRA	-0.022621
GFRA3	0.022582
LYSMD2	0.022549
LAMC2	0.022507
ABCC2	-0.022503
CYP51A1	0.022452
ADAMTS1	-0.022451
H19	0.022426
DAP	0.022366
NAP1L5	-0.022291
ZNF585A	-0.022284
FZD4	-0.022283
IRF1	0.022275
CHAC1	0.022272
TMEM252	-0.022256
RHPN2	0.022255
SDS	-0.022225
RARRES1	-0.022176
HMOX1	0.022156
IFNAR2	0.022142
VIPR1	-0.022124
CA1	-0.022091
ENPP3	-0.022089
ECI1	0.022089
JAK3	0.022062
GUCY2C	0.022058
ULK1	0.022038
TYMS	-0.021972
OGN	-0.021967
DGUOK	-0.021935
ODF3B	-0.021884
IFIT1B	-0.021843
MMP15	-0.021802
NDE1	-0.021730
TGM1	0.021724
PRSS23	-0.021712
GLT8D1	0.021699
CD63	0.021698
H6PD	0.021679
CRELD2	0.021673
ENC1	0.021604
EPRS	0.021568
TMEM176A	0.021535
ABCA1	0.021485
CCBL1	0.021481
RACGAP1	-0.021448
ESR1	-0.021408
SCRN1	-0.021341
MARVELD1	0.021332
KLHL7	-0.021302
COBLL1	0.021262
PYCARD	-0.021234
LRRK1	-0.021233
RNF8	-0.021207
HMGCS1	0.021173
KIF18B	-0.021112
NAGK	0.021043
ASS1	-0.020981
C9	0.020979
N4BP2L1	0.020974
SSR4	0.020954
CES1	-0.020949
YARS	0.020945
SLC45A3	-0.020933
ABCC3	0.020925
KLHL24	0.020922
SCARB1	0.020911
UHRF1	-0.020900
AURKA	-0.020883
GMPPB	0.020775
SBNO2	0.020741
ADSSL1	-0.020729
MARS	0.020720
ABCG8	0.020697
MFAP4	-0.020614
ALAS2	-0.020601
KLF9	0.020577
SLC7A5	0.020556
EVC	-0.020548
C1QTNF1	0.020504
FABP12	0.020492
CENPK	-0.020462
NUP62	-0.020445
RPA1	-0.020427
MME	-0.020239
ADAM9	0.020230
HERC6	0.020226
CITED2	-0.020220
CDCA8	-0.020166
SLC25A42	0.020160
CEP70	-0.020159
MAGIX	-0.020148
PTPN21	0.020135
DLAT	-0.020064
DMGDH	-0.020062
HSD11B2	-0.020053
LAMP5	0.020019
TMEM258	0.019939
R3HDM2	-0.019921
SLC25A20	0.019884
SNED1	-0.019857
CALU	0.019835
ZMIZ2	-0.019828
ZNF189	-0.019807
YPEL2	0.019782
ACOX1	0.019768
CCL5	-0.019728
CARS	0.019673
HHEX	-0.019662
ATP2B2	-0.019661
PSPH	0.019650
PYGL	-0.019626
OAF	0.019555
DNAJB9	0.019547
GRAMD3	0.019547
RRS1	-0.019520
CKS2	-0.019487
LARS	0.019484
CHIC1	-0.019461
SERPINE2	-0.019460
TBC1D8B	0.019450
REEP6	0.019434
TBCCD1	0.019421
RBP1	0.019419
TMEM159	-0.019410
SLC7A1	0.019405
MARCKSL1	-0.019390
HOXB6	-0.019383
GPR146	0.019338
ORMDL2	0.019315
LNX2	-0.019282
MYO18A	0.019259
TJP3	-0.019258
EGF	-0.019246
ERBB3	0.019218
CSRP1	-0.019206
PCK2	0.019189
PFKFB1	-0.019171
FAT4	-0.019148
DPH5	-0.019106
GAS6	0.019104
TTC21B	-0.019097
EDNRA	-0.019072
FGA	0.019069
RRM1	-0.019067
EDEM2	0.019009
DUSP1	-0.018929
CTSE	-0.018918
HAL	-0.018914
UCP2	-0.018905
TIFA	0.018879
ADH1C	0.018759
CFHR1	0.018753
PBK	-0.018745
SIK2	0.018743
SPAG5	-0.018730
KRTCAP2	0.018687
PSTK	-0.018665
NID2	-0.018659
ABHD5	0.018607
RPS12	0.018603
GADD45B	0.018603
TEX15	-0.018598
CPQ	-0.018592
IRAK3	0.018585
FNIP1	0.018575
MIA3	0.018552
ABHD2	0.018518
SSR1	0.018451
CYB561	0.018431
ACACB	0.018427
SLC39A7	0.018416
MMD2	-0.018414
HINT2	0.018412
MPI	-0.018406
SYVN1	0.018361
DDC	-0.018343
SCARB2	0.018327
PIM2	-0.018324
SLC16A13	-0.018317
AURKB	-0.018296
PPM1K	0.018293
ABCG2	0.018281
DNAJC19	0.018276
TFCP2	0.018247
MPC1	-0.018247
SLC28A2	-0.018245
DDX10	-0.018238
ABRACL	0.018229
GGCX	0.018226
ACSM5	0.018212
FBXO31	0.018183
AXIN2	-0.018165
HYOU1	0.018082
HAUS4	-0.018070
SERPINA10	0.018064
PTEN	0.018062
CETN2	0.018049
ALDH1L1	-0.018025