!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	NICKEL
!smiles	[Ni]
!pubchem_cid	935
!cell_type	Skins biopsies from nickel-allergic patients whose skins were exposed to nickel - 96 hours
!organism	human
!end_metadata
PRR9	0.106328
TCHH	0.090772
SELE	0.089857
KRT27	0.088262
KRT25	0.082656
GZMB	0.079496
KRT71	0.072854
TNFAIP6	0.071550
SELL	0.070616
MMP12	0.070327
PLA2G2A	0.068710
KLRB1	0.066233
CCL18	0.064805
CD69	0.060701
PLAC8	0.056248
IL7R	0.053237
KRT85	0.050445
CXCL9	0.050324
FOS	0.050273
TPPP3	0.049786
CH25H	0.047360
MT1M	0.046305
CD2	0.046193
KRT35	0.046159
CXCL10	0.044724
CD52	0.043996
S100A3	0.043892
CYTIP	0.043541
TRBC1	0.042843
KRTAP9-4	0.042281
CRIP1	0.042052
KRTAP3-3	0.041931
GSTT1	-0.041905
MIR155HG	0.041300
GNLY	0.041174
HLA-DQA1	-0.040851
SASH3	0.040796
AKR1B10	0.040796
STEAP1	0.040333
SUCNR1	0.039992
CCL13	0.039826
GZMA	0.039707
ITK	0.039422
CCL17	0.039313
ANXA1	0.039289
LCN2	-0.038697
CCR7	0.038555
LRP4	-0.038309
CCR1	0.037699
CXCR4	0.037658
APOD	-0.037618
CORO1A	0.037368
GPR171	0.037342
IFI30	0.037095
IRF1	0.037020
UAP1	0.036842
COCH	-0.036598
IGJ	0.036246
CD3D	0.036189
C1orf162	0.036153
GMFG	0.035917
CLEC4A	0.035653
GFPT2	0.035479
KRTAP2-2	0.035091
GPR65	0.034770
VANGL2	-0.034570
KRT15	-0.034361
C2orf40	-0.034343
NNMT	0.034160
FAT2	-0.033910
KRT74	0.033681
LOC100507397	-0.033494
KRTAP1-5	0.033471
FCGR1B	0.033013
CD97	0.032865
VSIG4	0.032808
TRAC	0.032721
COTL1	0.032427
IFIT1	-0.032397
VMP1	0.032382
CCL20	-0.032348
C12orf5	0.032208
CCL19	0.032007
FCER1G	0.031569
SCGB2A1	0.031534
KRTAP11-1	0.031525
GZMK	0.030997
NOV	0.030667
RHOH	0.030652
P2RY8	0.030631
IL32	0.030434
CYP4F8	-0.030430
TIMP1	0.030399
CLCA4	0.030375
C1QB	0.030304
PRKCQ	0.030180
CD1C	0.030021
LCK	0.030003
GBP1	0.029997
LCP1	0.029904
PANX1	0.029697
TRABD2A	0.029603
FOSB	0.029581
MIR21	0.029562
FCN1	0.029483
CCL27	0.029422
THY1	0.029356
WIF1	-0.029133
GPR183	0.029110
SLC47A1	-0.028949
DNM3OS	-0.028647
NDUFA4L2	-0.028629
C16orf54	0.028601
COL6A6	0.028562
CLEC10A	0.028562
KRTAP1-1	0.028502
ZC3H12A	-0.028366
SRGN	0.028364
CXCL11	0.028257
MRC1	0.028078
BATF3	0.028026
EVI2A	0.028007
CCDC146	-0.027994
MYADM	0.027988
EMX2	-0.027981
CD3G	0.027858
CD48	0.027803
NYNRIN	-0.027751
VCAM1	0.027734
RASSF2	0.027567
PNLIPRP3	-0.027555
FBN1	0.027494
LOC284023	-0.027459
CCL21	0.027455
FERMT3	0.027447
ARHGAP15	0.027405
CCL26	0.027385
RAC2	0.027324
TAPT1-AS1	-0.027319
FABP7	-0.027282
ITGA4	0.027279
ACKR3	0.027255
NLRC3	0.027255
POU2F3	-0.027178
PTPRZ1	-0.027112
PPP1R13L	-0.027023
EMP3	0.026745
HCK	0.026614
IL10RA	0.026597
TMEM71	0.026538
CST7	0.026454
PCOLCE2	0.026444
IL2RG	0.026395
GALNT15	0.026390
TMEM159	-0.026353
PIK3C2G	-0.026285
ZNF750	-0.026170
IGSF6	0.026153
LGALS2	0.026111
PSMB10	0.025999
LTB	0.025944
CYP3A5	-0.025935
SDF2L1	0.025842
FAM150B	0.025817
S100A10	0.025798
RFX2	0.025749
FPR3	0.025722
GRAMD1C	-0.025699
PDPN	0.025660
PTGDS	-0.025551
PNP	0.025520
TARP	0.025514
ALOX5AP	0.025456
ICAM3	0.025416
HTRA3	0.025406
NEURL2	0.025391
RAPGEFL1	-0.025326
VIPR1	-0.025307
MIR210HG	-0.025246
ALOX15	0.024988
PI15	0.024930
LOC653602	-0.024904
LOC100287497	-0.024722
CD37	0.024714
DOK2	0.024679
BIN2	0.024630
SAMSN1	0.024612
DCT	-0.024612
C1QC	0.024582
PILRB	-0.024531
EHF	-0.024446
CCL5	0.024441
LINC00969	-0.024420
XCL1	0.024377
GABRE	-0.024362
NCEH1	0.024349
ACKR4	0.024336
ADAM1A	-0.024327
PLP1	-0.024324
PCP4L1	-0.024271
SCUBE2	-0.024214
KRTAP4-6	0.024179
KRTAP9-3	0.024173
KRTAP4-1	0.024143
MIR181A2HG	-0.024142
RSAD2	-0.024129
HMHA1	0.024111
WARS	0.024034
CAMSAP3	-0.023937
CMA1	0.023912
NAPSB	0.023912
STAT1	0.023881
IRX3	-0.023814
FAIM3	0.023800
GLIPR2	0.023690
FABP4	0.023656
TYROBP	0.023548
LINC01002	-0.023534
SH2B3	0.023504
ODC1	0.023441
SHISA2	-0.023405
GBP3	0.023327
SCN4B	-0.023316
KRTAP17-1	0.023312
CCDC109B	0.023252
CYFIP2	0.023200
HLA-DRB4	0.023125
HCLS1	0.023095
CTSL	0.023061
NPIPB15	0.023029
CDA	-0.022953
ALDH3B2	-0.022923
NDC80	0.022922
TMPRSS11E	-0.022915
LY96	0.022850
A2ML1	-0.022817
PTX3	0.022788
EFS	-0.022765
PHYHIP	-0.022719
CAPN14	-0.022715
TMEM255A	-0.022663
SPRR4	-0.022651
D2HGDH	-0.022570
SLC20A1	0.022553
APOL1	0.022543
KRTAP3-1	0.022479
FXYD6	-0.022459
PMAIP1	-0.022456
STAT4	0.022422
S100A12	0.022394
LYVE1	0.022366
IL18RAP	0.022353
RAB31	0.022307
UCP2	0.022298
FAM65B	0.022257
KRTAP4-3	0.022232
KRT33B	0.022208
SNX10	0.022170
PROCR	0.022128
PTPRC	0.022119
MIR205HG	-0.022105
LOC101928837	-0.022061
TRAT1	0.022055
HPGDS	0.022055
LOC729732	-0.022014
CLIC3	-0.022000
KRT77	-0.021958
LOC284837	-0.021958
ARPC1B	0.021941
SLAMF8	0.021838
PPP1R13B	-0.021834
VCAN	0.021810
MS4A6A	0.021809
CD1B	0.021685
KRTAP4-7	0.021666
PLEKHO1	0.021616
CORO2B	-0.021555
TYRP1	-0.021532
PSME2	0.021490
SAMHD1	0.021483
IL6	0.021305
KRT16	0.021281
KRTAP4-12	0.021277
MS4A4A	0.021274
BCL11A	-0.021261
SUSD2	-0.021241
EVI2B	0.021213
PAMR1	0.021183
HP	0.021176
C11orf80	-0.021152
AGR3	0.021149
CELSR2	-0.021114
EVPL	-0.020998
CAB39L	0.020992
LINC01215	0.020986
COL4A1	0.020975
HEG1	0.020973
RCSD1	0.020944
RNF43	-0.020930
CTSG	0.020928
RUSC1-AS1	-0.020927
FHL1	0.020881
HCST	0.020872
G0S2	0.020816
ARHGAP9	0.020808
DLGAP5	0.020803
BCHE	-0.020681
NCKAP1L	0.020674
IFI44L	-0.020673
VAV3	-0.020583
RAPGEF4	-0.020539
TGM3	-0.020529
HIST1H2AC	-0.020527
CDKN3	0.020498
PLEK	0.020489
PANK1	-0.020444
FCGBP	-0.020393
KLRG1	0.020388
SOCS3	0.020383
MIR22HG	0.020369
TREM1	0.020354
ZNF273	-0.020353
ARHGEF34P	-0.020290
ULK1	-0.020273
CKMT2-AS1	-0.020268
C3AR1	0.020230
SOX9	-0.020207
ICAM1	0.020150
CCR6	0.020146
RASSF6	-0.020142
GPR155	-0.020131
RSRP1	-0.020102
PCAT6	-0.020082
CYR61	0.020078
SNHG24	0.020061
EPHB6	-0.020010
CD33	0.019999
ALOX12B	-0.019973
GATA3	-0.019942
UGDH	0.019939
CYP4F22	-0.019939
DNASE1L2	-0.019902
FDPSP2	-0.019901
MAP4K3	-0.019887
ATP6V1C2	-0.019886
DDX21	0.019882
POMZP3	-0.019859
TYMP	0.019842
S1PR3	0.019806
MSANTD2	-0.019805
SMG1	-0.019791
RELT	0.019777
NDRG4	-0.019770
MMP7	-0.019753
GTSF1	0.019744
ZNF512B	-0.019740
PKD1P1	-0.019735
PSMB9	0.019734
CD1D	0.019732
KLRF1	0.019721
LEP	0.019700
LOC100130987	-0.019685
GRAMD4	-0.019651
ETS1	0.019640
TRIM73	-0.019635
AHSA2	-0.019627
SLA	0.019627
UPP1	0.019622
CD53	0.019617
CARD6	0.019610
LOC100286895	0.019602
KRTAP1-3	0.019587
SHPRH	-0.019563
PPIL4	-0.019543
THEMIS2	0.019542
CD27	0.019537
SFRP2	-0.019496
FYB	0.019479
PLEKHH1	-0.019465
PI3	-0.019409
ACP6	-0.019404
ZNF767P	-0.019380
SLC26A9	-0.019376
TNFSF8	0.019373
CYP4X1	-0.019320
NPHP3	-0.019305
ZFP3	-0.019293
HIST2H2BE	-0.019293
TNFRSF12A	0.019281
EN1	-0.019226
CA2	0.019208
NRROS	0.019203
A2M-AS1	0.019199
KLF5	-0.019162
C17orf58	0.019153
GPR18	0.019126
KRT34	0.019106
APPL2	-0.019077
SOCS2	0.019064
KIF20A	0.019060
ENTPD1	0.019030
ANK2	0.019029
SPOCK2	0.018988
FPR1	0.018987
PM20D1	-0.018965
ZNF177	-0.018920
OLFML2A	-0.018908
THBS1	0.018895
FAM107B	0.018880
PRSS23	0.018801
TUBB6	0.018771
PIK3R1	-0.018733
DOK5	0.018727
CCR2	0.018694
GPR115	-0.018673
FCGR3B	0.018655
CCR5	0.018637
ACVR2A	-0.018631
IL37	-0.018627
TGFBR2	0.018627
UBE2QL1	-0.018626
CPXM1	0.018580
BCAR3	-0.018558
CHMP4C	-0.018490
LY6G6C	-0.018489
HSPA2	-0.018454
OSMR	0.018434
RC3H1	-0.018399
SERPINE1	0.018355
MTERF2	-0.018306
SYT17	-0.018298
RNASE7	-0.018281
SLC19A2	-0.018276
CFP	0.018274
TTK	0.018273
CSF2RB	0.018245
CTAGE9	-0.018225
KRT80	-0.018195
CCL2	0.018192
TNC	0.018189
ITGB2	0.018180
STEAP4	0.018177
CYP1A1	-0.018158
HOXA5	-0.018120
AMICA1	0.018088
MS4A7	0.018082
KIAA0907	-0.018073
MFAP5	0.018055
CD163	0.018048
ISG20	0.018045
C15orf48	-0.018045
RNF128	-0.018040
IFI44	-0.018036
RARRES3	0.017996
GTF3C6	0.017961
HERC5	-0.017951
NPIPA1	-0.017906
IGSF9	-0.017876
PHGDH	-0.017853
C11orf52	-0.017833
PDZK1IP1	-0.017798
SDC2	0.017795
C3orf52	-0.017773
YPEL3	-0.017768
TP53I3	0.017752
CENPW	0.017749
KMO	0.017746
NCF2	0.017693
ZBTB48	-0.017678
SYTL1	-0.017640
HS3ST6	-0.017604
CREB5	0.017601
FNBP1L	-0.017585
IL11RA	-0.017585
PTPRF	-0.017584
GRHL1	-0.017575
CARD18	-0.017557
ELOVL3	-0.017551
GPR133	0.017549
NAMPT	0.017549
OXNAD1	0.017504
LAP3	0.017500
KRTAP9-8	0.017475
ITPKC	-0.017425
SPRY2	-0.017403
ACOT9	0.017399
ZNF266	-0.017391
DLX5	-0.017382
C1QTNF2	0.017373
C1QA	0.017366
SDHAP2	-0.017338
ERP27	0.017328
SH3BGRL3	0.017317
CDC42EP2	0.017314
RPP40	0.017287
ZNF514	-0.017286
CALU	0.017270
SERPINE2	0.017256
ELMO3	-0.017243
GPRASP1	-0.017223