!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	PLX4032
!drugbank_id	DB05238
!cell_type	COLO829 human melanoma cell line-MITF Knockdown (BRAFV600E mutated)
!organism	human
!end_metadata
MRGPRX4	-0.088581
ANGPTL7	0.084243
SPRY4	-0.076870
KCNJ13	0.076034
ETV4	-0.074481
APLNR	-0.067255
SERPINB2	-0.066118
GRAMD1B	-0.064021
TM4SF1	-0.062526
DCSTAMP	-0.060971
SERPIND1	-0.060632
INHBA	-0.060465
CRLF2	-0.058041
HPGD	0.057329
CPN1	-0.053949
HTR2B	0.053503
ASPA	0.051739
TESC	-0.051678
KCNG4	-0.051392
SERPINB10	-0.051020
TYRP1	0.050356
CEMIP	-0.049964
SLC27A3	-0.048326
ETV5	-0.048116
SHISA2	-0.047864
CCDC146	0.047562
BMF	0.047431
PAPSS2	-0.046968
DPYSL3	0.046308
STC1	-0.046183
OLFML2B	0.046047
BEST1	0.045918
STK32A	0.045734
CYP24A1	-0.045485
KCNS3	0.045477
LONRF3	-0.044423
MUC13	-0.044137
ATL1	0.043832
JUN	0.043694
PRUNE2	0.043542
NTRK1	-0.043360
RGS5	-0.043050
AREG	-0.042465
ARHGEF3	0.042075
TMEM229A	-0.041491
KCNQ5	-0.041042
TLR4	-0.041023
ST3GAL1	-0.040746
NOV	0.040551
ADAMTS9	-0.040434
ABI3BP	0.040381
TRIM51	-0.039632
FAM129A	0.039609
ADAMTS1	-0.039405
DLX5	0.039185
SYTL5	-0.039111
DUSP5	-0.039096
DACT1	0.039026
CXCL8	-0.038750
FOXD3	0.038603
EGR1	-0.038442
MILR1	-0.038433
KIAA0040	-0.038244
HGF	-0.038170
PRELP	0.038149
PDE5A	0.038129
MAGEL2	0.038109
ZNF536	0.037976
OLFML2A	0.037975
LRRTM4	0.037953
SH2B3	-0.037729
SNAI1	-0.037623
MATN2	0.037507
SPRY1	-0.037409
CMTM5	0.037377
FLRT1	0.037347
CORO2B	-0.037320
CDC6	-0.037271
UBD	0.037237
DUSP6	-0.036906
SEMA6A	0.036815
SESN3	0.036624
LYST	0.036505
ACAN	0.036457
TMOD2	0.036367
ANGPTL4	-0.036323
TRIB1	-0.036119
SHC4	0.036080
HK2	-0.035868
KCNN4	-0.035717
ITGA2	0.035714
JAG1	-0.035712
CNTRL	-0.035671
SLC16A6	-0.035568
CEACAM1	-0.035465
TP53INP2	0.035319
FAM131B	-0.035258
LIF	-0.035242
TGM2	-0.034938
FLRT2	-0.034903
P2RX7	0.034884
UCN2	-0.034859
CRYAB	0.034842
CTGF	-0.034728
PTGS2	-0.034672
PLN	-0.034667
SULT1B1	-0.034640
LINC00341	0.034516
RAPGEF4	-0.034511
SMAGP	-0.034263
NETO2	-0.034248
EGR3	-0.034199
MIR503	0.034162
FHDC1	0.033792
IGFBP3	-0.033675
ARHGAP29	-0.033604
TGFA	-0.033584
FAM222A-AS1	-0.033422
LINC00326	-0.033392
ABHD17C	-0.033128
GEM	-0.033083
ETS1	0.032557
NAALADL2	0.032512
FOXN3	0.032499
ST6GALNAC2	0.032343
SLC35F1	0.032301
SYT11	0.032247
CDK14	-0.032200
C12orf60	0.032138
SYNE3	0.032057
C1orf198	0.031934
HMGA2	-0.031912
MCC	0.031867
MCM10	-0.031844
PNP	-0.031669
ADHFE1	0.031610
RNF157	-0.031465
LINC00277	-0.031465
MAP3K5	-0.031285
CABLES1	0.031200
ZNF608	0.031161
IL27RA	-0.031134
ANO4	-0.031051
ARHGAP24	0.031003
ZEB1	-0.030982
FSTL5	0.030934
GRB14	0.030766
SEMA3A	-0.030731
CHRNA6	-0.030705
B3GNT5	-0.030635
ADAMTS15	0.030469
KAT2B	0.030432
CNTN6	0.030366
FAM19A2	-0.030292
PMAIP1	-0.030146
LPL	-0.030014
PLCB4	-0.029990
STAMBPL1	-0.029975
JAKMIP2	0.029951
PFKFB4	-0.029757
CENPK	-0.029750
LEF1	-0.029665
KLF11	0.029643
AGPAT9	-0.029599
INSC	0.029591
FGFBP2	0.029519
CSPG4	-0.029474
PDE3A	-0.029245
ERRFI1	-0.029239
EIF4EBP1	-0.029230
COL4A3BP	0.029229
ACTN1	-0.029194
PDK1	-0.029119
ANKS1A	-0.029023
SLC25A15	-0.029021
FAM63A	0.028985
CXCL11	-0.028830
AHNAK	0.028795
LRRC8C	0.028727
ENOX1	0.028698
FAM198B	0.028637
MANSC1	-0.028624
TRAF1	-0.028608
ACPP	-0.028603
CDC45	-0.028528
CRYL1	0.028502
RRM2	-0.028487
NAV2	0.028399
PLXNB1	0.028391
SLC20A1	-0.028342
PHLDA2	-0.028331
FOSL2	0.028306
FGL2	0.028246
NGFR	0.028162
PTHLH	-0.028154
SYT14	0.028063
HDAC9	0.028028
PCDHB10	0.027995
EXO1	-0.027915
HIST1H2BB	-0.027910
KCNMB4	0.027909
EFNA5	-0.027892
LURAP1L	0.027884
ADM	-0.027872
IFITM10	0.027753
AMOTL2	0.027734
ALCAM	0.027733
FAM107B	-0.027688
RNF122	0.027563
LANCL3	-0.027493
POLE2	-0.027376
ZNF280A	0.027368
TCN1	0.027363
C12orf76	0.027328
CXCL10	-0.027324
ITPR2	-0.027323
PIK3C2B	0.027253
SLC8A1	0.027138
CA8	0.027105
DUSP22	0.026998
RHOBTB1	0.026990
FGFRL1	-0.026977
CCDC80	0.026972
MPZ	0.026962
PGM2L1	0.026961
EYA4	-0.026908
PTX3	-0.026882
NPAS2	-0.026843
DTL	-0.026561
HSPB8	0.026541
SUCNR1	-0.026539
PCDHB11	0.026491
TFRC	-0.026463
NIPAL1	-0.026349
LINC00189	-0.026344
RSAD2	-0.026329
DHCR7	-0.026326
PDZRN3	0.026315
SLC7A1	-0.026303
POLR3G	-0.026280
FAM189A2	0.026258
HIST1H4H	0.026241
IL24	0.026205
CCNE2	-0.026153
ADAMTS6	-0.026146
SORT1	0.026144
SGCD	0.026109
SLC25A37	-0.026067
FIGN	0.026064
VTRNA1-3	-0.026001
ACTBL2	-0.025995
IL11	-0.025957
SOX4	0.025954
CCND1	-0.025953
TSPAN15	0.025933
DNMBP	-0.025931
GALE	-0.025916
UNC13A	-0.025916
HERC5	-0.025889
TICRR	-0.025837
SEMA7A	-0.025833
LINC00518	0.025828
MR1	0.025819
IL34	0.025737
OLFM2	0.025681
SNORD78	-0.025672
RERG	0.025659
ATP11A	-0.025564
FAT4	0.025504
PIR	0.025474
MAF	0.025462
C16orf52	-0.025459
GPR4	-0.025425
CYFIP2	0.025406
EBF1	-0.025335
MYC	-0.025331
C3AR1	-0.025294
MLKL	-0.025292
ADARB1	0.025290
RASSF4	0.025287
PCDHB15	0.025259
PCDH9	-0.025190
HMOX1	0.025102
COBL	0.025101
LRRC17	-0.025079
SLC30A4	0.025066
RAB30	0.025025
PITPNM2	0.025017
MTUS1	0.024980
INPP5F	-0.024884
SLC7A11	-0.024864
LRRC75A	0.024797
CERS4	0.024747
AMZ2P1	0.024746
IER3	-0.024683
RNF19B	0.024666
LONRF2	-0.024622
DDIAS	-0.024591
CARD16	-0.024573
SRPX2	0.024539
TLCD1	-0.024493
COTL1	-0.024398
SLC45A2	-0.024389
EVI2A	0.024367
HCN1	-0.024341
RPL22L1	-0.024250
IL1B	-0.024238
RASA2	-0.024236
CDKN2B	-0.024215
KLF13	0.024190
ANKRD29	-0.024175
MOB3B	0.024156
MFAP3L	0.024104
TRIM16	0.024092
ARSE	0.024025
PIK3IP1	0.023958
SPRY2	-0.023913
RDH8	-0.023886
FAM84B	-0.023885
GINS2	-0.023862
RUNDC3A	0.023841
DNAJB5	0.023821
TMEM117	0.023803
PCDHB8	0.023778
PTPN21	0.023745
FAM180A	-0.023734
OLIG2	-0.023596
EPAS1	0.023516
HOXB9	-0.023449
OTOL1	0.023426
CHST3	0.023399
AHCYL2	0.023362
STK17A	-0.023314
TIAM1	0.023288
CTHRC1	-0.023272
ARHGAP6	-0.023236
PCDHB18	0.023182
CLSPN	-0.023128
ITGA10	-0.023121
CCDC92	0.023071
AGMO	-0.023071
HIST1H1A	-0.023065
ITPRIP	-0.023043
CCL2	0.023008
LIMK2	0.022984
TNS3	0.022980
HIST1H2BM	-0.022975
PCDHB14	0.022949
HSPA12A	0.022909
HIST1H1B	-0.022895
ERCC1	-0.022889
MFSD2A	-0.022877
BLM	-0.022854
STX7	0.022834
PCDHB9	0.022749
HIVEP3	-0.022717
CD200	-0.022694
STATH	-0.022689
LPAR1	0.022686
PPAT	-0.022635
SLC26A2	-0.022611
NREP	0.022610
SFXN2	-0.022576
EDIL3	0.022571
CST1	-0.022538
MIR503HG	0.022533
GJA3	0.022529
PAX3	0.022515
LSAMP	0.022507
UCK2	-0.022503
GALNT3	0.022496
KLHL24	0.022461
AKAP7	0.022458
GYG2	0.022400
TTLL7	0.022390
FMO4	0.022387
ATF3	0.022351
STXBP6	0.022347
FAM53B	0.022331
SERAC1	0.022327
STIL	-0.022319
PPFIBP2	0.022316
JUP	0.022309
IRAK4	0.022301
MOXD1	0.022236
TNFSF13B	-0.022228
TOX	0.022218
NT5E	-0.022194
NOL6	-0.022185
PPM1L	0.022175
SH2D2A	-0.022157
ANGPT1	-0.022131
POLR1B	-0.022080
TMEM158	-0.022038
LRGUK	-0.022037
DIAPH2-AS1	-0.022018
EPB41L4A	0.022014
TMTC2	0.021979
SLC6A15	-0.021969
CD9	0.021965
CDCA7	-0.021920
LGR4	0.021919
RWDD4	-0.021884
AMD1	-0.021829
SLC2A1	-0.021787
PCDHB7	0.021752
DOT1L	-0.021719
CNTN1	0.021707
PCDHB13	0.021693
MAN1A1	-0.021688
ADAMTS17	0.021684
ATP7A	0.021676
LPHN3	0.021666
CDH7	0.021660
DLGAP1-AS1	-0.021648
KEL	0.021645
WDR76	-0.021643
MEGF9	0.021623
RFTN2	0.021590
CDK1	-0.021543
DSCC1	-0.021526
MIR15A	0.021513
SHROOM3	-0.021476
FAM69A	0.021439
AK4	-0.021439
PCDHB12	0.021349
PLEKHA1	0.021322
CCDC126	0.021301
SEMA3D	0.021279
CTPS1	-0.021254
COL5A2	0.021251
CSGALNACT1	-0.021230
SEMA3C	0.021173
KRT18	-0.021164
IQGAP2	0.021155
CHAMP1	-0.021112
NOC3L	-0.021079
PDLIM4	-0.021074
KIF20B	-0.021046
CDC25A	-0.021024
SFXN1	-0.020989
PPARGC1A	0.020941
FAM126A	0.020912
ELOVL6	-0.020904
ETNK2	0.020895
FANCL	-0.020892
FST	-0.020856
PPAP2A	0.020853
MOCOS	-0.020845
PLA2G6	0.020841
BAIAP2L1	-0.020829
LMCD1	-0.020823
FRMD8	-0.020812
ZNF713	0.020790
GRAMD3	0.020778
CELSR2	0.020773
TP53I3	0.020770
PRKD1	0.020764
CX3CL1	-0.020761
FAM210A	-0.020753
CDCA5	-0.020717
SIPA1L2	0.020713
DIP2B	0.020692
MAPK10	0.020688
C10orf10	0.020687
SOBP	-0.020603
FCGR2A	-0.020513
PKIA	0.020509
TLN2	0.020507
ZMAT3	0.020484
ADD3	0.020481
SH3D19	0.020477
NKAIN4	0.020461
SLC23A2	0.020458
SIX1	-0.020450
MAN2A2	0.020431
ADAT2	-0.020416
PDE3B	-0.020407
DKC1	-0.020389
DCT	0.020377
PHACTR2	-0.020357
ADAM19	0.020325
CEP70	-0.020317
MINPP1	-0.020316
NFKBIA	0.020288
NOLC1	-0.020257
TRAK1	0.020244
MEF2C	0.020197
PCDHB5	0.020196
SLC24A3	-0.020127
LOXL4	-0.020117
PDSS1	-0.020102
CPT1A	0.020086
IFT81	0.020072
LXN	-0.020052
LBH	0.020047
PVR	-0.020017
DOPEY2	0.020015
MCM4	-0.020011
MTHFD2	-0.019990