!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Rattus norvegicus
!organism	Rattus norvegicus
!cell	heart
!perturbation	rofecoxib
!concentration	775 mg/kg
!time	3 d
!end_metadata
S100A9	0.117961
S100A8	0.115298
FOSB	-0.107870
DBP	0.101479
EGR1	-0.090607
NR1D1	0.089238
FOS	-0.087712
ALB	0.086060
PDK4	0.081297
RHOBTB1	0.079141
NFIL3	-0.078155
FAM46B	0.073624
NR4A1	-0.069814
ARNTL	-0.068527
ANGPTL4	0.067565
C2CD4B	-0.064285
PLA2G4A	0.063955
FKBP5	0.063464
PHLDA1	-0.063129
IER3	-0.061070
FAM117B	0.059560
TCAP	0.058698
RRAD	-0.057916
NR1D2	0.056840
CXCL2	-0.056078
MYC	-0.052557
REV3L	-0.051882
ZFP36	-0.051583
FMO3	0.051027
RAPGEF5	0.050762
CYP2E1	0.050621
CRYL1	-0.050013
CYB561	0.048531
FMO2	0.047207
ERRFI1	-0.047183
NPAS2	-0.047115
TINAGL1	0.046473
PER3	0.046351
G0S2	-0.046313
MGST2	0.046048
BTG2	-0.045683
FAM111A	-0.045661
CRISP2	0.045398
DUSP5	-0.044403
CBLB	0.044401
PPL	0.043707
SMIM5	-0.043161
LGALS3	0.043014
ARRDC2	0.042970
TNFRSF12A	0.042756
MYL7	0.042311
COMT	0.042207
XDH	0.042108
CYR61	-0.042049
TEF	0.041967
DUSP1	-0.041897
EFHD1	-0.041680
PITX2	0.041149
GATA5	-0.040951
AKR1B10	0.040927
OSBPL3	0.040743
LMCD1	0.040738
TSPAN18	-0.040026
HMGCS1	-0.039422
ARID5B	-0.039156
KLHL40	0.038984
CPA6	0.037942
LRRC10	-0.037889
HPD	0.037616
PPARGC1A	-0.037480
SESN1	0.037376
HS3ST5	0.037165
XIAP	-0.036922
KLF10	0.036667
ATF3	-0.036314
PGC	-0.036038
PHACTR3	0.035864
RBM3	0.035766
EYA2	0.035506
FMOD	0.035360
PKDCC	-0.034988
ODF1	0.034943
RND1	0.034873
CRY1	-0.034715
HP	0.034702
PDGFA	-0.034611
SLC38A2	-0.034554
LRCH1	0.034533
GTF2IRD1	-0.034265
FGF9	-0.034031
GPM6A	-0.033938
THBD	-0.033931
PTPLB	-0.033884
NCAPG2	-0.033686
SERPINB1	0.033591
CITED1	-0.033577
PIM3	0.033537
ADAMTS15	0.033384
RREB1	-0.033351
NAP1L5	-0.033332
PRKACB	-0.033330
ADAM19	-0.033200
ACER2	0.033147
PLA1A	0.033126
TFRC	-0.033093
SLC7A13	0.033091
BCL6B	-0.033051
BHLHE40	0.032981
KCNJ12	-0.032953
REG3G	0.032796
ICAM1	-0.032741
VASP	-0.032699
TPPP	-0.032634
MUM1L1	-0.032555
P2RX5	0.032509
EPHX1	0.032424
SLC39A8	-0.032415
FBXO32	-0.032347
OAZ3	0.032309
FGL2	0.032165
FAR1	-0.032149
PLCL1	0.032097
ADH1C	0.032004
SPON1	0.031613
RIPK2	-0.031574
PTGFR	-0.031434
L2HGDH	-0.031385
SHROOM2	0.031361
IDI1	-0.031360
GADD45G	-0.031328
ANGPT1	-0.030928
AFAP1L2	-0.030773
CD38	0.030708
FRG1	0.030630
POSTN	0.030560
FBLIM1	-0.030499
NAA40	-0.030320
HMOX1	0.030151
GJA1	-0.030138
GSG1	0.029916
DGAT2	0.029911
NR4A3	0.029879
SQLE	-0.029853
DBN1	-0.029724
RUFY3	-0.029641
IGSF3	-0.029607
PENK	0.029583
ANKRD2	0.029536
KY	-0.029478
F3	0.029393
SPHKAP	-0.029326
FZD1	-0.029306
RPRML	0.029225
ALDOB	0.029200
TMEM140	0.029051
HMGCS2	0.029021
KCNA5	0.028994
ASPA	0.028898
ATG10	-0.028878
GABARAPL1	0.028877
MAOB	-0.028760
SOCS6	-0.028730
FHL3	-0.028631
CDC42EP2	0.028545
LRRC8A	0.028435
MRC1	0.028303
KLKB1	0.028214
DNAJA3	-0.028204
ANKRD23	0.028199
PDE4B	-0.028143
FAM102B	0.028119
ELOVL6	0.028112
NUCB2	0.028098
SOX4	-0.028050
DYRK2	-0.028025
CH25H	-0.027988
MYOCD	-0.027929
RTN4RL1	-0.027910
SLC25A30	-0.027805
ALOX5AP	0.027763
KDM6B	-0.027748
SCN3A	0.027744
CCL13	-0.027510
LEO1	-0.027507
EGR2	-0.027465
NLK	-0.027452
FOXO1	0.027393
HIVEP1	-0.027391
NOS3	-0.027388
LRRC4B	-0.027254
RBP7	0.027208
AP1S3	-0.027172
REG3A	0.027106
LIMS1	-0.027068
C3	0.026815
WIF1	0.026808
MMD	-0.026723
PCDH20	0.026675
LYVE1	0.026642
HYLS1	0.026626
DUSP26	0.026595
POPDC3	-0.026565
MSMO1	-0.026443
RNF115	0.026324
PLCE1	0.026261
CKAP4	-0.026196
FAM73B	-0.026157
HAO2	0.026125
SERPINA3	0.025916
UCP3	0.025784
BOC	-0.025768
KLF4	-0.025758
CDC42EP4	0.025741
PTGS2	-0.025696
FASTKD5	-0.025636
ADAMTSL2	0.025634
CCND1	-0.025611
H6PD	0.025543
CITED2	0.025516
NFKBIA	-0.025455
BCR	-0.025415
FAM107A	0.025398
PPARG	0.025336
LRG1	0.025321
CNKSR3	-0.025316
RAB30	0.025311
FXYD7	-0.025303
DNAJB1	-0.025190
MYOT	0.025168
IKZF2	0.025143
MAP3K6	0.025137
TXNIP	0.025089
MLLT11	0.025085
SLC22A3	-0.025064
IGFBP5	-0.024989
SEMA3D	-0.024989
ARMCX2	-0.024908
GDPD5	-0.024886
CYP51A1	-0.024868
RNASE1	-0.024834
BAIAP2	0.024827
PLP1	-0.024826
ADAMTS19	-0.024733
PLLP	0.024730
LILRB4	0.024715
GUCD1	0.024706
B3GNTL1	-0.024700
AKAP1	-0.024664
CD93	-0.024602
SGK1	-0.024579
GDA	0.024562
KCNA4	-0.024514
SLC37A1	-0.024432
IRS2	-0.024378
AADAT	0.024322
TPPP3	-0.024300
FSD2	-0.024285
PBX3	-0.024243
CYP11A1	-0.024234
ASB2	-0.024196
GSAP	0.024171
STARD13	0.024169
TMEM248	0.024162
PIP5K1B	-0.024153
S1PR2	-0.024144
EFNB1	-0.024122
PCDH17	-0.024119
SELE	-0.024108
PIK3R3	-0.024068
PER2	0.024066
CNKSR1	0.023980
HMCN1	-0.023976
ALOX15	0.023920
DCBLD2	-0.023887
CYP4B1	0.023831
MARCKSL1	-0.023804
ATF2	-0.023803
TMEM252	0.023790
CP	0.023778
PALMD	-0.023776
MEX3B	-0.023734
IRAK2	0.023650
FSTL3	0.023573
JUNB	-0.023509
JAG2	-0.023459
HPX	0.023445
RALGDS	-0.023431
PHYHD1	0.023426
SSBP3	-0.023422
EIF3A	-0.023383
RBM47	0.023352
INPP5E	0.023287
APLN	-0.023275
SMYD1	-0.023252
ITGA5	-0.023237
IVNS1ABP	0.023196
GADD45A	0.023130
HDAC5	-0.023089
PLAC8	0.023072
UAP1	0.023060
FLNC	0.023031
ZNF189	0.023031
SQRDL	0.022989
LIPA	0.022963
ATP6V0A2	-0.022944
RYR3	-0.022918
MTM1	-0.022913
MAX	0.022847
PARD6G	-0.022798
PHOSPHO1	-0.022675
MIOX	0.022665
TMEM116	-0.022602
FAM211A	-0.022601
RCOR2	-0.022558
PPAPDC3	-0.022534
MAP3K8	-0.022509
SPP1	0.022501
LRRC14B	-0.022378
CLEC10A	0.022332
NDUFAF1	-0.022253
OSBPL8	-0.022190
SENP7	-0.022163
CARD9	0.022147
ATXN1	-0.022102
SWI5	0.022053
ZNF846	-0.022023
PPP1R13L	-0.022017
HYOU1	-0.022015
BLOC1S6	0.022003
ILF3	-0.022002
CCNB2	0.021985
RNF34	-0.021957
YARS2	-0.021880
ZNF142	-0.021872
IL1R2	0.021855
MEF2C	-0.021839
NUDT19	-0.021831
CLIP2	-0.021818
DCP1B	0.021798
DNAJA1	-0.021797
INIP	0.021772
MUL1	-0.021745
TCP11L2	0.021730
ACVR1	-0.021721
HEY1	0.021687
AK1	-0.021633
PROM1	0.021631
WAC	-0.021621
SDC4	0.021597
BMPER	0.021591
CYP1B1	0.021540
ACSL4	0.021504
KDM8	-0.021473
IRF2BP2	-0.021407
ACSL3	-0.021394
SOBP	-0.021384
SLC46A3	-0.021343
GATSL3	0.021306
MLLT3	-0.021287
CNTNAP1	-0.021278
PLXND1	-0.021236
DUSP8	-0.021208
TRIM8	-0.021191
FAM229B	0.021188
SFPQ	-0.021140
RASAL2	0.021041
DUSP15	0.021015
BANP	-0.021010
SBK1	-0.021005
CBFA2T3	-0.021004
ABHD2	0.020986
RHOB	-0.020981
ADAM17	-0.020952
MMP11	-0.020908
ITGA1	-0.020874
AMIGO1	-0.020869
P2RX4	-0.020856
HRASLS5	0.020841
DENND2C	-0.020828
MEF2A	-0.020799
NEU3	-0.020788
S100A4	0.020741
ACE	0.020719
TOB1	-0.020697
EMCN	-0.020662
PACRG	0.020589
AFAP1L1	-0.020551
PDGFRL	0.020534
GIMAP4	-0.020524
CALCRL	-0.020514
PCDH1	-0.020494
LARP6	0.020458
PCMTD1	-0.020452
RGS2	-0.020409
LIMD1	-0.020404
PPARA	-0.020385
NAPSA	0.020385
ARID3B	0.020363
TBC1D9	-0.020362
PNPLA2	0.020358
CMTM8	0.020337
WDR6	-0.020327
SNCG	0.020325
EHBP1	-0.020300
THBS4	0.020275
TUBA8	-0.020274
FGD1	-0.020271
VEGFA	-0.020226
RFX2	-0.020224
CCNG2	0.020204
JUN	-0.020183
AGPS	-0.020152
ANKRD37	0.020135
DUSP27	0.020129
RPS6KA3	-0.020126
HCST	0.020122
MTHFD2	0.020108
OPN4	0.020085
PGLYRP1	0.020053
USP2	0.020039
EPS8	0.020025
IL6	-0.020003
TRDMT1	-0.020001
SYNPR	0.019985
CXXC5	-0.019976
DGKZ	-0.019960
KLF2	-0.019955
MIS18A	-0.019942
GNA12	-0.019927
TTLL1	-0.019926
GJA3	-0.019922
CIDEA	0.019916
MPPED2	-0.019905
ID1	0.019893
CLDN12	0.019883
MRAP	0.019875
KCTD10	0.019869
CCDC66	-0.019858
NRP1	-0.019853
PYROXD2	-0.019843
MMP15	-0.019816
UHRF1BP1L	0.019782
CMA1	-0.019777
MEX3D	-0.019771
VHL	0.019766
TAGLN	0.019752
ADRA1D	-0.019729
ARID4B	0.019708
SIX4	-0.019701
LNX2	0.019691
HERPUD1	0.019688
TROVE2	-0.019688
OTUD1	-0.019688
LOX	0.019630
TJP2	-0.019627
PANK1	0.019611
KPNA2	-0.019597
WSB1	-0.019590
S100A6	0.019585
PDRG1	0.019547
TUBB2A	-0.019543
MYADM	-0.019541
CXCL10	-0.019532
TMEM177	-0.019522
SH3BGRL	-0.019499
SMAD7	0.019492
UHMK1	-0.019468
ATP8B1	-0.019463
ARL15	-0.019434
NKX3-1	0.019433
FAM208B	-0.019424
MITD1	0.019355
ST3GAL6	-0.019353
CTRL	0.019309
EGLN3	-0.019263
C1QB	0.019245
KLHL4	-0.019204
VBP1	-0.019181
HOMER1	-0.019179
RNF2	-0.019150
SOX18	0.019133
FXYD3	-0.019123
TMEM55A	-0.019120
PFKFB2	-0.019120
TFPI2	-0.019117
CITED4	-0.019114
ITGA6	-0.019084
EEA1	-0.019079
L1CAM	-0.019077
SOCS3	-0.019074
ARHGAP18	-0.019059
N4BP1	-0.019055
STARD3	0.019011
FAM43A	-0.019000
MCF2L	0.018975
PIGR	0.018974
ESM1	-0.018972
SLC25A46	-0.018966
ATG4D	-0.018950
CLCN3	0.018936