!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Estradiol
!smiles	CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
!drugbank_id	DB00783
!pubchem_cid	5757
!cell_type	Uterus - - single injection of 400 ug/kg - 1 Hour after treatment
!organism	mouse
!end_metadata
CEBPB	0.333399
GADD45G	0.223592
CKB	0.203463
ERRFI1	0.175508
RPS19	-0.170709
IER2	0.154467
IER3	0.150317
SOCS1	0.146433
RASD1	0.138296
TIPARP	0.126579
SOCS3	0.121508
PIM3	0.121208
ACTG1	0.119288
RHOU	0.107672
TPT1	0.103449
UBC	0.102933
CEBPA	0.099811
FOS	0.098179
HSD17B11	0.096680
MIDN	0.095647
ALAS1	0.094385
NAB2	0.088589
ZFP36L2	0.087145
YBX1	-0.085689
TAGLN	-0.081636
SLC7A5	0.079700
SOX17	-0.077044
ISYNA1	0.076150
DUSP1	0.075755
TOB1	0.073283
SPSB1	0.071612
CHD4	-0.068922
RPS3	0.068783
PLP2	-0.068557
TUBA1A	-0.068027
RGS3	0.067233
LGALS1	-0.066395
TWIST2	0.066043
F3	0.065874
LSP1	-0.064433
GAS1	-0.062109
BTG2	0.061964
LAPTM4A	-0.059755
HOXA11	-0.058976
RPL3	0.057986
NRIP1	0.057968
RPL19	-0.056411
HMGN1	-0.056049
DYNLL1	-0.055901
MSX1	-0.055889
TUBA1B	-0.055797
WNT4	0.055268
CNN1	-0.055125
ANAPC5	-0.054651
CD164	0.054122
EEF1A1	0.053389
GSN	0.053339
TUBB	-0.052529
MYL12A	-0.052432
TRIM28	-0.051968
ANGPTL2	0.051905
WDR92	-0.051776
ATP1A1	0.050614
RPS10	-0.049841
BTF3	-0.049424
PPIA	-0.048929
ID1	0.048741
ZFP36L1	0.048417
ADRB2	0.048145
RPL10	-0.047634
U2AF2	-0.047485
NDUFA7	-0.047345
RPL13	-0.046840
PRNP	-0.045782
RPL7	0.045738
HIF1A	0.045646
JUN	0.045615
GADD45A	0.045263
PTGES	0.045059
LDHA	-0.044722
VEGFA	0.044452
PNP	0.044284
PRRX2	0.044193
TGFB1I1	-0.044190
RASSF5	0.043400
RGS2	-0.043378
RAC1	-0.043114
ELF3	0.042800
SSRP1	-0.042705
HERPUD1	0.042557
SGK1	0.041182
SNRPD2	-0.041026
RNF10	-0.040765
NR4A1	0.040731
RHOB	0.040618
IRF1	0.040383
TUBA1C	-0.040383
KLF10	0.040191
ANXA6	-0.039850
MARVELD1	-0.039587
PLAT	-0.039268
ACAA2	-0.039115
ARL6IP1	-0.038468
DDIT4	0.038437
TPI1	-0.038360
ERH	-0.038269
TXNIP	-0.038241
ACTG2	-0.038096
RPS24	0.038051
GNAI3	-0.037915
RPL37A	0.037682
CTDSP2	-0.037428
SURF4	-0.037351
RPL5	0.036870
STAT5A	0.036673
SNRK	0.036583
DNAJA1	-0.036109
NDUFS2	-0.035994
PDK4	0.035674
S100A6	-0.035542
HINT1	-0.034946
MAD2L1	0.034881
WBP1	-0.033996
PGF	0.033912
TMEM165	-0.033843
BHLHE40	0.033360
PSMA6	-0.033041
YWHAZ	-0.032843
RAN	-0.032647
MORF4L1	0.032544
LY6E	-0.032100
MKNK2	0.032079
SERPINH1	-0.032067
COL4A2	-0.032060
PKM	-0.032014
CXXC5	0.031958
RABAC1	-0.031937
APCDD1	-0.031931
PSMA3	-0.031910
MARCKSL1	0.031710
HK1	0.031624
CSTB	0.031433
RELA	-0.031271
SPTBN1	0.031155
GAS6	0.031121
MYLK	0.030924
RPS7	-0.030786
FZD2	-0.030757
TLE3	0.030682
PLK3	0.030567
HSPA8	0.030486
COL6A2	-0.030438
ACKR3	0.030344
GNB2	-0.030228
ETS2	0.030006
PQLC3	0.029968
KDELR1	0.029714
ATF4	0.029394
PTGER4	-0.029240
BZW2	-0.028921
MXD4	-0.028588
PLK2	0.028352
CDC37	-0.028196
MYADM	-0.028101
PDXK	0.027922
NDUFV1	-0.027591
CALU	-0.027569
MRFAP1	0.027456
PIM1	0.027335
EGR1	0.027287
SOX18	0.027130
IL17RA	0.027075
CAPNS1	-0.026916
PTOV1	-0.026904
PTPN1	0.026756
TGIF1	-0.026718
RPS2	0.026556
TUBB6	-0.026378
S100A10	-0.026366
ANXA2	-0.026363
GPI	-0.026308
HSPD1	0.026230
BOK	-0.026119
SOX4	-0.025903
PPTC7	0.025823
GDF15	0.025815
RPS27A	0.025774
BSG	-0.025718
SRSF2	0.025483
EMP1	-0.025432
APOA1BP	-0.025412
COL6A3	-0.025330
BDKRB1	0.025314
ARF1	-0.025269
PCNP	-0.025223
IFITM3	-0.025222
INHBB	0.025212
COL1A1	-0.025176
MAPKAPK2	0.024915
GNAS	-0.024876
ACTA2	0.024836
PPP1R15A	0.024759
CFL1	-0.024635
NDUFB5	-0.024468
H1FX	0.024428
TAGLN2	-0.024418
GAA	-0.024406
CRY2	0.024361
UQCRQ	-0.024143
LAMP2	-0.024064
TRAF4	0.023970
FKBP1A	-0.023855
GPX3	0.023854
CRTAP	-0.023806
BGN	-0.023715
SMAD1	0.023453
WDR6	-0.023294
DIO2	-0.023236
RPL27A	-0.023221
NREP	-0.023077
ISOC1	-0.022912
APP	-0.022835
GNB2L1	0.022827
AIMP1	-0.022825
SMAD7	0.022822
TXN	-0.022803
TRIM27	0.022658
ECE1	0.022642
NDP	-0.022535
AKR1A1	-0.022468
SPARC	0.022433
PRKCSH	-0.022356
UBE2L3	-0.022021
TKT	-0.021840
FKBP4	0.021838
ZFP36	0.021679
PLET1	0.021641
TFCP2L1	0.021562
GABARAPL1	-0.021483
COPA	-0.021388
MAGED1	-0.021159
DCN	-0.021151
DMPK	-0.021086
OXCT1	-0.021045
KLF3	0.021024
PSMB3	-0.020986
PSMD1	-0.020892
SEC61A1	-0.020837
SLC25A4	-0.020754
HNRNPH1	0.020674
SESN1	-0.020577
ISLR	-0.020557
ID2	-0.020525
KLF4	0.020523
SOX7	0.020473
MAGED2	-0.020470
RNF167	-0.020469
COL1A2	-0.020409
TNPO1	-0.020403
PRR5	0.020399
SOCS2	0.020384
C11orf31	-0.020361
FXYD1	-0.020280
CDKN1A	0.020276
ARHGEF25	-0.020266
KLHL21	0.020249
PPIB	-0.020144
ERGIC3	-0.020140
LMNA	-0.020121
PRKCDBP	-0.020086
PRKACA	-0.019997
LLGL2	0.019916
CD14	-0.019912
HOPX	0.019812
WSB1	0.019712
CDC42EP4	0.019669
PHPT1	-0.019654
SDPR	-0.019609
UQCRC1	-0.019509
CPT1A	-0.019483
FPGS	0.019475
ATOX1	-0.019464
CSDE1	-0.019415
CYR61	0.019384
CTNNB1	0.019360
SPARCL1	0.019229
KRT83	0.019195
GEM	0.019180
SPATS2	-0.018993
VPS37B	0.018990
RAP1GAP	0.018980
CTSD	-0.018973
CNPY2	-0.018925
RPS23	-0.018863
NUDT4	-0.018838
GNAI2	-0.018782
ALAD	0.018754
PERP	0.018567
ITGB1	0.018545
ACO2	-0.018541
SYNPO	0.018392
FASN	0.018350
UQCR11	-0.018340
TRADD	-0.018335
SFR1	-0.018325
DLX5	-0.018287
DSTN	-0.018258
GSK3A	-0.018216
NCOR2	0.018208
BCAT1	0.018123
GSTP1	-0.018079
SMAD6	0.018079
RNF19B	0.018064
PDGFRB	0.018027
GNA13	0.017997
RBBP7	0.017984
CCND3	-0.017977
AKR7A2	-0.017890
CITED2	-0.017884
ECH1	-0.017882
AAMP	-0.017799
NDUFB11	-0.017774
EIF3G	-0.017743
SNRPB	-0.017643
TIMM17B	-0.017599
MDFIC	0.017589
UNC45A	0.017513
PCP4	-0.017502
DPT	-0.017475
KRTCAP2	-0.017434
HPCAL1	0.017434
BAG2	0.017417
GSTO1	-0.017396
EFNB3	0.017320
MRPL30	-0.017314
ST6GALNAC6	0.017282
GADD45B	0.017261
C14orf2	-0.017194
BANF1	-0.017174
PARK7	-0.017102
ANXA5	-0.017040
MBTPS1	-0.017030
WFDC2	-0.017010
AP1S1	-0.017005
RAMP1	-0.016990
SMDT1	-0.016931
MYCL	0.016849
ZNF703	-0.016781
DDX5	0.016778
SNX3	-0.016713
COPS6	-0.016620
HSPH1	0.016601
EIF4A2	-0.016593
PTTG1IP	0.016575
PPP2R1A	-0.016571
EMD	0.016557
TRIO	0.016556
DBNDD2	-0.016500
SLC3A2	-0.016482
USP2	0.016466
NRTN	0.016406
C12orf57	-0.016351
AES	-0.016336
EXTL3	0.016255
IRF8	0.016243
HDLBP	-0.016226
ZFPM1	0.016219
THY1	-0.016191
DBP	-0.016136
STUB1	-0.016119
HES1	0.016102
MAF1	-0.016056
DDX17	0.016032
OSBPL5	0.015920
SRSF6	0.015850
ATP6V1G1	0.015697
RAB20	0.015683
TRIM47	0.015654
MDK	-0.015633
MARK2	0.015609
YWHAG	-0.015600
COA3	-0.015586
RPS12	-0.015569
C6orf89	-0.015545
LITAF	0.015519
CRIP1	-0.015503
SERPINF1	-0.015475
ANAPC11	-0.015449
TOMM7	-0.015358
MYH11	-0.015343
CCT4	-0.015304
SLC6A6	0.015289
UQCR10	-0.015281
ATP6V0D1	-0.015234
FTH1	0.015177
RAMP3	0.015171
RAB9A	-0.015114
DAP	-0.015107
UBL5	-0.015096
C15orf39	0.015063
PLEC	-0.015018
NDUFA5	-0.015007
UQCRHL	-0.014953
NUP50	0.014910
CDR2	0.014873
PLAC8	-0.014854
SLC41A1	0.014821
NT5DC3	0.014805
CYB5A	-0.014771
RAB34	-0.014700
RPS11	0.014674
LTA4H	-0.014665
COX6A1	-0.014613
KLF9	0.014580
UBL3	0.014580
RHOC	0.014573
HSPG2	0.014571
SLC2A3	0.014531
RNASEK	-0.014524
UQCRB	-0.014508
LUM	-0.014480
KLF6	-0.014461
COX7A2	-0.014438
SUN2	-0.014426
TMPRSS2	0.014415
RPL10A	-0.014410
EMP3	-0.014402
PTP4A2	-0.014327
CCNG2	0.014311
NDUFB2	-0.014282
NDUFA2	-0.014277
CLTC	-0.014238
CSF1	0.014223
NOTCH1	0.014134
SEC61B	-0.014096
MDH2	-0.014077
IGF1R	0.014066
RGCC	0.013992
EIF3K	0.013951
POLD2	-0.013937
NFIX	-0.013919
VPS28	-0.013899
MPRIP	0.013884
UGDH	-0.013872
RPS5	0.013867
NDUFS6	-0.013867
EZR	0.013842
CCT7	0.013814
TIMM13	-0.013724
SEC11A	-0.013706
FSCN1	-0.013695
KCNJ8	-0.013675
H2AFZ	0.013670
FKBP11	0.013669
SEPT7	-0.013659
HOXB6	-0.013602
CSRP2	-0.013578
FLII	-0.013556
MLYCD	-0.013545
RNF145	-0.013538
CPE	0.013519
PADI1	0.013506
TINAGL1	0.013505
CA2	-0.013493
ESD	-0.013475
ATPIF1	-0.013457
SDHC	-0.013434
ATP6V0C	-0.013420
NUCB1	-0.013418
TXNL4A	-0.013417
COX17	0.013406
RPS17	0.013366
SLC12A4	0.013301
POSTN	-0.013286
H19	-0.013259
PPDPF	-0.013252
C7orf55	-0.013227
CCT5	-0.013208
HSPA5	0.013202
RNF208	0.013191
PPP1CB	0.013184
CHPF	-0.013133
ZNF644	-0.013099
NDUFB9	-0.013033
DYNC1I1	-0.013024
TXNRD3	-0.013015
LAPTM4B	-0.013007
SEP15	-0.013000
WLS	-0.012976
IMP3	-0.012974
TGFBI	0.012950
WDR83OS	-0.012939
SCD	-0.012923
NUDT16L1	-0.012914
JUP	0.012853
CREB3L1	-0.012848
SHFM1	-0.012702
NDUFA9	-0.012698
ATP6V0E2	-0.012678
MYCN	0.012663