!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Rattus norvegicus
!drug_name	Candesartan
!smiles	CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)O
!drugbank_id	DB00796
!pubchem_cid	2541
!cell_type	NA
!organism	rat
!end_metadata
ND5	0.333500
ND2	0.188996
MAG	-0.150689
RPL31	0.149868
RPL9	0.141296
SDCBP	0.130403
APOD	-0.127673
QDPR	-0.125125
PSAP	-0.122323
RPL26	0.111279
IFITM3	0.108732
B2M	0.105876
CNP	-0.103287
PLP1	-0.101764
RPS11	0.100925
ITM2B	-0.098351
SPARC	0.097830
RPL22	0.096440
RPL37	0.095300
MGP	0.095083
ZFP36L1	0.091253
SIRT2	-0.088691
APOE	-0.088306
ACTB	-0.086517
CA2	-0.085019
RPS4Y1	0.084848
CKB	-0.083056
CD81	-0.081885
RPL39	0.081598
SLC2A1	0.079648
RPS21	0.078292
MRFAP1	-0.077707
RPS16	-0.076671
ACTG1	-0.076483
TUBA1A	-0.076398
SERPINB9	0.074440
RPL11	0.073223
EGR1	0.071351
MAL	-0.070133
TUBA1B	0.069264
CAPZA2	0.068934
RPS27A	0.068856
CST3	-0.067442
TSC22D1	0.067409
CPE	0.067177
FEZ1	-0.066876
RPS6	0.065919
CAMK2B	-0.065906
RPS14	0.065716
STMN4	-0.062284
NFKBIA	0.062136
RPL23	0.061308
CLU	-0.060487
RPL24	0.059793
PTGDS	-0.059588
TNFRSF11B	0.058916
KLF4	0.058679
RPL27	0.058127
APP	-0.058109
MYCBP2	0.057457
RPLP2	0.057284
TJP1	0.057278
RPL19	0.056482
MAP1LC3A	-0.055434
RPL35	0.054873
DNM1	-0.054670
APH1A	-0.053911
NACA	0.053479
RPS9	0.053333
ALPL	0.052521
RPL5	0.052320
BIN1	-0.051805
TMBIM6	-0.051799
TMEM47	0.051691
RPS29	0.051238
RPS12	0.050326
BNIP3L	0.050322
MYL12B	0.050054
ND1	0.049898
GSTP1	-0.049607
MAP3K1	0.049450
CSRP1	-0.048913
ATP1B1	-0.048287
MAOA	0.047921
MOG	-0.047884
KLF9	0.047746
GNB2	-0.047285
RPS8	0.047072
GUCY1B3	0.046976
ATP6V0C	-0.046342
ALDOC	0.046037
PRNP	-0.045412
MYRF	-0.045317
CYTB	0.044982
HSPA8	-0.044275
RAB6A	0.044192
AK3	0.044108
DDX3X	0.043647
MORF4L2	0.043502
CRYAB	-0.043389
MAPK3	-0.043210
LGALS9B	0.043017
TPT1	0.042974
NDRG4	-0.042971
PMEPA1	0.042936
PLAT	0.042876
RPL17	0.042800
CSDE1	0.042728
MAOB	0.042460
CD48	0.042427
SGK1	-0.042274
TMEM59	-0.042168
RPL10	0.041572
ZFAND6	0.041210
SPOCK2	-0.041155
ATP6	0.041036
RPL3	0.040610
PPP2R5A	-0.040331
TAGLN	0.040088
RPS17	0.039938
TALDO1	-0.039496
KANK2	0.039455
EEF2	-0.039032
PTN	0.038926
YWHAB	0.038510
TECR	-0.038191
DMTF1	0.038128
RPL21	0.038050
RPS3	0.038000
RPS25	0.037645
TTC3	0.037610
SLC7A5	-0.037376
MPZL1	0.037189
ARF5	-0.037130
PPAP2B	-0.036960
RPS23	0.036808
RGCC	-0.036575
EEF1G	0.036380
GSTM5	0.036298
BTG2	0.036108
ENO1	0.036065
NOTCH1	0.035896
CPD	-0.035852
MYL12A	0.035801
RPL4	0.035791
DPY19L1	-0.035784
KLK6	-0.035410
RPS7	0.035315
ID2	0.035247
GNG5	0.035177
PLS3	0.035128
RPS13	0.035104
VIM	0.034930
CSPG5	-0.034734
CLTC	0.034726
SLC6A6	-0.034717
GFAP	-0.034685
DUSP1	0.034515
ITGB1	0.034466
PSMD11	0.034285
COPZ1	0.034250
AHNAK	0.034231
GLUD1	0.034018
EDN1	0.033921
GNAS	0.033900
DOCK9	0.033792
ACTA2	0.033714
TSPAN3	0.033448
CFB	0.033367
RPL10A	0.033256
FAIM2	-0.032974
CTSV	0.032658
SNRNP70	-0.032352
HNRNPF	0.032298
ATRN	0.032086
OCLN	0.031870
APBB1	-0.031455
CSRP2	0.031363
TFRC	0.031238
RPL15	0.031136
RPL30	0.031116
FSTL1	0.031093
GRIK5	-0.030990
LDHB	0.030946
BCAN	-0.030906
RTN1	-0.030860
NEK7	0.030664
EIF4A2	0.030596
PSAT1	-0.030228
ATP9B	-0.030169
LEMD2	-0.029652
PCBP4	-0.029494
DLG4	-0.029447
ITGA1	-0.029349
ST6GAL1	0.029312
CAMK2N1	-0.029244
TCEB1	0.028723
ALDOA	-0.028692
RPS27L	0.028635
ATP1B3	0.028477
POMP	0.028357
XDH	0.028081
TCP11L2	0.027696
BTG1	0.027649
CTSS	-0.027561
GNAO1	-0.027557
CNN3	0.027280
GDI2	0.027226
GNA12	-0.027194
FAM160B1	0.027159
TTR	0.027135
ENPP2	-0.027052
COX1	0.026993
PIM3	-0.026877
ATP1A2	0.026785
RPLP0	-0.026461
SEPP1	0.026386
RNF112	-0.026363
STMN1	-0.026231
DEGS2	0.026189
F2R	0.026141
PTPRS	-0.026018
DGKZ	-0.025892
AGRN	0.025763
RPL12	0.025698
RPS15A	0.025678
GRINA	-0.025677
ATP5G2	0.025625
COL1A1	0.025612
GJB1	-0.025423
CDC37	-0.025265
RHOA	-0.025072
CNKSR3	-0.025059
PRKAR1A	-0.024993
CYCS	0.024868
RAB11A	0.024564
DAB2	0.024475
PDHA1	0.024462
NDRG2	-0.024412
MFGE8	0.024364
CTSD	-0.024363
LITAF	-0.024347
GDE1	-0.024300
RPSA	0.024170
HNRNPK	-0.024161
COX7B	0.024105
COL4A5	0.024070
ND4	-0.024060
MATK	-0.024016
MAP3K12	0.023993
FBLN5	0.023831
APLP2	0.023774
PEBP1	-0.023751
ATP1A1	-0.023724
NDUFC1	0.023630
PITPNA	0.023545
ATP1B2	-0.023538
LTBP1	0.023500
AATK	-0.023408
HSD11B1	0.023376
C1QB	-0.023199
YWHAZ	0.023131
NPEPPS	-0.023076
HADHB	-0.023035
TCN2	-0.022762
BECN1	0.022744
AK4	0.022729
SORT1	-0.022712
CAPN2	0.022647
TXNIP	-0.022370
ARC	-0.022109
GRM3	-0.022026
UBQLN1	-0.022005
PTPRR	0.021969
HGS	-0.021892
RAP1B	0.021874
ANXA2	0.021860
CTXN1	0.021817
HNRNPAB	-0.021784
SEC62	0.021614
PLEKHA1	-0.021566
RPL36AL	0.021547
RAPGEF4	0.021445
NCAM1	-0.021418
ATP5H	0.021363
RBFOX2	-0.021344
SQSTM1	-0.021335
CCNG1	0.021319
NAPA	-0.020993
CHURC1	0.020910
LPHN1	-0.020896
NOTCH3	0.020891
GNB2L1	-0.020865
MRPL3	-0.020843
LAMP1	-0.020818
PLLP	-0.020707
CA4	0.020640
C1D	0.020586
TNKS2	0.020561
PFDN2	0.020486
GPD1	-0.020473
PTPN5	-0.020460
JTB	-0.020441
IVNS1ABP	0.020421
HSPB1	-0.020303
NDUFB2	-0.020162
RCN2	0.020144
RALGDS	-0.020099
MBOAT7	-0.020060
MBP	-0.019985
VAMP2	0.019983
PAPSS1	-0.019927
ATP2C1	0.019893
IL33	0.019835
NDUFS7	-0.019770
CX3CL1	-0.019764
GM2A	-0.019679
MIF	-0.019628
FOXQ1	0.019604
SERBP1	-0.019421
FLOT1	-0.019387
GJA1	-0.019383
AQP4	-0.019366
PNRC2	0.019342
CASP1	0.019342
IDI1	0.019341
MATR3	0.019281
TPI1	-0.019216
TKT	-0.019200
TNS3	0.019187
CYFIP2	0.019142
MLLT10	-0.019116
YWHAH	0.019084
FGFR2	-0.019009
SLC27A1	-0.018874
JUN	-0.018860
NME2	0.018840
ANXA5	0.018828
KDR	0.018794
CPSF4	-0.018784
MDFIC	0.018766
RPL27A	0.018644
CFL1	0.018540
DDR1	-0.018401
PPIA	0.018398
CHGB	-0.018390
SPARCL1	-0.018379
PSMA6	0.018344
SRSF11	0.018306
SSR3	0.018289
NIPAL2	0.018224
JAG1	0.018180
CD63	0.018169
GABBR1	-0.018136
CSNK2B	-0.018082
PF4	0.018079
DHX9	0.017999
TRIM8	-0.017942
NDUFB6	0.017932
ATP5C1	0.017805
CNBP	0.017693
COX4I1	-0.017626
NCOA4	0.017620
PHGDH	-0.017617
SUB1	0.017601
PPP1CB	0.017501
PIN1	-0.017426
ACKR3	0.017419
PPP3CA	0.017393
PYGB	-0.017287
VAMP3	0.017278
CD151	-0.017261
MAP3K3	-0.017179
YWHAE	0.017053
ICAM2	0.017045
PKM	-0.017008
NR4A1	0.016902
NR1D2	0.016842
REEP2	-0.016765
SLC6A9	-0.016748
DUSP6	0.016716
NDUFA8	0.016692
UNC5B	-0.016658
UCHL1	-0.016648
FASN	-0.016646
DNAJB9	0.016642
SIRPA	-0.016597
SSH3	-0.016557
DCN	0.016507
SLC3A2	-0.016481
PCYT2	-0.016480
PRKAR1B	0.016460
CRISPLD2	0.016457
BCL2L1	-0.016454
CYC1	-0.016445
PRDX1	0.016438
FOS	0.016428
GPC1	-0.016399
ACLY	0.016392
NELL2	-0.016352
CYP51A1	-0.016345
RRAGA	0.016331
PSMA2	0.016324
BCLAF1	0.016322
GPD2	0.016298
GAPDH	-0.016293
GNAI2	0.016293
SORBS2	0.016228
HSPE1	0.016151
FMO1	0.016150
INPP4A	-0.016080
UBC	0.015972
SCN1B	-0.015886
MAPK8IP1	-0.015829
SOX17	-0.015804
SLC25A4	-0.015797
SLC16A1	0.015788
NCL	-0.015662
MARC2	-0.015630
PHLDB1	-0.015459
KLF6	0.015440
ZFP36	0.015436
RPL18	0.015347
PSME1	0.015344
RPL18A	-0.015342
DDC	-0.015317
SPTBN2	-0.015267
SYT11	-0.015254
MOBP	-0.015193
RPS10	0.015188
IGF1R	0.015125
UBR5	0.015119
GPT	-0.015103
PTK2	0.015101
GAMT	-0.015086
PYGM	0.015038
TSPAN8	0.015008
SH3KBP1	0.014910
HCRT	-0.014895
CCNL1	0.014885
PCNXL3	-0.014883
WFDC1	-0.014874
GOT1	-0.014809
TLN1	-0.014800
NPHP1	0.014779
TRRAP	0.014756
AP2S1	-0.014740
PTTG1IP	0.014718
ATP6V1F	0.014711
RPL14	0.014681
SNCG	0.014611
ERP29	-0.014518
PSMC5	0.014504
PACSIN2	-0.014503
ZNF519	0.014436
HYAL2	-0.014436
NDUFB3	0.014349
TMA7	0.014342
DDN	0.014311
SLC20A2	-0.014292
SLC12A5	-0.014278
HDLBP	-0.014273
EIF4H	-0.014242
GAA	-0.014204
RBPMS	0.014195
PMP22	-0.014186
P4HB	-0.014152
AP2M1	-0.014148
RPS26	0.014068
SNAP25	-0.014011
METAP2	0.014011
ACVRL1	0.013977
ITPR3	0.013946
SGTA	-0.013938
PTP4A1	0.013935
PEX14	-0.013920
NTM	-0.013886
CPT1A	0.013879
COX6A1	0.013856
HSPA13	0.013794
MAGT1	0.013771
SLC25A17	-0.013756
SYNJ2	-0.013747
DNAJA4	-0.013744
PSMB3	0.013735
ABCB1	-0.013714
ID1	0.013677
TRAPPC1	0.013580
CD9	-0.013565
EED	0.013557
SOX10	-0.013541
DNAJB1	-0.013514
TRIM32	-0.013512
UQCRFS1	0.013433
PIP5K1C	0.013412
EPN2	-0.013411
SDHA	-0.013391
NDUFB9	0.013378
SDC4	-0.013338
GNG11	0.013336