!direction	1
!num_genes	340
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!ligand_name	estradiol
!ligand_id	CHEBI:23965
!cell_type	estrogen receptor (ER)-positive MCF7 breast cancer cells
!organism	human
!end_metadata
SLC7A5	0.199484
S100A7	0.143747
TUBB	0.115570
RAN	0.100048
NME1	0.099654
TUBB4B	0.094970
NHP2	0.092743
YBX1	0.091422
HSPA8	0.090847
MRPL3	0.090062
TPD52L1	0.088392
UBE2S	0.086695
PTP4A1	0.085724
DHRS2	0.085036
PTTG1	0.079895
SLC9A3R1	0.076687
CCT2	0.075234
SLIRP	0.074087
EMG1	0.072091
TFF1	0.071776
TUBA1A	0.071310
HSPE1	0.068480
LDHA	0.067174
KARS	0.066719
HSP90AA1	0.066574
TUBA1B	0.065583
IARS	0.065444
ASS1	0.063967
RPS26	0.062635
SIAH2	0.062436
TUBB3	0.062261
SLC3A2	0.062054
MIF	0.061603
EIF4A1	0.060816
NOP58	0.059818
MRPL36	0.058722
TUBA1C	0.058688
KPNA2	0.057967
C1QBP	0.057651
CCT7	0.056891
HSPB1	0.055926
HSP90AB1	0.055377
C20orf24	0.055252
DDX21	0.054390
USMG5	0.053604
RPL22L1	0.051706
NPM1	0.051564
PPIB	0.050759
KRT8	0.050609
BOLA3	0.050007
PHB2	0.048608
TCN1	0.048570
UBE2T	0.048105
PSMB5	0.048033
SNRPF	0.047532
AHSA1	0.047374
STIP1	0.047288
UBE2C	0.047146
CCT6A	0.046868
TUBB6	0.046641
PKIB	0.046209
ND2	0.046186
HIF1A	0.045914
TRIM28	0.045727
SMIM15	0.045707
DYNLT3	0.045505
DNAJA1	0.045086
SERPINA3	0.045040
FDFT1	0.043652
SLC26A2	0.043582
MRPS23	0.043287
HSPB8	0.043201
PRELID1	0.042905
MT2A	0.042431
MRPL15	0.042359
PTGES3	0.042168
FBL	0.042061
ILF2	0.041656
CDC20	0.041647
ANP32B	0.041470
MYEOV2	0.041428
PSMA6	0.041277
DYNLL1	0.041267
PRC1	0.041266
CCNB1	0.040951
TMEM64	0.040550
CCT5	0.040481
CTSD	0.039925
HNRNPAB	0.039658
KRT19	0.039411
KRT18	0.039388
TFRC	0.039124
HMGB1	0.038961
NOP10	0.038619
FKBP4	0.038474
MAPK6	0.038436
TPBG	0.038403
MRFAP1	0.038283
CYC1	0.038261
PLP2	0.038212
POLR2G	0.038091
TSKU	0.037841
EEF1B2	0.037280
CKS1B	0.037137
PPIF	0.036937
PKM	0.036818
TUBB2A	0.035968
NPY1R	0.035826
ARMCX6	0.035698
DDX39A	0.035363
CCT3	0.035093
PSMC3	0.035055
HSPH1	0.034850
TOMM5	0.034743
CDKN3	0.034593
CMC2	0.034445
YWHAG	0.034417
CA12	0.034170
MRPL16	0.034056
GLA	0.032993
UBL3	0.032848
NDUFB9	0.032843
DCTPP1	0.032825
RRM2	0.032703
PRMT1	0.032406
PNPT1	0.032396
STARD10	0.032314
CELSR2	0.032292
FAM96B	0.032165
TMA7	0.032101
ISCU	0.032100
CCT4	0.032043
GLO1	0.032003
PDIA6	0.031882
RUVBL1	0.031820
ABCE1	0.031241
HSPA5	0.031235
JTB	0.031210
SNRPG	0.031133
G6PD	0.031071
FTL	0.030992
IMP4	0.030915
S100A9	0.030804
MAD2L1	0.030763
MREG	0.030728
STUB1	0.030690
RPL24	0.030640
SNRNP25	0.030563
GREB1	0.030556
PBK	0.030480
LYSMD2	0.030146
EIF3D	0.030137
FAU	0.030094
RPL19	0.030093
RPL8	0.030082
XPOT	0.029477
EIF4H	0.029399
CKS2	0.029302
SNHG1	0.029177
PSMD8	0.029155
DNAJB11	0.028768
PHB	0.028578
NAA20	0.028539
RPL17	0.028412
H2AFZ	0.028357
CDK2AP1	0.028356
SYTL5	0.028339
VIMP	0.028205
ATP5G3	0.027870
PEG10	0.027653
ARL6IP1	0.027539
BANF1	0.027519
NCL	0.027445
LAPTM4B	0.027359
CHSY1	0.027263
PAICS	0.026981
RNASEH2A	0.026975
ADRM1	0.026973
RPS14P3	0.026964
PARK7	0.026950
RRS1	0.026936
PRSS23	0.026840
BRIP1	0.026789
ALYREF	0.026545
EGR3	0.026443
ATP1B3	0.026407
DEK	0.026384
MARCKSL1	0.026365
SNRPD3	0.026338
RPS7	0.026307
TFAP2C	0.026252
TCERG1	0.026179
RPF2	0.025912
CCT8	0.025875
CXXC5	0.025838
SEC61G	0.025826
ETF1	0.025794
NAA50	0.025728
MSMO1	0.025711
CIRH1A	0.025691
SNRPD2	0.025674
CEBPB	0.025666
PRMT5	0.025609
H3F3B	0.025540
RPL7L1	0.025505
SRSF2	0.025496
SF3B5	0.025494
UQCRFS1	0.025475
RACGAP1	0.025429
RAB31	0.025323
CANX	0.025084
IGFBP4	0.024853
CACYBP	0.024805
GEMIN5	0.024692
DHCR7	0.024642
SLC38A2	0.024390
NARS	0.024302
NDUFB10	0.024236
NSA2	0.024189
TPX2	0.024109
SRM	0.024107
GGCT	0.024002
ENOPH1	0.023958
RAD51C	0.023870
ATP5B	0.023749
TOB1	0.023704
NUP107	0.023648
NRIP1	0.023646
CYCS	0.023571
GTF3C6	0.023553
PSMB6	0.023551
NDUFS3	0.023547
COX6C	0.023401
CBWD1	0.023394
VDAC1	0.023313
SSR1	0.023284
OSTC	0.023100
EIF5	0.023072
COA4	0.023066
PRR13	0.023065
CNBP	0.023064
TMEM147	0.023021
PSMB3	0.022912
SLC25A5	0.022878
UFD1L	0.022858
PDCD10	0.022836
PRDX4	0.022818
HSP90B1	0.022666
FABP5	0.022636
PRDX6	0.022534
EIF3I	0.022516
AMD1	0.022494
TIMM10	0.022485
DANCR	0.022451
NDUFAF2	0.022380
RCN2	0.022229
PSMD12	0.022159
PA2G4	0.022059
CDK1	0.022028
SSB	0.021973
DRG1	0.021963
SNRPB	0.021910
TMED2	0.021847
EBPL	0.021825
CPNE3	0.021809
C14orf2	0.021722
UBE2M	0.021708
MRPS24	0.021677
SEC13	0.021675
PSMD14	0.021633
PSMG1	0.021626
NOL11	0.021600
PFDN2	0.021536
ODC1	0.021528
PSMC1	0.021440
TPI1	0.021335
RARS	0.021318
DPY30	0.021295
BLVRB	0.021271
LMNB1	0.021264
ATP5G1	0.021223
RNPS1	0.021162
MANF	0.021156
PRR11	0.021141
MRPL14	0.021139
MRPL51	0.021100
CSE1L	0.020962
NDUFA12	0.020931
PSMB7	0.020925
PFN1	0.020885
DKC1	0.020867
KNSTRN	0.020861
GRPEL1	0.020719
RBM24	0.020699
MRPL22	0.020661
SFN	0.020625
ATP5I	0.020574
EIF3E	0.020545
PRPF4	0.020529
MRPL37	0.020518
TXN	0.020467
XRCC5	0.020457
SNHG16	0.020441
C2orf69	0.020382
PNMA1	0.020335
POLE3	0.020322
HSPD1	0.020230
NRAS	0.020057
CALM1	0.020036
ANP32E	0.020018
HSPA9	0.019934
NUP35	0.019921
PPA1	0.019849
TAGLN2	0.019826
CCND1	0.019796
SPCS1	0.019714
POP5	0.019703
CRELD2	0.019676
TRMT10C	0.019630
RPS17	0.019622
EIF2A	0.019588
PSMA7	0.019574
RPSA	0.019485
RET	0.019476
SRSF3	0.019473
PGR	0.019441
MRPL42	0.019407
FAM83D	0.019259
TYMS	0.019231
ABAT	0.019148
CHCHD3	0.019144
NOLC1	0.019125
PSMD2	0.019119
TOP1	0.019119
HSPA4	0.019070
TRMT112	0.019047
BUB1B	0.018988
HAT1	0.018931
MRPL17	0.018838
ZWILCH	0.018778