!direction	1
!num_genes	266
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	Estradiol
!smiles	CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
!drugbank_id	DB00783
!pubchem_cid	5757
!cell_type	NA
!organism	human
!end_metadata
PLAC1	0.120835
IL17RB	0.088158
HCK	0.077517
WISP2	0.076458
EGR3	0.074103
CYP26B1	0.071503
OLFML3	0.070879
ABHD2	0.068982
SGK1	0.063298
MYBL1	0.063173
FRK	0.060407
RET	0.059785
CELSR2	0.059048
PLCL1	0.056506
KIAA0226L	0.056467
NAV2	0.055811
IGFBP4	0.054901
TIPARP	0.054345
CXCL12	0.053918
RAPGEFL1	0.053323
PRSS23	0.053182
PLAT	0.051895
RAB31	0.051378
MAMLD1	0.050572
SYBU	0.048966
BFSP2	0.047867
NPY5R	0.047225
CALCR	0.046653
SLC47A1	0.046571
HOXC5	0.046114
PDLIM3	0.045951
NR5A2	0.045809
FOS	0.045217
ANXA9	0.045182
PGR	0.044194
TPD52L1	0.043723
FOXC1	0.043588
SHH	0.042909
COL21A1	0.042863
ISG20	0.042022
SLC22A5	0.041677
PITPNC1	0.041556
ANKRD11	0.041239
NXPH3	0.040880
NT5DC3	0.040277
SLC22A4	0.040248
PTCD2	0.040204
METTL1	0.039433
SLC19A2	0.038852
SLC29A1	0.037997
ANKRD36B	0.037846
CAV1	0.037501
RAB30	0.037470
PAPSS2	0.037210
DDX10	0.037121
HOMER2	0.035874
PMAIP1	0.035812
SOX5	0.035776
METTL8	0.035412
TMA16	0.035296
OLFML2A	0.034897
LRP8	0.034833
CITED1	0.034791
LRRFIP2	0.034676
STYK1	0.034540
FHL2	0.034516
SLC7A5	0.034344
HEY2	0.034019
FKBP4	0.034001
DIO1	0.033915
HIPK2	0.033862
FKBP5	0.033434
MICB	0.032920
SLC35E2	0.032859
NEAT1	0.032721
DEPTOR	0.032607
NOTCH2NL	0.032476
CHST8	0.032464
LAD1	0.032085
ELF1	0.032068
C3orf52	0.031913
ARSJ	0.031753
FAM216A	0.031677
FJX1	0.031232
RLN2	0.031204
SLC6A6	0.031135
PTGES	0.031091
PTGER3	0.031000
FAM189A2	0.030982
TMEM164	0.030921
PLA2G16	0.030776
NMRK1	0.030508
TIAM1	0.030488
DOCK4	0.030434
UGT2B15	0.030166
HELLS	0.029906
TIPIN	0.029830
CADM1	0.029821
PYCRL	0.029750
NKAIN1	0.029738
C10orf2	0.029723
LINC00341	0.029679
PPP2R2A	0.029658
PPIF	0.029639
SACS	0.029525
DDX21	0.029394
PRLR	0.029374
MAN1A1	0.029267
GREB1	0.028937
P4HA2	0.028922
TSEN2	0.028844
ELOVL2	0.028751
PDZK1	0.028738
P2RY2	0.028644
PCP4	0.028643
SDC2	0.028630
MITF	0.028528
CA12	0.028355
HOXC4	0.028343
HOXC6	0.028099
LIF	0.028033
CUEDC1	0.027896
HSPB8	0.027734
CCNT1	0.027720
HAS2	0.027409
SLC9A3R1	0.027270
MCM10	0.027269
WFS1	0.027267
DHRS11	0.027148
SYNDIG1	0.027111
CAPN15	0.027110
KLF4	0.027011
TDRD1	0.026826
PARD6B	0.026824
ALDOC	0.026759
GPR65	0.026675
NPY1R	0.026638
CAMTA1	0.026636
FAM120C	0.026545
LRIG1	0.026314
UGT8	0.026074
NAA15	0.025995
UGDH	0.025933
AKR1C2	0.025693
KCNK15	0.025550
C14orf132	0.025514
B4GALT2	0.025509
KCNK5	0.025332
ENPP2	0.025285
MIR22HG	0.025255
TNIK	0.025246
ZNF185	0.025222
TRMT2A	0.025209
MYOF	0.025191
WWC1	0.025141
IL6ST	0.025112
URB2	0.025098
PYCR1	0.025088
TFAP2C	0.025045
NBL1	0.025042
PCOLCE2	0.024724
SLC16A6	0.024719
MICAL2	0.024705
PCDHB8	0.024525
NRIP1	0.024525
FAM63A	0.024452
DTL	0.024450
PMCH	0.024417
ZNF124	0.024349
TNFSF10	0.024307
MAN2C1	0.024268
RAB40C	0.024251
C11orf24	0.024230
GNA14	0.024209
RBBP7	0.024180
SLC7A1	0.024166
AEN	0.024114
NOLC1	0.024105
STC2	0.024060
PIM1	0.024032
CYP4F11	0.023997
RPP25	0.023983
RNASEL	0.023944
NOC3L	0.023723
PELI1	0.023674
RASSF2	0.023630
MED24	0.023606
TAF4B	0.023523
JAK2	0.023425
PUS7	0.023365
ABCE1	0.023360
SUSD4	0.023314
TAZ	0.023243
SLC26A2	0.023127
KCTD12	0.023104
PCYT2	0.023103
CDC42EP1	0.023006
RARRES2	0.022996
ESF1	0.022939
SNX24	0.022881
MAP6D1	0.022807
TUBBP5	0.022742
MCM6	0.022468
UGT2B17	0.022460
SMG1	0.022384
RAMP3	0.022308
PTPRE	0.022268
FLNB	0.022238
TMLHE	0.022237
DGCR11	0.022233
MET	0.022199
ARMC6	0.022195
WDR62	0.022115
COA7	0.022112
FICD	0.022112
NADSYN1	0.022105
PDSS1	0.022084
FABP5	0.022064
RBM41	0.022052
AUNIP	0.021949
FAM57A	0.021923
SPIN1	0.021914
MSMB	0.021798
EGR2	0.021792
THAP9-AS1	0.021728
SERPINF1	0.021659
PLAGL1	0.021657
SERPINA1	0.021599
MRTO4	0.021583
MACF1	0.021559
NCS1	0.021517
TMEM51	0.021516
LTBP2	0.021413
ITGA2	0.021338
FAM169A	0.021302
ZNF442	0.021170
ZNF480	0.021114
COL16A1	0.021073
VCAN	0.021012
NAB2	0.020897
CDC6	0.020860
UNC119	0.020813
MBTPS2	0.020806
SLC16A7	0.020732
CTPS1	0.020698
NOL6	0.020684
DHCR7	0.020602
PAQR4	0.020599
MGP	0.020581
SEMA3B	0.020466
CTR9	0.020452
TBX2	0.020451
SERPINA3	0.020371
LINC00342	0.020370
MYC	0.020345
AMD1	0.020288
GPR87	0.020282
IPO4	0.020275
OSBP2	0.020228
PHLDA1	0.020178
OSGIN1	0.020031
DYNLT3	0.020029
TCERG1	0.019896
GNAZ	0.019887
OSTF1	0.019879
ETV6	0.019842