!direction	1
!num_genes	252
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Methotrexate
!smiles	CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
!drugbank_id	DB00563
!pubchem_cid	126941
!cell_type	granulocyte
!organism	human
!end_metadata
PPBP	0.063787
C4BPA	0.061127
EGR1	0.059560
KDM5D	0.051015
PMM2	0.047583
ORM1	0.046628
HIP1	0.044811
FGF13	0.043367
MIR646HG	0.043313
LYZ	0.042881
DSC2	0.042690
ZNF107	0.041334
BTNL3	0.041221
NUCB1	0.041104
HTATSF1P2	0.040425
PF4	0.038998
MAB21L3	0.038685
LGSN	0.037474
CYB5D1	0.035540
CYP26B1	0.035424
DAPK1-IT1	0.035271
AKR1C3	0.034279
SNORA21	0.034043
TRPM6	0.033912
CHPT1	0.033739
CRIPAK	0.033724
SLC26A8	0.033608
RPH3A	0.033560
VCAN	0.033252
NRN1	0.033237
LOC142937	0.033055
MAL	0.032975
LRRC6	0.032789
ZNF431	0.032758
LINC01410	0.032702
LDHB	0.032654
DPYSL2	0.032080
EIF3C	0.031984
OVCH1-AS1	0.031969
JUP	0.031903
GIMAP6	0.031877
PF4V1	0.031376
CHRM3-AS2	0.031210
SNORA28	0.030617
BAMBI	0.030468
TTC26	0.030416
SPCS2	0.030300
CPA3	0.029874
EIF1AY	0.029673
HSP90AB1	0.029619
GIMAP8	0.029496
TNF	0.029198
PCED1B	0.028854
ANKRD22	0.028636
RPS4Y1	0.028571
NRGN	0.028509
HTRA4	0.028450
RPL3	0.028384
HLA-DPA1	0.027935
SIGLEC5	0.027916
TRBV27	0.027899
LTA4H	0.027739
NLRP6	0.027423
PAM	0.027281
SLFN5	0.027147
SLC2A3	0.026878
RPL36A	0.026768
CECR6	0.026559
TRIM6	0.026326
TRIM23	0.026285
SF3A3	0.026145
DDX3Y	0.026105
MFSD9	0.026015
APOL6	0.025945
MAPK14	0.025876
MSL2	0.025784
DAAM2	0.025587
MAFB	0.025519
CHST2	0.025506
DUSP5	0.025483
HIST1H4D	0.025372
SIRPB2	0.025324
NLRC3	0.025229
MYL9	0.024955
SRPK1	0.024849
OLAH	0.024787
BMX	0.024772
SLC7A5P2	0.024702
CD163	0.024512
IL13RA1	0.024476
CCR7	0.024269
DNAJB6	0.024255
KLF10	0.024213
CBWD1	0.024147
BATF2	0.024042
TMEM164	0.024011
TMEM63C	0.023975
ACIN1	0.023950
CCNL1	0.023929
KIF28P	0.023908
LINC00294	0.023762
SCML4	0.023731
CISH	0.023727
GIMAP7	0.023717
MZT2A	0.023704
RPL22	0.023672
RTN1	0.023664
LHFPL2	0.023604
LOC646626	0.023416
ADRB2	0.023382
UVSSA	0.023345
PPP1R15A	0.023263
PIK3CD	0.023151
ND6	0.023082
LMO2	0.023010
ADARB2	0.022881
LOC100506922	0.022827
CCR2	0.022726
TUBB1	0.022475
C8orf60	0.022297
ZNF746	0.022294
MAP2K6	0.022229
EIF4G3	0.022162
BRE-AS1	0.022153
STRN4	0.022123
PRR12	0.022031
SUPT16H	0.022023
BACE2	0.021919
SNORA68	0.021888
HLA-DPB1	0.021780
ASRGL1	0.021742
OR52K3P	0.021565
PTK2B	0.021534
LOC158402	0.021367
SIPA1L2	0.021295
PLK2	0.021211
RAVER1	0.021192
DRAP1	0.021105
MTMR3	0.021050
BICD2	0.021043
ZNF630	0.021022
ALOX12	0.021010
HBD	0.020959
SORD	0.020926
SYNE1	0.020925
TRIB2	0.020639
ALDH1A1	0.020623
PKD1P1	0.020603
PRUNE2	0.020579
MRPS23	0.020551
RPS23	0.020534
KREMEN1	0.020514
CLCN4	0.020457
MEN1	0.020452
CDC42EP3	0.020413
TMEM2	0.020361
RNF135	0.020339
PLEKHO2	0.020307
PKN3	0.020246
GNL3L	0.020244
MAPK13	0.020237
HSPH1	0.020223
LINC00528	0.020205
MMP9	0.020163
SLC25A39	0.020142
TTC7B	0.020090
ZC3HAV1	0.020090
LINC00493	0.019996
CA4	0.019993
CALCOCO1	0.019944
C1orf174	0.019941
SSPN	0.019924
VPS37B	0.019902
IL15	0.019894
TIAM1	0.019867
LOC101929681	0.019858
FNIP1	0.019774
SIK1	0.019762
NFKBIZ	0.019759
CYP4F12	0.019700
MRFAP1L1	0.019673
PTTG2	0.019548
AIM2	0.019528
OTUD3	0.019475
DDIAS	0.019442
SNHG16	0.019408
LOC93622	0.019404
PAGR1	0.019355
TMEM106B	0.019307
FTX	0.019286
CAT	0.019257
PLD6	0.019242
CD7	0.019230
CYP1B1	0.019216
LBH	0.019216
EID3	0.019190
NRROS	0.019181
GOLGA8B	0.019171
LINC00537	0.019074
KIAA0040	0.019062
SORT1	0.019061
PXN	0.019059
KCTD11	0.019012
ASMTL	0.019006
CASP5	0.018906
DDX42	0.018866
CEP63	0.018854
OLIG1	0.018797
TP53	0.018764
TLX1	0.018763
PATL1	0.018732
HHEX	0.018688
PRMT5-AS1	0.018657
LSMEM1	0.018632
LGALS9	0.018625
CR1	0.018609
SLC24A4	0.018600
UBE2J1	0.018536
SUSD1	0.018530
CNNM3	0.018487
USP9Y	0.018457
NPIPB3	0.018453
VCP	0.018432
ATXN2L	0.018417
GALM	0.018396
AOC2	0.018391
FBL	0.018388
POLE3	0.018346
FFAR3	0.018312
SMG1P1	0.018289
SIRT2	0.018273
FHDC1	0.018265
LENG8	0.018220
S100P	0.018162
FAM172A	0.018082
GALNT6	0.018077
MLF2	0.017980
CMTM1	0.017957
CD99	0.017924
TSHZ3	0.017913
FAM118A	0.017892
MID1IP1	0.017836
TBC1D10B	0.017813
HMHA1	0.017801
MED18	0.017757
PLCL1	0.017749
TPST1	0.017742
SF3A2	0.017736
TPK1	0.017708
DNMT1	0.017694
LOC100506585	0.017675
GBP6	0.017579