!direction	1
!num_genes	246
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	Lapatinib
!smiles	CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl
!drugbank_id	DB01259
!pubchem_cid	208908
!cell_type	lapatinib sensitive and lapatinib resistant ErbB2-positive breast cancer cells
!organism	human
!end_metadata
SCGB1D2	0.168370
PAGE2	0.153656
OAZ1	0.148853
SNAR-A1	0.147643
TUBA1B	0.130159
RPS19	0.129382
PAGE2B	0.124248
BMP7	0.120444
SCIN	0.116616
PAGE5	0.101311
COX8A	0.097258
PRDX4	0.096841
ADIRF	0.095108
SUSD2	0.094963
RPS12	0.092790
TFRC	0.089548
XBP1	0.089547
RPS2	0.089513
CPS1	0.084073
CD81	0.082309
SEPT9	0.080714
EIF4A1	0.077291
EEF1G	0.074820
S100A16	0.074635
NDUFS8	0.073883
KRT81	0.073192
RPL35	0.068814
FASN	0.067678
RPL27A	0.067568
RPL31	0.067190
TMED3	0.063326
AP2S1	0.062904
CFL1	0.060988
ATP5L	0.060643
ENO1	0.060490
ACAT1	0.060255
NDUFA8	0.058908
EZR	0.058327
ARL2	0.058235
MIF	0.056647
LPCAT1	0.056551
DHRS2	0.053766
TMEM258	0.053752
NDUFA1	0.053318
ANP32B	0.051273
SDHA	0.050247
RPLP2	0.050123
KRT19	0.049673
SLC9A3R1	0.047464
S100P	0.047243
PSMB1	0.046827
TUBA1C	0.045568
CA12	0.044442
RPL10A	0.043980
RNA28S5	0.043061
ATOX1	0.042878
JMJD8	0.041388
TXN	0.041106
HBE1	0.040808
TIMP2	0.040770
RPS24	0.040750
TMEM256	0.040611
PPT1	0.040459
TKT	0.039743
PGM5	0.039282
LRRC26	0.039157
COX17	0.038540
VPS37C	0.038416
ORC6	0.037650
STT3A	0.037223
COMT	0.037164
SLC7A5	0.036619
MAP1LC3A	0.035683
PDCD6	0.035551
SDF2L1	0.035462
EIF3H	0.035253
HYAL1	0.035136
HDDC2	0.034969
FAU	0.034729
TST	0.034622
S100A6	0.034322
C9orf152	0.034014
TARP	0.033941
RANGAP1	0.033185
RPL27	0.033094
TALDO1	0.032567
MRPL36	0.032428
SCGB2A2	0.032251
SLC25A5	0.032172
RPL13A	0.032139
ATP6AP2	0.032039
EIF2AK1	0.031768
PLOD1	0.031372
CKS2	0.030986
KLF2	0.030903
TMX2	0.030759
RPS3	0.030194
SEC61B	0.030025
ID3	0.029967
RAB9A	0.029490
HIST1H4C	0.029455
APOA1BP	0.029088
CD151	0.029055
MUCL1	0.029041
AARS	0.028945
P4HB	0.028927
POLE3	0.028672
MLPH	0.028510
PCMT1	0.028489
STRA13	0.028157
HSPE1	0.027877
OSBP	0.027847
YIF1A	0.027197
TK1	0.027194
ISG20	0.027109
COX6C	0.027041
DAD1	0.026987
INHBB	0.026843
CITED2	0.026674
NDUFB2	0.026382
GPNMB	0.025995
SOD1	0.025937
EIF1	0.025912
LDHB	0.025714
HADH	0.025634
CRACR2B	0.025437
GTPBP4	0.025328
C1orf64	0.025195
FAM120A	0.024409
HMG20B	0.023920
PTTG1IP	0.023842
ZHX2	0.023838
RPL18A	0.023749
VAMP8	0.023699
EEF2	0.023493
PRDX3	0.023489
KRT8	0.023455
KRTCAP2	0.023440
ETFA	0.023425
LEPREL1	0.023366
TSPAN9	0.023322
DDB1	0.023285
CMC2	0.023102
NPC2	0.022947
GNAS	0.022764
ATP6AP1	0.022716
SAE1	0.022686
MRPL41	0.022469
NDUFB10	0.022464
CD163L1	0.022425
NDUFV1	0.021966
CTSL	0.021904
C16orf58	0.021851
TMED10P1	0.021845
TSPO	0.021771
ODC1	0.021722
CIB1	0.021704
GNS	0.021493
RPL24	0.021374
CKS1B	0.021110
RPL3	0.021084
BAIAP2L2	0.021080
PITX1	0.021073
RPL39L	0.020997
TUBA1A	0.020747
KLF9	0.020698
BRI3	0.020690
SFXN4	0.020574
NOP10	0.020267
CRELD2	0.020158
RPL19	0.020111
DDIT4L	0.020090
ATP5D	0.020073
IMP4	0.020037
ROMO1	0.020036
IGF2R	0.019935
FARSB	0.019792
MT1A	0.019578
EFHD1	0.019561
CAPN1	0.019537
SF3B5	0.019432
GSDMB	0.019416
MANF	0.019327
ATP6V1E1	0.019321
PRDX5	0.019310
HSPA1B	0.019111
PRDX6	0.019081
ANXA2	0.019040
MT2A	0.019000
ARPC5	0.018890
SCYL1	0.018853
PROM2	0.018714
RPLP1	0.018641
KYNU	0.018520
TRMT112	0.018423
LMNA	0.018368
S100A14	0.018298
SIDT2	0.018236
TOB1	0.018162
ZNF622	0.018085
TSPAN13	0.018080
ARHGDIA	0.018037
MPC1	0.018023
UROS	0.017990
DNMT1	0.017902
MRPS12	0.017896
PRDX1	0.017798
TRABD	0.017789
TUBB4B	0.017743
NDUFAF3	0.017389
RHOA	0.017317
KIAA0101	0.017157
UBXN1	0.017146
TBCA	0.017053
PTGES2	0.017042
HSPA1A	0.016980
UBE2M	0.016942
PPP1R14B	0.016876
RRAGA	0.016591
MYO5C	0.016506
CLCN7	0.016497
EVL	0.016432
NUCB1	0.016427
POLE4	0.016421
TSKU	0.016366
SNRPB	0.016284
MORF4L2	0.016248
TMBIM6	0.016171
MRPL21	0.016087
PRPS1	0.016086
SLC7A5P2	0.016061
TMEM109	0.016050
RPN1	0.015998
SUCLG1	0.015976
COX5A	0.015947
EPAS1	0.015833
ESYT2	0.015791
STIP1	0.015719
CUTA	0.015713
NDUFA4	0.015704
STOM	0.015675
PGD	0.015652
XAGE2	0.015598
EIF3D	0.015589
SLC25A10	0.015589
CYP4B1	0.015522