!direction	1
!num_genes	185
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	NICKEL CHLORIDE
!smiles	Cl[Ni]Cl
!pubchem_cid	24385
!cell_type	H4-II-E-C3 LIVER-derived cell line - 140 uM
!organism	rat
!end_metadata
HMOX1	0.079014
P4HA1	0.068637
ERO1L	0.068445
BNIP3	0.067597
SLC2A1	0.064137
ATF3	0.064043
MAFF	0.062477
PDK1	0.060185
MGARP	0.059051
PFKL	0.057971
CCDC181	0.056844
DDIT4	0.055927
ADM	0.051796
LDHA	0.051683
EGLN3	0.050735
TPI1	0.050617
KDM3A	0.046878
ALDOC	0.046373
LMNB2	0.043723
WNT4	0.043528
STBD1	0.042599
KCTD15	0.041663
DDIT3	0.040640
BNIP3L	0.040579
PGK1	0.040503
DNAAF1	0.040382
JMJD6	0.040147
FRS3	0.039956
NDRG1	0.039699
PGM2	0.039615
ALDOA	0.039520
PTGR1	0.039135
BCS1L	0.038520
NDRG2	0.038407
HIGD1A	0.037540
PPP1R3C	0.036294
LOXL2	0.036046
DUSP1	0.035411
AK4	0.035266
AKR1B10	0.035123
PLA2G1B	0.035013
TRIB3	0.035012
NAMPT	0.034812
ERRFI1	0.034475
GCLM	0.033633
JUN	0.033595
ONECUT2	0.033210
MIF	0.032869
APLN	0.032525
RAD52	0.031751
RINT1	0.031606
MEX3B	0.031473
IFRD1	0.031199
KLF5	0.031171
DUSP12	0.031068
P2RY2	0.031020
RLF	0.030753
ZFP36L1	0.030600
ACSS2	0.030576
GCLC	0.030543
MYC	0.029718
PYGL	0.029678
ZNF292	0.029558
RAB40B	0.029239
HPS3	0.029172
ZNF777	0.028969
ANKRD37	0.028877
FGFBP3	0.028815
TRIM27	0.028725
SLC7A11	0.028578
ST7L	0.028427
VEGFA	0.028311
UBE2O	0.028166
SLC35E1	0.028027
AIDA	0.027996
ENO1	0.027492
DHODH	0.027345
PPIP5K1	0.027230
OSGIN1	0.027195
MAP2K1	0.026738
GZF1	0.026587
TRPT1	0.026576
KDM4B	0.026492
MAP3K1	0.026251
C11orf73	0.025920
PCGF5	0.025504
CHSY1	0.025494
TBL2	0.025456
PTGES2	0.025228
PGAM1	0.025153
SLC40A1	0.025058
ZNF330	0.024905
ARL6IP5	0.024791
ZNF654	0.024685
ZNF629	0.024639
ZKSCAN5	0.024286
NAPB	0.024129
GGCT	0.024006
ME1	0.023957
TATDN2	0.023604
GPR146	0.023585
UBE2D1	0.023341
MMP11	0.023186
DTWD1	0.023181
ZSCAN12	0.023168
DSTYK	0.023055
ZBTB10	0.023045
CCDC174	0.022965
LATS1	0.022867
SMTNL2	0.022836
TXNRD1	0.022823
FOXQ1	0.022735
PRKRIR	0.022723
COMT	0.022700
ZMYM2	0.022665
TRIM59	0.022562
ZSCAN21	0.022474
CENPF	0.022474
MACROD1	0.022420
NABP1	0.022347
EMP1	0.022338
RIOK3	0.022205
IGFBP1	0.022158
TRIP10	0.022130
IER3	0.022116
SCD	0.022090
HPS6	0.022049
WHAMM	0.022019
PEX26	0.021880
RNF122	0.021810
NFIL3	0.021723
HYKK	0.021672
FGFR3	0.021566
VPS4A	0.021510
DNAJB9	0.021450
FAM43A	0.021349
TAF1B	0.021286
CA6	0.021215
DUSP8	0.021202
PLOD1	0.021190
OCRL	0.021064
CRY1	0.020808
FBXO30	0.020800
PPP1R13L	0.020785
ARHGEF2	0.020744
LSMEM2	0.020678
TEX10	0.020651
KLF6	0.020622
MKLN1	0.020614
SNAPC1	0.020545
CHD6	0.020524
SQLE	0.020522
UGDH	0.020473
METTL22	0.020406
TRMT12	0.020357
EMILIN1	0.020349
PRELID2	0.020339
ENKD1	0.020276
TACC2	0.020232
H1F0	0.020140
ZNF280B	0.020129
PIR	0.019896
TRAF6	0.019874
CYP51A1	0.019775
FKRP	0.019758
ZDHHC7	0.019624
GYS1	0.019620
CCNL1	0.019613
PPP1R15A	0.019594
RUVBL2	0.019593
NARF	0.019581
ZNHIT6	0.019560
ABCC4	0.019559
ZFAND2A	0.019543
FAM76B	0.019509
TBPL1	0.019502
GABRA5	0.019478
ANXA2	0.019459
RASAL2	0.019416
COQ3	0.019343
ZBTB39	0.019333
DCLRE1A	0.019321
MESDC1	0.019263
TLE3	0.019192
LYST	0.019182