!direction	1
!num_genes	203
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	Methotrexate
!smiles	CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
!drugbank_id	DB00563
!pubchem_cid	126941
!cell_type	HT29
!organism	human
!end_metadata
HAPLN1	0.269591
S100A4	0.226563
TMEM167A	0.216142
DHFR	0.202119
AKR1B10	0.151277
DKK1	0.122934
AKR1C2	0.111473
ZCCHC9	0.101051
AKR1C3	0.098867
UQCRFS1	0.086835
TMSB10	0.083509
SLC25A6	0.083390
FDFT1	0.077253
COX6B1	0.077242
EDIL3	0.075325
AKR1C1	0.072409
GPI	0.071511
CCNG1	0.069397
NDUFS6	0.067548
ECHS1	0.064651
PODXL	0.061728
OAT	0.059777
CAPNS1	0.058271
USMG5	0.055621
OCIAD2	0.053580
GSTO1	0.052881
EEF1A2	0.049745
RPS14P3	0.049549
TSPAN13	0.048796
PGAM1	0.048365
BZW2	0.047323
S100A11	0.044013
ALDOA	0.043923
TMED7	0.043715
NDUFA4	0.043478
DSTN	0.043395
TAF7	0.041365
XRCC4	0.039443
RPL12	0.038808
CHMP2A	0.038177
MSN	0.037657
SPINK1	0.035429
CLPTM1L	0.035107
PSMD2	0.034774
CD55	0.034492
PRDX5	0.033780
C14orf2	0.033594
ID1	0.032727
SSR2	0.032725
MRPL36	0.032511
CMBL	0.032169
CLDN2	0.031828
AP2S1	0.031739
SNRPD2	0.031470
ITM2B	0.031418
CRIP2	0.031295
RGS2	0.031269
RPA3	0.031263
TOMM20	0.031029
SMNDC1	0.030975
WDR54	0.030535
OST4	0.030524
MRPS30	0.030309
HIST1H2BK	0.029972
ATF4	0.029757
EPHX1	0.029555
NDUFV2	0.028844
UFD1L	0.028777
IARS2	0.028530
ANXA5	0.028491
P4HB	0.028414
RPS4X	0.028386
CALB2	0.028143
CRIP1	0.027770
PDIA6	0.027663
FXYD3	0.027663
DHX32	0.027236
CD99	0.027189
CAPN2	0.026979
NDUFB5	0.026699
CKMT2-AS1	0.026514
RPL3	0.026014
RPS23	0.025947
CAV1	0.025876
ETFB	0.025657
NME7	0.025411
SNRPB	0.025198
ADAM9	0.024848
UBA2	0.024693
DAP	0.024636
LASP1	0.024418
FXYD5	0.024418
ANKRD27	0.024382
AGPAT5	0.024297
MRPL3	0.024249
ZDHHC6	0.024178
TYMS	0.024088
PPP1R1B	0.024024
LTA4H	0.023589
ATP1B1	0.023436
MORC4	0.023079
LAPTM4A	0.022917
COTL1	0.022910
S100A16	0.022556
EIF2A	0.022547
HIF1A	0.022495
PAM	0.022350
CKB	0.022317
PHB2	0.022211
OSTC	0.022031
TWSG1	0.021873
ATRAID	0.021782
PTTG1	0.021688
ID2	0.021411
C12orf57	0.021326
EPB41L4A-AS1	0.021319
TCEAL4	0.021066
KPNA2	0.021033
SLK	0.020955
HPCAL1	0.020923
UPF2	0.020670
BCCIP	0.020650
RAB25	0.020550
ZDHHC16	0.020514
GLRX3	0.019939
RPS7	0.019934
UQCR10	0.019909
PLOD2	0.019803
PGM1	0.019690
MRPL33	0.019570
ARL6IP1	0.019432
PSMD11	0.019345
EIF1AX	0.019055
AFG3L2	0.018972
KIAA1191	0.018922
AP2M1	0.018918
TRIM28	0.018865
CAV2	0.018846
RPS2	0.018822
KIAA1598	0.018804
CBWD1	0.018803
SPINT2	0.018693
S100A10	0.018495
SGK223	0.018391
ABLIM1	0.018322
CD59	0.018243
VDAC3	0.018180
SEC61G	0.018143
MXI1	0.018139
ALDH3A2	0.018114
ANXA10	0.018039
ZNF511	0.018036
CYP3A5	0.017861
TUBB2A	0.017719
SYT13	0.017692
YES1	0.017530
ALDH3A1	0.017521
PLEK2	0.017503
MSH3	0.017428
IGFBP7	0.017363
UGDH	0.017219
LINC00493	0.017173
TMEM258	0.017139
PCBP1	0.016930
EIF3A	0.016885
TSPAN1	0.016865
PPP1CB	0.016862
ACADM	0.016860
NEK7	0.016849
TSC22D1	0.016802
EIF2S3	0.016754
COPB1	0.016608
USP14	0.016573
MDH1	0.016459
SFXN3	0.016449
ODC1	0.016421
PSMG1	0.016340
ARMCX6	0.016325
ATP5I	0.016324
GAPDH	0.016232
ANXA2R	0.016230
NHP2	0.016121
AMIGO2	0.016088
RPL23	0.016070
EIF1	0.016068
TPT1	0.016001
MTIF2	0.015983
SH3KBP1	0.015898
NEAT1	0.015895
RPLP0	0.015884
QPCT	0.015867
CCNI	0.015829
TM9SF3	0.015783
TOB1	0.015758
EIF5	0.015745
RTN4	0.015745
PFN2	0.015704
MTHFD2	0.015611
YWHAQ	0.015581
RBBP7	0.015507
SLC25A1	0.015422
HERPUD1	0.015257
COX3	0.015160