!direction	1
!num_genes	271
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Irinotecan
!smiles	CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7
!drugbank_id	DB00762
!pubchem_cid	60838
!cell_type	stomach
!organism	rat
!end_metadata
DDIT4	0.111449
CHAC1	0.104652
RHOB	0.087201
MYL1	0.087169
NR4A1	0.082967
ZFP36	0.082226
GADD45G	0.080366
DUSP1	0.080047
ADAMTS1	0.079614
GEM	0.079524
EGR1	0.077696
ERRFI1	0.072537
GADD45B	0.072357
PIM3	0.071997
PCK1	0.067340
NFKBIA	0.060025
CXCL2	0.059364
RGS2	0.057997
CEBPB	0.056273
JUN	0.053959
SGK1	0.050041
JUNB	0.048960
BTG2	0.047506
KRT15	0.047142
RASD1	0.046421
TSC22D3	0.046162
BHLHE40	0.045420
ARL4A	0.044065
TXNIP	0.044052
FAM43A	0.043589
USP2	0.042719
MCAM	0.041914
RASL11B	0.041749
DUSP6	0.041718
TOB2	0.041472
MB	0.041300
AREG	0.040210
MYLPF	0.039974
PRKACA	0.039774
IER3	0.038902
MKNK2	0.038866
PPP1R15A	0.038646
TMEM252	0.038628
FOXQ1	0.038274
PER1	0.037935
MYC	0.036492
MESDC1	0.036380
SP2	0.035782
GADD45A	0.035540
LMOD1	0.035086
FURIN	0.035003
KRT5	0.034918
HNRNPL	0.034053
HERPUD1	0.033853
FOXP4	0.033550
COL4A2	0.033445
SLC39A1	0.033025
ARC	0.032954
FOS	0.032767
ZYX	0.032412
FMOD	0.032300
ABCG4	0.032205
IER2	0.032004
PDK4	0.031952
SPARC	0.031832
DMPK	0.031325
COTL1	0.031245
RPRML	0.031206
PTPN23	0.031144
HSPA2	0.030961
VBP1	0.030866
IFRD1	0.030687
CEBPD	0.030551
PFKL	0.030377
RNPEPL1	0.030371
C2CD4B	0.030366
DMBT1	0.030202
KCNJ8	0.030187
ATP6V0A1	0.030182
TNNC2	0.030116
HOXA5	0.030047
ATF3	0.029974
KRT1	0.029914
SETD8	0.029867
NFIL3	0.029840
SMIM24	0.029627
KLF4	0.029485
PHLDA1	0.029468
SMTN	0.029395
KRT4	0.029281
FAM83H	0.029241
CDKN1A	0.029014
MINK1	0.028904
KLF2	0.028559
CSRP1	0.028438
SLC38A2	0.028331
UCP2	0.028319
CKM	0.028295
H19	0.028120
NR4A2	0.027902
TRIB3	0.027899
LMCD1	0.027719
SLC4A2	0.027605
MAZ	0.027595
ACTN4	0.027557
FA2H	0.027523
KRTDAP	0.027333
MAPK14	0.027253
PRRC2A	0.027210
CTXN1	0.027201
SLC25A25	0.026989
JPH2	0.026529
MYO1E	0.026447
LDB2	0.026383
ATP4A	0.026289
ADRM1	0.026200
TMEM140	0.026146
HGFAC	0.026050
ATF4	0.026032
GAST	0.026019
CSRNP1	0.025971
FLNA	0.025937
SEC31A	0.025729
CCRN4L	0.025695
IRS2	0.025621
TACC1	0.025510
ENO3	0.025480
ARHGEF25	0.025428
RBM42	0.025364
SERTAD1	0.025345
ATF5	0.025254
KLF10	0.025201
SAP30L	0.025193
PPP1R1B	0.025031
PLEC	0.024998
LTBR	0.024939
GRINA	0.024835
BAK1	0.024776
SLC9A3	0.024715
ACTA2	0.024488
PLIN5	0.024476
RSAD2	0.024450
INHBB	0.024343
HSF1	0.024215
TRIM16	0.024126
MYH8	0.024066
CX3CL1	0.024037
NR0B2	0.024002
HSPB6	0.023976
TMEM109	0.023946
MAFF	0.023919
EGR2	0.023903
KLF11	0.023836
FOXO4	0.023779
ATN1	0.023575
KLF15	0.023566
LPHN1	0.023519
EPN1	0.023403
PCYOX1	0.023314
IGFBP4	0.023203
STC1	0.023193
PRR15L	0.023142
VARS2	0.023014
CLDN5	0.022765
MUC13	0.022729
PA2G4	0.022680
KCNE4	0.022573
CALCOCO1	0.022569
ECE1	0.022541
BARX1	0.022504
TRIM28	0.022461
ZNF703	0.022382
ST5	0.022343
ACTA1	0.022337
CCDC3	0.022317
KCTD15	0.022316
ZBTB7A	0.022297
GNPTAB	0.022230
GGA1	0.022167
MAP2K2	0.021950
UBALD1	0.021910
LSMEM2	0.021822
TRAF4	0.021658
UBQLN4	0.021613
ACSF2	0.021575
ADAMTSL4	0.021574
RAB3A	0.021417
GPR56	0.021403
PHC2	0.021318
HBEGF	0.021275
SCNN1A	0.021242
NPAS2	0.021193
ADM	0.021022
COQ10B	0.021011
LRP10	0.020912
CISH	0.020895
HNRNPUL1	0.020789
CARM1	0.020724
BRI3	0.020689
IRF2BP2	0.020666
POLR2A	0.020631
PTGS2	0.020616
SYVN1	0.020596
PITX1	0.020541
KCNMB1	0.020499
VIM	0.020362
S1PR1	0.020321
UBE3B	0.020270
PENK	0.020261
CCNK	0.020233
DHCR24	0.020193
NOS3	0.020102
RYR3	0.020071
LRRC32	0.019993
CASKIN2	0.019951
ZMIZ2	0.019887
HSPB1	0.019885
HCFC1R1	0.019817
ARHGEF1	0.019783
FBXO34	0.019774
COL4A1	0.019749
MRVI1	0.019661
FGL2	0.019656
MTHFD2	0.019604
ACTN1	0.019582
CYR61	0.019577
NET1	0.019572
TRAK1	0.019553
APBB1	0.019538
FOSB	0.019525
CHERP	0.019449
CKB	0.019354
ABCB9	0.019337
RNF208	0.019309
SUN2	0.019300
DDIT3	0.019282
ATXN2L	0.019264
VASN	0.019223
EVA1C	0.019163
CYP1B1	0.019163
SNAPC2	0.019130
CITED2	0.018962
WSB1	0.018961
GNAI2	0.018957
GALNT6	0.018866
GCLM	0.018831
BCAR1	0.018813
PBXIP1	0.018785
CORO1C	0.018776
ANKRD23	0.018729
FLOT2	0.018695
PCP4	0.018694
GIT1	0.018686
LZTS2	0.018648
CDK16	0.018538
TNXB	0.018509
H1F0	0.018494
STBD1	0.018477
NPEPL1	0.018468
SOD3	0.018424
VAT1	0.018348
TOB1	0.018347
TAF10	0.018340
NNAT	0.018334
ETV3	0.018317
TGFB3	0.018314
AOC3	0.018291
STRA13	0.018280
MFAP4	0.018254
STARD10	0.018240
KANK1	0.018231