!direction	1
!num_genes	219
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Methotrexate
!smiles	CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
!drugbank_id	DB00563
!pubchem_cid	126941
!cell_type	PBMC (peripheral blood mononuclear cells)
!organism	human
!end_metadata
MYL9	0.059666
S100B	0.054451
SNORA28	0.051134
ST6GALNAC1	0.047443
PRKXP1	0.046206
CES1	0.045037
PPP1R14A	0.044479
MYOM2	0.042414
SNORA72	0.042199
PF4V1	0.040901
RHOBTB1	0.038287
IL7	0.038107
KCNN4	0.037619
LOC285835	0.037149
WASF3	0.035881
COL18A1	0.035172
G0S2	0.034967
CXCL8	0.034529
HBQ1	0.033622
LAPTM4B	0.033441
MMRN1	0.032600
CLC	0.032508
MS4A3	0.031149
GPR34	0.030939
ABCC4	0.030763
LOC389834	0.030758
LTBP1	0.030619
XK	0.030428
RNF175	0.030298
SIRPB2	0.029843
SERPINB2	0.029828
FCRL5	0.029335
DDX11	0.029317
LINC00565	0.029194
TEKT4P2	0.028923
NEFL	0.028818
ALOX12	0.028711
GCSAML	0.028583
KRT72	0.028528
PDIA5	0.028200
RPS4Y1	0.028140
CPA3	0.027861
LAMP5	0.027670
KDM5D	0.027461
METTL21B	0.027440
TTC7B	0.027400
CHAC2	0.027320
ITGB3	0.027156
CRISP3	0.026996
ABLIM3	0.026941
BIK	0.026922
PADI4	0.026920
RPS27A	0.026586
LOC642236	0.026530
FAAH	0.026411
S1PR3	0.026190
LOC283914	0.026180
MEST	0.025982
NUCB1	0.025883
EPB42	0.025829
PLA2G4A	0.025786
LGALSL	0.025704
CCR9	0.025496
PAX8-AS1	0.025349
ROBO1	0.025293
NUF2	0.025272
CLEC12B	0.025219
AHSP	0.025122
PASK	0.025012
ADRA2A	0.024907
MXI1	0.024846
TRIM58	0.024795
PDZK1IP1	0.024686
PTX3	0.024581
SIGLEC5	0.024495
MAP7	0.024334
LRRC37A4P	0.024308
TGM5	0.024291
HPSE	0.024240
CEACAM8	0.024055
LYZ	0.024004
LOC730961	0.023902
LINC00852	0.023854
H1F0	0.023844
TNNT1	0.023731
HP	0.023665
SNCA	0.023593
TMEM45A	0.023317
ST20	0.023145
SH3BGRL2	0.023098
LOC285181	0.023069
CAPG	0.023007
GP5	0.022943
NPCDR1	0.022943
NET1	0.022911
TCN1	0.022768
PSRC1	0.022757
TEC	0.022724
SESN3	0.022723
JUNB	0.022696
FZD6	0.022524
BAP1	0.022379
ZDBF2	0.022214
CYB5D1	0.022211
BRE-AS1	0.022130
TCEA3	0.022120
EGF	0.022070
CCDC58	0.022048
FAM124B	0.021978
LOC100288152	0.021830
DEPDC7	0.021782
DSC1	0.021555
OVOS2	0.021528
CSGALNACT1	0.021483
MCAT	0.021338
LOC100506476	0.021222
EPHA4	0.021193
RIC3	0.021152
AURKC	0.021147
F2RL1	0.021126
TSPAN4	0.021122
GPR160	0.020947
TBC1D10B	0.020919
DDX3Y	0.020863
DHRS9	0.020849
PLD6	0.020763
HRASLS	0.020730
PRB1	0.020723
JUN	0.020644
PLEC	0.020615
NID1	0.020597
CDC6	0.020574
FOS	0.020571
SPATC1L	0.020421
GSTM2	0.020224
MS4A2	0.020224
ORMDL3	0.020197
SNHG17	0.020194
TTC8	0.020181
LOC100287497	0.020137
KLF10	0.020009
PRSS21	0.020005
DACT1	0.019986
RPPH1	0.019939
HDGFL1	0.019930
NSG1	0.019924
ERAP2	0.019911
ZNF480	0.019860
CD101	0.019770
ASRGL1	0.019700
CTTN	0.019601
EIF4G1	0.019583
SCRG1	0.019565
PRG4	0.019557
RETN	0.019543
EIF2AK1	0.019503
UAP1L1	0.019502
LY6G5C	0.019438
GRAP	0.019414
SYF2	0.019371
DCLRE1B	0.019357
NCAPG	0.019324
TRBV27	0.019238
MCU	0.019186
PMM2	0.019175
GSTM1	0.019099
C9orf41	0.019073
BPGM	0.019067
IER3	0.018963
LOC100996579	0.018950
USP46	0.018941
GPHN	0.018906
MTMR3	0.018895
UBASH3A	0.018855
RPGRIP1	0.018853
TGFB1I1	0.018783
GIMAP8	0.018769
BCL10	0.018678
RNASE4	0.018666
ACVR2A	0.018502
DSC2	0.018458
MGC70870	0.018420
CNN1	0.018419
JAM3	0.018406
TRIP13	0.018404
CTNNAL1	0.018377
MGLL	0.018362
SLC22A18	0.018324
FNBP1L	0.018268
JADE3	0.018201
SAMD13	0.018184
CKAP4	0.018182
VIM	0.018168
LOC728445	0.018153
RAD54B	0.018070
ZNF711	0.018068
LINC00853	0.018049
FAM118A	0.018045
IMPA2	0.018034
LINC00920	0.018015
PRPF6	0.018006
HTATSF1P2	0.017959
CD93	0.017946
PROS1	0.017943
LAMB2P1	0.017896
SPOCK1	0.017892
ITGA2B	0.017885
LOC101927274	0.017780
PLOD2	0.017779
LINC00563	0.017774
WDR6	0.017772
SPESP1	0.017741
ABHD12	0.017740
FIP1L1	0.017716
CFD	0.017678
IL18	0.017677
PARVB	0.017669
DAPK1	0.017661
LINC01208	0.017630