!direction	1
!num_genes	286
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Methotrexate
!smiles	CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
!drugbank_id	DB00563
!pubchem_cid	126941
!cell_type	PBMC
!organism	human
!end_metadata
MALAT1	0.109207
ANKRD36B	0.091136
HIST1H4C	0.087325
PLEKHA2	0.066124
ANKRD36	0.064428
AGAP4	0.064232
SMC3	0.063176
SMCHD1	0.061740
SLX4IP	0.060803
IQGAP1	0.058208
CCL8	0.055537
ABLIM1	0.053271
OSBPL8	0.050848
LOC100129917	0.050505
KIAA1551	0.050003
NFAT5	0.049395
HELB	0.048976
ATRX	0.048914
SYNC	0.048141
KLF13	0.047093
OTUD4	0.045899
EIF4G1	0.045419
LTN1	0.045354
CXCL10	0.044981
LOC285178	0.043747
CXCL5	0.042791
SLC16A7	0.039953
SLC16A10	0.039639
PTPRC	0.039302
A2M-AS1	0.038487
CHD9	0.037438
SERPING1	0.037392
TTC3	0.036614
SYNJ2BP	0.036521
BOD1L1	0.036173
THRAP3	0.036116
CNTRL	0.036062
SDPR	0.036042
ZNF567	0.035700
CDC42-IT1	0.035379
CXorf38	0.034983
RNF19A	0.034617
KCNJ2	0.034597
KIAA1033	0.034519
ZBED6	0.033896
B2M	0.033313
CXorf21	0.033231
HIST1H3H	0.033014
PRKAR2B	0.032990
CHD4	0.032865
C19orf43	0.032050
IKZF3	0.032046
ATXN7L3B	0.032024
ARHGAP18	0.031776
LOC101927027	0.031750
SLC25A36	0.031568
TRBV27	0.031282
IFIT2	0.031257
HPS5	0.031197
GPAM	0.031068
NRGN	0.030887
RPAP2	0.030767
TSPAN18	0.030726
LY6E	0.030676
NEXN	0.030266
DDX24	0.030143
IFI16	0.030023
CCDC186	0.030013
TUBB1	0.029845
RSAD2	0.029835
ZBED1	0.029630
SPAG9	0.029534
EGR2	0.029475
BEND2	0.029159
FLJ10038	0.029044
ALDH1A1	0.028947
IFIT3	0.028738
PWAR5	0.028637
PCNP	0.028601
SSSCA1-AS1	0.028565
ZNF785	0.028493
SF3B4	0.028440
ZNF641	0.028420
GPATCH8	0.028368
LINC00528	0.028349
ZNF566	0.028309
XAF1	0.027966
SARS	0.027763
SLFN5	0.027567
C2orf88	0.027550
GTF2H3	0.027484
CEP350	0.027448
SNORA21	0.027381
DAPP1	0.027190
P2RY12	0.027177
MYL9	0.027115
PDZK1IP1	0.027017
TEP1	0.026963
CD40LG	0.026944
GNG11	0.026860
RFWD3	0.026817
LOC100134822	0.026758
THAP6	0.026732
AP3D1	0.026713
ZNF136	0.026658
LOC100996286	0.026613
CAPN2	0.026608
C6orf25	0.026538
RASEF	0.026491
EEA1	0.026464
NFATC2IP	0.026387
IFI44L	0.026287
XK	0.026181
EHBP1	0.026167
NGLY1	0.026166
C15orf54	0.026087
MIS18BP1	0.025754
IFI27	0.025501
RPL13P5	0.025458
IFI44	0.025399
HOOK1	0.025329
ZNF655	0.025319
ANKRD13D	0.025228
KCTD12	0.025213
IRF7	0.025185
LNX1	0.024946
ZNF37A	0.024881
IGSF6	0.024851
SNORD8	0.024678
ASAP2	0.024585
ELOVL7	0.024560
PF4	0.024498
OXTR	0.024495
ARID4B	0.024465
P2RY13	0.024465
BBS4	0.024406
FTX	0.024398
CLK4	0.024258
P2RX7	0.024224
LOC100129447	0.024203
LPGAT1	0.024139
MGEA5	0.024061
SAMSN1	0.024043
SON	0.023903
PPP1R10	0.023752
SECISBP2L	0.023752
FLJ13773	0.023684
ANKRD12	0.023653
RGS18	0.023547
ZNF83	0.023522
NKTR	0.023515
CMPK2	0.023458
RNF19B	0.023428
MX1	0.023369
BCL7A	0.023351
NR1D2	0.023320
TTC37	0.023316
SART3	0.023269
TAF15	0.023256
MAP3K7CL	0.023235
CCL2	0.023050
CTDSPL2	0.023018
TNRC6B	0.022969
SEC14L5	0.022904
ESF1	0.022903
LIMS1	0.022840
PF4V1	0.022748
BDP1	0.022746
INO80D	0.022700
MS4A7	0.022667
SOS1-IT1	0.022634
FAM161B	0.022527
HECTD1	0.022504
EZH1	0.022495
LIMA1	0.022348
LOC202181	0.022269
RAD23A	0.022109
PAPD5	0.022078
VGLL4	0.022042
CD3G	0.021995
MOGAT1	0.021981
SIGLEC1	0.021959
TOP1	0.021901
NFKBID	0.021709
PP12708	0.021680
CXCL9	0.021627
DDX11L2	0.021551
ZBTB7A	0.021538
LY6G6F	0.021526
HSH2D	0.021510
CABP5	0.021486
GPS2	0.021431
PRRC2C	0.021332
ZNF254	0.021235
ZFP91	0.021226
SMA4	0.021082
GBP1	0.020954
C19orf33	0.020951
CENPK	0.020890
IFIT1	0.020808
LOC100507281	0.020753
TRIM11	0.020753
SF1	0.020649
KDM5D	0.020600
LTBP1	0.020530
CCNT1	0.020485
RIF1	0.020344
LAP3	0.020303
GFI1B	0.020199
CYCS	0.020193
FLVCR1-AS1	0.020186
SSBP3-AS1	0.020181
KIAA1731	0.020092
MEIS1	0.020055
TRIM38	0.019932
MMD	0.019918
DNAJB14	0.019917
PDGFRL	0.019890
FFAR2	0.019811
FAM169A	0.019775
USP16	0.019678
NBPF10	0.019628
SUZ12P1	0.019603
GLG1	0.019555
STK24	0.019551
IFI6	0.019440
CD79A	0.019360
RBPMS2	0.019298
JAK1	0.019289
TLR7	0.019216
APOBEC3A	0.019198
LGALS9	0.019185
TGS1	0.019089
EHMT1	0.019024
PRKD3	0.019017
HIST2H2BE	0.018994
ANKRD22	0.018957
RPS4Y1	0.018920
BATF2	0.018900
TPSB2	0.018893
EGR1	0.018858
KIAA1147	0.018844
SRGAP2C	0.018809
TYMP	0.018717
CXorf56	0.018717
CCDC88A	0.018662
MORF4L2	0.018657
ID3	0.018651
TRMT2B	0.018638
KLHL24	0.018621
JUND	0.018617
CTSW	0.018500
TMEM158	0.018350
WARS	0.018240
TSPAN4	0.018239
C16orf54	0.018225
MTR	0.018219
UBE2H	0.018182
FAM226B	0.018177
ATP8B1	0.018163
ZEB1	0.018159
LOC100130278	0.018156
RBM5	0.018156
NPHP3	0.018149
RBM27	0.018129
SCFD1	0.018124
RUSC1-AS1	0.018102
CLIP1	0.018066
NAPSB	0.018044
TRIM58	0.018044
FAM118A	0.018042
UCP2	0.017989
TRIM14	0.017984
CLEC4F	0.017964
TPPP3	0.017845
DOCK8	0.017806
XRCC2	0.017787
WDR36	0.017721
IRF5	0.017650
PABPC3	0.017640
KIF21A	0.017628
ALOX12	0.017612
KMT2A	0.017569
GNLY	0.017566
MLH3	0.017531
ADD1	0.017520