!direction	1
!num_genes	267
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	MLN4924
!smiles	C1CC2=CC=CC=C2C1NC3=NC=NC4=C3C=CN4C5CC(C(C5)O)COS(=O)(=O)N
!pubchem_cid	73014187
!cell_type	A375 melanoma cell line - 24 Hours
!organism	human
!end_metadata
GADD45A	0.196918
SNAPC1	0.161245
ZFAS1	0.134422
UAP1	0.117908
SNHG1	0.103094
CYR61	0.091335
CTGF	0.082186
GDF15	0.081119
FTH1	0.080741
C20orf24	0.077859
TXNRD1	0.077382
KRT18	0.074242
FTL	0.074212
NNMT	0.071627
CCNB1IP1	0.070901
DDX21	0.070883
PLK2	0.070363
CAV1	0.068283
SNHG12	0.066052
BLOC1S2	0.065156
HIST1H4C	0.064284
EPB41L4A-AS1	0.062401
PSAT1	0.062142
PDLIM1	0.060877
SNHG17	0.059504
DKK1	0.056875
SLC7A5	0.055943
EBNA1BP2	0.055809
GARS	0.053748
RPS27L	0.053534
NME1	0.052008
NQO1	0.051813
MTHFD2	0.051619
FHL2	0.050917
BOLA3	0.050483
C6orf48	0.050116
SMNDC1	0.048303
SNHG5	0.047590
EIF3D	0.046858
LIMA1	0.045990
TRIAP1	0.045198
CDKN1A	0.044630
RGS2	0.044015
DDX47	0.043973
DDIT4	0.042915
EIF6	0.042535
SNHG15	0.042443
GAS5	0.042301
RPF2	0.042140
ANKRD1	0.041732
ISCU	0.040367
SRXN1	0.040345
PRDX1	0.040315
MDM2	0.040159
TAF1D	0.039864
TFRC	0.039437
BIRC2	0.039273
PPME1	0.039107
AP3S1	0.038944
FBL	0.038888
RRM2	0.038819
DTL	0.038768
IL24	0.037739
GGCT	0.037438
PPIF	0.037245
TRIB3	0.037239
VDAC2	0.037220
EIF1	0.037083
IER5	0.036680
MRPL15	0.036593
RNF114	0.035421
RSRC2	0.034838
SRP19	0.034771
SNRPG	0.034218
SLC3A2	0.034152
RSL24D1	0.034046
RPL41	0.034020
SLIRP	0.033688
MAFF	0.033630
PMAIP1	0.033318
LYRM1	0.033235
DCTPP1	0.033221
PSMA1	0.032894
EMG1	0.032738
EPHA2	0.032703
FAU	0.032498
DDB2	0.032323
FTH1P5	0.032298
ADRM1	0.032203
AMOTL2	0.031965
PFDN2	0.031950
AK3	0.031942
NOP58	0.031746
HIF1A	0.031591
MRPS23	0.031545
RPS5	0.031394
AVPI1	0.031338
HSPA9	0.031219
RND3	0.031006
RPL27	0.030887
GLRX2	0.030776
GBE1	0.030734
EIF3I	0.030630
MRPL49	0.030581
C12orf5	0.030476
FABP5	0.030448
KARS	0.030359
EEF2	0.030176
CKS1B	0.030108
NOC3L	0.029988
NOP56	0.029967
TOMM20	0.029834
AXL	0.029741
PEA15	0.029504
MED10	0.029452
PTTG1IP	0.029368
GTF3A	0.028537
PA2G4	0.028407
EIF2S2	0.028360
AKR1B1	0.028241
PKD1P1	0.028104
NARS	0.027956
RPL26L1	0.027802
MRPL32	0.027634
ASNS	0.027615
CMSS1	0.027593
KRTAP2-3	0.027525
GCLM	0.027483
GNL3	0.027458
GRPEL1	0.027175
HIGD1A	0.027102
POLE3	0.027093
COA6	0.027033
CNBP	0.026900
YRDC	0.026887
DKC1	0.026754
NIFK	0.026703
RRM2B	0.026665
SRSF7	0.026643
YARS	0.026585
FAM216A	0.026533
GRPEL2	0.026351
FDXR	0.026037
ATF3	0.026021
CYCS	0.025951
TNFRSF12A	0.025942
STK17A	0.025909
DEPDC7	0.025771
NSA2	0.025626
DUSP14	0.025483
RRP1B	0.025345
TKT	0.025312
YBX3	0.025274
COX7A2L	0.025020
BCAS2	0.025010
E2F7	0.024674
CCDC86	0.024639
ATAD1	0.024567
CCT3	0.024526
RRN3	0.024497
ATP5L	0.024441
MICALL1	0.024271
DLEU1	0.024120
TMX2	0.023991
TRIM16	0.023921
BLCAP	0.023615
DUSP11	0.023578
PLCXD2	0.023538
IARS	0.023505
TIMM17A	0.023462
CHCHD4	0.023423
WDR3	0.023201
TIMM10	0.023108
CIRH1A	0.022988
PCNA	0.022867
NAA20	0.022748
SDC4	0.022727
TUFT1	0.022727
NPIPA1	0.022656
SNHG6	0.022631
PSMC3	0.022631
RBM39	0.022529
PTPLAD1	0.022481
SNRPD3	0.022422
ATG12	0.022398
PSMA6	0.022359
RRS1	0.022339
MAGEA3	0.022336
TXN	0.022310
GHITM	0.022297
CDC37	0.022129
SDE2	0.022062
GTF2H2	0.021964
DUSP5	0.021852
RPS19	0.021727
SF3A3	0.021666
ADM	0.021450
SNRPA	0.021329
C14orf2	0.021237
BNIP3	0.021217
ETS1	0.021177
RBM18	0.021132
PPM1D	0.021032
KIAA0907	0.020962
DAP3	0.020940
PRDX6	0.020746
MRPS24	0.020742
ESM1	0.020650
BCCIP	0.020594
TRMT11	0.020571
DNAJA2	0.020539
FAS	0.020405
CORO1C	0.020202
JUND	0.020188
SFN	0.020184
SCNM1	0.020088
EIF2S1	0.020078
SERTAD2	0.020035
ODC1	0.019961
ACTG1	0.019960
SLC7A11	0.019923
CMC2	0.019906
PCNP	0.019848
GABARAPL1	0.019765
SET	0.019731
CS	0.019720
ATF4	0.019656
C12orf45	0.019639
ORC6	0.019611
WDR74	0.019599
TAF9	0.019599
CCDC59	0.019578
CEBPB	0.019577
PHB2	0.019469
USMG5	0.019459
MRI1	0.019384
CCDC58	0.019348
SNHG7	0.019259
MAPK6	0.019241
MYL12B	0.019222
NPM3	0.019207
TOMM5	0.019138
GPN3	0.019095
PNO1	0.019018
DRG1	0.019017
ZCCHC8	0.018998
MRPS35	0.018984
EIF4H	0.018948
UBE2M	0.018891
MAGOH	0.018861
CCNG1	0.018785
PSMA4	0.018773
DNAJA3	0.018735
PRDX4	0.018700
JUN	0.018653
DNTTIP2	0.018640
BCAT1	0.018597
SARS	0.018564
GNL2	0.018548
VPS72	0.018500
ITGAE	0.018456
SLC25A32	0.018346
BUD31	0.018320
SHMT2	0.018301
CRIM1	0.018211
NGRN	0.018201
UCA1	0.018181