!direction	1
!num_genes	252
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	MEK inhibitor (MEKi : AZD6244)
!smiles	CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO
!pubchem_cid	10127622
!cell_type	SW480 cancer cells
!organism	human
!end_metadata
MT1F	0.199815
MT2A	0.196370
MT1E	0.184149
MT1X	0.154033
MT1H	0.142930
TUFT1	0.122743
MT1HL1	0.122114
RAP2B	0.082341
KRTAP2-3	0.079902
USP43	0.079622
CYR61	0.075953
F3	0.073651
MYADM	0.071053
SDC4	0.070945
SLC30A1	0.070521
CXCL3	0.066433
TNNC1	0.062321
PIM3	0.061433
GCH1	0.060015
SNAPC1	0.059674
MYL9	0.057789
JUN	0.057261
HEG1	0.057229
KRT80	0.056258
PPME1	0.052405
GADD45A	0.052394
ZXDA	0.051395
MT1G	0.050298
RND3	0.050116
CCRN4L	0.050076
BAMBI	0.049401
TNFAIP2	0.047006
HIST2H2BE	0.046854
ZNF468	0.046447
TMEM2	0.046054
HIST3H2A	0.045822
CST4	0.045639
ZNF260	0.045470
ETS1	0.045199
FAM171A1	0.044320
AJUBA	0.044319
ADM	0.043891
CST1	0.043884
TRIM16	0.043021
NFKBIA	0.042381
TP53INP2	0.042310
NABP1	0.042068
CD24	0.042022
CDKN2B	0.041764
SERTAD2	0.041489
MALAT1	0.040886
RBM12	0.040879
UCP2	0.040703
MIR21	0.040005
TPM1	0.039511
CEBPG	0.039243
CD83	0.038625
SUCO	0.038031
RPL41	0.037971
SFN	0.036262
KLF6	0.036043
ACTG1	0.035694
DKK1	0.035382
MAPK6	0.034986
THBS1	0.034681
MIR503HG	0.033598
FHL2	0.033004
RPL9	0.032758
ICAM1	0.031884
MYL6	0.031725
NR2F1	0.031513
RIN2	0.031390
RGS9	0.031175
GADD45B	0.030948
C6orf62	0.030943
WBP1L	0.030845
MISP	0.030755
SGPL1	0.030606
NOTCH2NL	0.030486
ALDH1B1	0.030468
ZDBF2	0.030453
PLAUR	0.029610
KIAA0226L	0.029598
CRIM1	0.029570
FERMT2	0.029387
SLC5A3	0.029068
OTUD1	0.028865
RPL34	0.028809
VMP1	0.028798
CDV3	0.028189
SH3BGRL2	0.028110
BIRC3	0.027790
EPPK1	0.027496
SRSF6	0.027480
ARRDC3	0.027358
C2orf54	0.027131
LENG8	0.026872
ANAPC11	0.026771
MPP5	0.026751
CITED2	0.026674
MID1	0.026504
ATP1B1	0.026417
FOSL2	0.026403
ODC1	0.026373
STC2	0.025884
ALMS1-IT1	0.025834
CAV1	0.025823
ATF4	0.025664
SELK	0.025542
CHSY1	0.025508
STRADB	0.025325
SLC31A2	0.025315
BIRC2	0.025260
TMEM45A	0.024913
LAMP3	0.024892
EZR	0.024796
MIR22HG	0.024773
EDN2	0.024611
SLC2A3	0.024569
INSIG2	0.024510
SP6	0.024494
UBA52	0.024488
OXTR	0.024136
CSRP1	0.024098
SRF	0.024082
LHFPL2	0.024045
LNX2	0.024025
ZNF680	0.023853
PSTPIP2	0.023847
KLF7	0.023787
KCTD11	0.023759
MYH9	0.023741
ATP13A3	0.023517
JARID2	0.023479
ELF3	0.023420
LOC284454	0.023419
LCOR	0.023414
CTPS1	0.023354
MTHFD2	0.023232
MAP1B	0.023171
MB21D2	0.023028
KRT13	0.023026
ND2	0.022990
RGCC	0.022981
CASC3	0.022954
PARP12	0.022898
CLPTM1L	0.022752
CIRBP	0.022703
RPSA	0.022540
ZNF217	0.022462
TOB1	0.022461
HSPB1	0.022393
ZFPM2	0.022290
RCN2	0.022174
SLC7A1	0.022136
ZNF280C	0.021960
UQCRQ	0.021952
CRISPLD2	0.021897
ULBP2	0.021882
NRIP3	0.021876
FAM13B	0.021809
SS18L1	0.021741
CXCL1	0.021663
C1orf198	0.021659
DYNLT3	0.021626
ZBTB21	0.021543
CASP7	0.021535
TNFRSF21	0.021531
PLEKHA1	0.021421
PLK2	0.021366
PROSER2	0.021348
HOXC6	0.021285
CIPC	0.021243
MAFB	0.021178
RPL7L1	0.021161
MSANTD3	0.021146
POLR2I	0.021140
STEAP2	0.021079
AMMECR1L	0.021017
NPC2	0.020921
UBAP1	0.020788
TNIP1	0.020638
C6orf211	0.020581
ZBTB43	0.020505
CXADR	0.020495
PET117	0.020394
EZH2	0.020320
DDX6	0.020318
RHPN2	0.020277
ZNF562	0.020263
MEST	0.020198
MTM1	0.020182
GTF2E1	0.020176
SNHG1	0.020142
CNN2	0.020142
RAB22A	0.020111
EIF1	0.020097
MAT2A	0.020078
RPL21	0.020019
MIRLET7DHG	0.019908
LRRC47	0.019833
MORC4	0.019828
PPIF	0.019814
MMGT1	0.019810
IL32	0.019764
TRIM68	0.019713
ZNF675	0.019711
LATS2	0.019669
CDH1	0.019660
KRTAP3-1	0.019554
ZNF45	0.019484
PODXL	0.019420
SHFM1	0.019409
TNFRSF12A	0.019318
RPS18	0.019317
KRT23	0.019281
COX2	0.019261
ARL4A	0.019223
BRIP1	0.019215
VCL	0.019132
FAM107B	0.019095
PCSK5	0.019027
RPS7	0.019011
AMD1	0.019006
OPHN1	0.018999
CXCL16	0.018848
NME7	0.018790
POLR3F	0.018755
MPZL2	0.018645
TMEM52B	0.018567
ACTB	0.018535
GTF2A1	0.018493
PSMD2	0.018478
GABPB1	0.018469
CXCL14	0.018425
FUT1	0.018367
COQ10A	0.018354
LOC100507507	0.018305
DDX20	0.018305
LINC01119	0.018304
CDKN1A	0.018302
CAV2	0.018230
CNN3	0.018221
IMPA1	0.018098
IFRD1	0.017918
FAIM	0.017913
CPEB2	0.017889
OXSR1	0.017858
PNMA1	0.017851
MTMR4	0.017848
RNF38	0.017823
MARVELD2	0.017811