!direction	1
!num_genes	322
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Tretinoin
!smiles	CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
!drugbank_id	DB00755
!pubchem_cid	444795
!cell_type	ME180 squamous cell carcinoma cell line - 3 hours 10μM
!organism	human
!end_metadata
CCL20	0.155707
CYP26B1	0.109546
TRIM31	0.096604
IL1B	0.089018
GCNT3	0.085119
CXCL8	0.084182
CYP26A1	0.081133
FOSL1	0.079770
F3	0.079749
LIPG	0.067522
IL36G	0.066834
CDH5	0.065566
DUSP1	0.065336
KIAA0226L	0.064167
RELB	0.058537
GPRC5A	0.057757
MIR614	0.051722
HBEGF	0.049973
FOSB	0.049912
TXNRD1	0.049844
SPOCD1	0.049512
TINAGL1	0.049202
ARHGAP20	0.047535
GLIPR1	0.047279
AGPAT9	0.047076
PTPRH	0.046692
CYSRT1	0.046541
LOC646626	0.046456
SLC20A1	0.046269
IGFL1	0.045996
SDC4	0.045558
ENTPD7	0.045440
TSPAN1	0.044678
FAM83A	0.044443
CRCT1	0.044013
DUSP6	0.043397
CPA4	0.043204
TP53INP2	0.043027
LPIN1	0.042288
TNFAIP3	0.041923
CASP9	0.041515
DRAM1	0.041129
MYPN	0.041069
FAM84B	0.040824
EPHA2	0.040570
IL1F10	0.040489
CLDN23	0.040300
DUSP5	0.039714
PLIN2	0.039448
RGCC	0.039286
NRIP1	0.039192
ITPKC	0.038723
ELF3	0.038317
SAMD4A	0.038303
CYR61	0.038099
GADD45B	0.037695
CEMIP	0.037562
CEACAM1	0.037376
TGFB3	0.037050
LIF	0.036920
TMEM40	0.036735
ST3GAL1	0.036074
KRT23	0.035758
TNFRSF12A	0.035727
WWTR1	0.035629
PISD	0.035526
ARL14	0.035349
SCEL	0.034699
THBS1	0.034366
EGR2	0.034213
SEC14L2	0.034207
BARX2	0.033858
LIPH	0.033822
TBC1D2	0.033764
BIRC3	0.033433
GPR115	0.033358
CTGF	0.033325
ARSI	0.033271
HAS3	0.033255
SGMS2	0.033086
ALOX5AP	0.032858
ACOX2	0.032778
SLC20A2	0.032732
EHD4	0.032694
C3orf52	0.032609
SCNN1G	0.032571
STAT4	0.032001
MYO1E	0.031732
OSBP2	0.031566
GJB4	0.031315
IFIT2	0.031279
TRIB1	0.031068
IER3	0.031041
EDN1	0.031038
SLC19A3	0.031008
TRIM16	0.030816
JPH1	0.030798
ZMYND15	0.030572
TMEM217	0.030336
FERMT2	0.030019
GADD45A	0.030009
IL1A	0.030003
PLAT	0.029890
KCTD6	0.029796
RNF39	0.029792
TMEM2	0.029694
STAMBPL1	0.029614
PFKFB3	0.029015
KRT34	0.028998
ITPRIP	0.028985
MYEOV	0.028928
MAFF	0.028923
NFKB2	0.028737
TAGLN	0.028344
TNFRSF10A	0.028160
SOX9	0.028101
TIAM1	0.027957
SERPINB2	0.027875
LCE3D	0.027704
ZSWIM4	0.027697
NCEH1	0.027618
OAS1	0.027581
ALDH1A3	0.027568
CRISPLD2	0.027532
CHMP1B	0.027432
DOPEY2	0.027427
XPO6	0.027218
KRT80	0.027033
CD55	0.026985
ZFP36	0.026966
ABTB2	0.026677
EPHA4	0.026643
CDR2	0.026617
SDPR	0.026561
EN1	0.026484
CSRNP1	0.026439
LCP1	0.026416
PRSS22	0.026368
CCNDBP1	0.026244
ZYX	0.026027
SLCO5A1	0.025999
FHL1	0.025965
HCAR2	0.025919
C15orf39	0.025893
EVA1A	0.025821
PHLPP1	0.025758
ARHGAP10	0.025668
IL1RL1	0.025589
ABCC3	0.025515
TMEM158	0.025404
NEK6	0.025402
AOX1	0.025385
CDA	0.025369
BCL3	0.025322
IRF1	0.025311
DAW1	0.025251
PAQR9	0.025231
C10orf2	0.025166
CH25H	0.025156
KRT75	0.025023
SLC35F2	0.024965
KRTAP3-1	0.024948
TIPARP	0.024942
SHISA2	0.024898
SCHIP1	0.024888
FAM110C	0.024861
EFHD2	0.024842
SH2D3A	0.024817
CFLAR	0.024780
MFSD12	0.024769
PDLIM5	0.024749
TIMP3	0.024730
INPP1	0.024662
NTRK2	0.024657
ADAM19	0.024594
SMOX	0.024582
LAMC2	0.024578
STC2	0.024570
AEN	0.024518
CCDC120	0.024504
FST	0.024499
CCL2	0.024471
ETV4	0.024402
FAM107B	0.024362
MAP3K9	0.024295
SLFN5	0.024123
PTK2B	0.024022
PHLDA1	0.023995
RP9P	0.023985
ARID3B	0.023979
PHLDA2	0.023968
CSRP1	0.023859
EMP1	0.023825
CPA2	0.023816
PHLDB2	0.023774
KRTAP3-2	0.023599
SPINK6	0.023578
BCL10	0.023546
MAP3K14	0.023536
GRB7	0.023526
APOBEC3B	0.023499
CITED4	0.023487
CLDN4	0.023410
TRIM15	0.023399
DENND3	0.023375
DUSP16	0.023335
KIAA0226	0.023264
SERTAD4-AS1	0.023226
ERO1L	0.023173
TICAM1	0.023034
RASD1	0.022960
MYADM	0.022956
MESDC1	0.022813
MTHFD1L	0.022790
RDH13	0.022790
BCAR3	0.022785
CLCF1	0.022756
RNF19B	0.022698
IFFO1	0.022628
PPTC7	0.022538
SMIM3	0.022509
CAMK2A	0.022500
ADORA2B	0.022470
AIFM2	0.022439
PROSER2	0.022381
GABARAPL1	0.022356
FAM65B	0.022350
IRF2BP2	0.022095
CDC42EP1	0.022079
FLNB	0.022026
TNFAIP2	0.021998
TGFA	0.021982
STK10	0.021939
PSD4	0.021931
ITGA2	0.021792
DLGAP1-AS1	0.021721
PI3	0.021666
STX11	0.021655
SPRED2	0.021575
PRR7	0.021411
NET1	0.021402
BIK	0.021398
CDK7	0.021276
AQP3	0.021267
PTAFR	0.021234
PLAUR	0.021165
SPRED1	0.021132
LDLR	0.021032
TRIO	0.021009
PANX1	0.020992
ETS1	0.020983
CABLES1	0.020901
SOX7	0.020896
ENDOD1	0.020822
C10orf54	0.020798
GUCY1A2	0.020724
UGCG	0.020637
C10orf67	0.020594
CCRN4L	0.020577
USP31	0.020379
TMEM41A	0.020376
SHB	0.020335
LIMA1	0.020327
NPC1	0.020312
CLDN7	0.020308
MAP3K8	0.020234
NCOA7	0.020227
MCL1	0.020194
DOCK5	0.020177
EGLN1	0.020174
TTLL1	0.020167
C11orf24	0.020144
ENC1	0.020100
SLC35C1	0.020099
DCUN1D3	0.020066
SLC16A3	0.020021
GBP1	0.019973
ABCB1	0.019963
ZNF841	0.019933
SPHK1	0.019882
C2orf54	0.019848
SAMD8	0.019832
INO80C	0.019806
HS3ST1	0.019792
IL4R	0.019753
LCE3E	0.019741
PVRL2	0.019719
KLK5	0.019712
GDF15	0.019707
PTGS2	0.019670
RTP4	0.019669
TNS4	0.019603
C1orf52	0.019576
CHPF	0.019568
XDH	0.019560
CAMK2N1	0.019560
GPR37L1	0.019419
TNFSF18	0.019300
JMJD4	0.019279
RAET1L	0.019235
SNX30	0.019160
DAPK2	0.019144
CITED2	0.019092
GFOD1	0.019085
CD83	0.019023
ZNF317	0.019002
EIF2AK3	0.018986
CD70	0.018953
FAM46A	0.018822
ULBP2	0.018818
SPTBN5	0.018788
FJX1	0.018763
LRFN4	0.018720
PPP1R13L	0.018671
CYB5R2	0.018617
JOSD1	0.018568
GPR3	0.018550
ISG20L2	0.018526
RRP12	0.018519
TXK	0.018509
IL13RA2	0.018502
C7orf43	0.018470