!direction	1
!num_genes	132
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Irinotecan
!smiles	CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7
!drugbank_id	DB00762
!pubchem_cid	60838
!cell_type	NA
!organism	rat
!end_metadata
INS	0.121985
HSD3B1	0.067371
GDF15	0.063032
ADAMTS1	0.061895
GEM	0.059326
DDIT4	0.056917
DUSP1	0.056542
ADM	0.054726
IER3	0.045523
RHOB	0.042896
CCRN4L	0.042006
GADD45A	0.041162
BTG2	0.039804
AMY2B	0.039460
CHAC1	0.038372
GADD45G	0.038370
EGR1	0.038059
AQP8	0.037577
PPP1R15A	0.036914
IER2	0.036789
SGK1	0.036603
DUSP6	0.036469
NR4A1	0.035335
NOX1	0.033293
GADD45B	0.032990
HBEGF	0.030369
RASL11B	0.030141
FAM43A	0.029920
KCNE4	0.029691
SPINK4	0.029608
SLC30A1	0.029448
TMIGD1	0.029432
ID2	0.029129
CLDN4	0.029122
JUNB	0.029043
ASB11	0.027200
TUBA4A	0.026677
ZFP36	0.026633
JUN	0.026240
MAT2A	0.026213
AREG	0.026063
ZFAND2A	0.026011
DNAJB1	0.025915
ARL4A	0.025446
FA2H	0.025395
TBC1D2	0.025157
VHL	0.025156
DEPDC7	0.025137
REM2	0.024540
IAPP	0.024370
CEBPD	0.024165
DGKI	0.024112
CSRNP1	0.023923
H1F0	0.023872
BHLHE40	0.023806
RGS2	0.023334
TOB1	0.023332
CHRM5	0.023289
HERPUD1	0.023204
KLF10	0.023094
GPRC5A	0.022484
TSC22D3	0.022424
IFRD1	0.022377
CEBPB	0.022124
CPT1A	0.021957
TUSC5	0.021822
RNASE1	0.021822
CXCL3	0.021746
TULP1	0.021716
SLC35F1	0.021566
BBC3	0.021513
CYP1A1	0.021512
EFNA2	0.021423
GABRG1	0.021259
SLC25A45	0.021158
PIM3	0.021079
PHYHIP	0.021044
WSB1	0.020905
NPTX1	0.020828
IGJ	0.020812
FMO1	0.020723
KLF4	0.020667
HSD17B6	0.020588
NFIL3	0.020536
HS6ST2	0.020514
TRPM8	0.020461
CCR3	0.020383
TSSK2	0.020337
BID	0.020327
CRISP2	0.020035
TTYH2	0.019913
DAPL1	0.019864
VPREB3	0.019790
FGF16	0.019748
ERRFI1	0.019669
ACSM1	0.019632
MYOZ1	0.019607
SLC38A2	0.019563
LTA	0.019526
USP2	0.019367
ADRA1A	0.019330
PANK3	0.019296
SLC25A33	0.019245
NEDD9	0.019145
HIC2	0.019140
PER1	0.019129
VMP1	0.019009
CPB1	0.018977
CTRC	0.018941
TGM1	0.018894
CIDEC	0.018861
NECAB1	0.018730
ZFP36L2	0.018713
TCTEX1D1	0.018701
OVOL1	0.018676
PRLHR	0.018672
CHRNA2	0.018667
OPN1SW	0.018629
TIPARP	0.018562
CD200R1	0.018529
ENDOD1	0.018476
NFKBIA	0.018470
AXIN2	0.018465
CNTN3	0.018428
ODF1	0.018417
KMT2D	0.018394
MAP6D1	0.018359
SLC22A7	0.018328
NHSL1	0.018313
PGF	0.018285
PRR5L	0.018264
CCDC96	0.018146