!direction	1
!num_genes	365
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!drug_name	Estradiol
!smiles	CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
!drugbank_id	DB00783
!pubchem_cid	5757
!cell_type	Thymus (of ovariectomized C57BL/6) - 3 Days
!organism	mouse
!end_metadata
OAZ1	0.144060
RPS12	0.128342
RPS28	0.126726
RPL7A	0.125831
RPL8	0.125643
EEF1A1	0.116226
TUBA1B	0.115316
RPS5	0.110902
RPL10A	0.108006
CTSV	0.107792
RPL6	0.107264
PAIP2	0.106818
RBM3	0.105886
SEPP1	0.103652
RPL19	0.101738
RPS14	0.100978
RPS15	0.098273
LCK	0.098041
PFN1	0.096335
NPC2	0.094681
RPL26	0.094136
RPS3	0.090099
PPIA	0.086927
RPS24	0.086021
RPL38	0.085735
RPS27A	0.085451
RPL35	0.084573
RPL4	0.083294
SNX17	0.081572
ITM2A	0.080221
RPS17	0.079856
CST3	0.078454
THY1	0.077892
PTPRC	0.076773
RPL23	0.071393
RPS4Y1	0.070816
RCSD1	0.070102
RPSA	0.069081
RPS7	0.068668
EEF2	0.068213
TPT1	0.068130
ARHGDIB	0.068074
CFL1	0.066147
GNB2L1	0.065094
ACTB	0.064920
RPS2	0.063425
EIF4H	0.060492
SEPW1	0.059907
DDIT4	0.059788
RPL15	0.059580
RPS10	0.059508
RPL7	0.059451
FAU	0.058580
ACTG1	0.058415
RPS13	0.057625
RPL3	0.057568
PRSS16	0.057526
CYTIP	0.057301
SATB1	0.057261
SH2D1A	0.056980
TXNIP	0.056530
CHCHD2	0.056264
COX4I1	0.055229
AKR1A1	0.055138
LSP1	0.054798
RPS26	0.054696
RPS29	0.054273
PDCD4	0.053722
RPLP2	0.053505
RPL28	0.053298
CD3D	0.053131
LAPTM4A	0.051937
CCL25	0.051129
RPL27A	0.049895
PPIB	0.049561
FKBP5	0.048843
MYB	0.048832
RNF145	0.048051
CD8B	0.047930
CYBA	0.047876
ENDOU	0.047818
RPL11	0.047276
CAPZA2	0.046776
HNRNPK	0.045622
PSMA4	0.045591
CDK9	0.045184
RPL18	0.044886
XRCC6	0.044706
RMND5A	0.044644
MBNL1	0.043698
RPS21	0.043108
MDH2	0.042731
SLC25A3	0.042677
TUBB	0.041646
SARAF	0.041627
FTH1	0.040635
RAG1	0.040613
ARPC5	0.040362
LIMD2	0.040336
RPS23	0.039961
HECTD1	0.039891
BTG2	0.039474
MORF4L2	0.039195
EIF3E	0.038917
CORO1A	0.038711
RPL13A	0.038680
CSDE1	0.038622
NDUFA4	0.038539
CNBP	0.038270
TBATA	0.037978
P4HB	0.037773
VPS4B	0.037063
FAM213B	0.036734
ATP5A1	0.036553
RPS19	0.036438
ZNF22	0.036048
HLA-DQB1	0.035439
APOE	0.035349
TMED2	0.035143
NDUFV2	0.034973
CD3G	0.034964
GNG10	0.034925
S100A8	0.034891
SP3	0.034538
CYB5A	0.034389
TMA7	0.034328
CSTB	0.034128
SPO11	0.033947
RPL21	0.033538
PSMA3	0.033320
TNKS2	0.033280
RPS11	0.033272
SAT1	0.033159
NDUFB11	0.033070
STK17B	0.033014
ETS1	0.032701
GZMA	0.032657
DESI1	0.032542
RPS20	0.032471
CD83	0.032433
SHISA5	0.032349
EIF2S3	0.032340
ITM2B	0.032114
BTG1	0.031913
CD74	0.031911
GDI2	0.031839
RPS18	0.031641
WASF2	0.031152
RPL9	0.031151
GPI	0.031056
MYL12A	0.030864
RAMP1	0.030542
EMC3	0.030479
PYCARD	0.030408
GMFG	0.030236
EEF1G	0.029832
GLCCI1	0.029772
EMG1	0.029707
PCBP2	0.029507
ELK4	0.029447
ARPC4	0.029254
ELF1	0.029159
PTPN18	0.029150
NME2	0.029014
DDX39B	0.028910
PSMB2	0.028764
NACA	0.028762
HEXA	0.028555
PGK1	0.028408
CTSD	0.028201
MPND	0.028175
H2AFV	0.028152
SPINT2	0.028128
RPL13	0.028114
CTSC	0.027734
ISG20	0.027564
POLR2B	0.027561
TYROBP	0.027490
PGLS	0.027172
STMN1	0.027168
GRN	0.027146
C1QA	0.026682
ABRACL	0.026671
RPL14	0.026582
MYL12B	0.026109
COX6B1	0.026086
SUMO2	0.026071
CAPZA1	0.026038
NDUFV3	0.026015
COX7A2L	0.025965
CCR9	0.025852
LARP4B	0.025824
CTSS	0.025755
SERPINB6	0.025723
LY6D	0.025670
SLC25A5	0.025555
KRT18	0.025365
COX6A1	0.025349
STARD7	0.025180
ATP6AP2	0.025087
SIN3B	0.024983
RPL5	0.024706
C14orf166	0.024633
RAP1B	0.024550
VPS26A	0.024494
MAN2A1	0.024453
CLK3	0.024363
DRG1	0.024360
MAN1A1	0.024299
DNAJC8	0.024246
SLC9A3R1	0.023980
DNTT	0.023897
ARHGEF18	0.023807
ARPC2	0.023734
CD3E	0.023647
SNRPD2	0.023541
TP53INP1	0.023533
MPEG1	0.023166
MBTPS1	0.023072
TSC22D3	0.023060
SREBF1	0.022929
ARSI	0.022872
ROMO1	0.022825
ATP6V0C	0.022784
CLPTM1L	0.022730
IFNGR1	0.022695
RAB1A	0.022680
C1QB	0.022679
EMB	0.022642
YPEL3	0.022619
SLC16A1	0.022618
ILK	0.022594
DGKZ	0.022589
ACTR3	0.022469
NFKBIA	0.022461
CCL5	0.022445
ACOT9	0.022425
GIMAP6	0.022416
SEP15	0.022415
SPTSSA	0.022346
HMGN1	0.022333
PDCD6	0.022291
EIF4A2	0.022267
ARHGDIA	0.022267
MCL1	0.022137
RPL10	0.022104
ADA	0.022022
ZFP36L2	0.021987
ANAPC5	0.021957
CD2	0.021884
HMGB2	0.021823
CTSA	0.021774
PARK7	0.021689
SRSF6	0.021685
MORF4L1	0.021657
ZMPSTE24	0.021308
NDUFB10	0.021286
RGS10	0.021047
USO1	0.020989
MFHAS1	0.020963
ATP5G3	0.020876
SUMO1	0.020871
SLC25A4	0.020849
ARF6	0.020821
RHEB	0.020619
PPP1CA	0.020607
HEXB	0.020563
PLTP	0.020543
CD5	0.020484
EIF3F	0.020421
CTSB	0.020402
JTB	0.020201
EIF4G2	0.020175
SAMM50	0.020169
HP1BP3	0.020031
HSPA5	0.019993
INMT	0.019966
ABCG1	0.019961
ATP5D	0.019902
C1QC	0.019830
C6orf62	0.019763
UQCRFS1	0.019709
PRDX1	0.019638
S100A10	0.019594
GOLGA7	0.019568
RPL12	0.019566
MATR3	0.019530
SYTL3	0.019246
TUBA1A	0.019194
API5	0.019191
CNN3	0.019060
COX5A	0.019004
PSMD14	0.018987
UBC	0.018884
TMBIM6	0.018779
FNTA	0.018727
RPL27	0.018675
MAP1LC3B	0.018636
LIFR	0.018603
PSMB9	0.018601
SMC4	0.018563
VDAC2	0.018504
EIF3G	0.018495
MRPL27	0.018488
SIRT7	0.018356
SRP14	0.018322
CTSH	0.018200
CD96	0.018142
NT5C	0.018069
DGKA	0.018061
TAF10	0.018036
CEPT1	0.017999
IER2	0.017941
ATP5J2	0.017919
CCT5	0.017851
TMEM184C	0.017791
HLA-G	0.017743
ZBTB18	0.017589
HSPA14	0.017544
SCARB2	0.017524
CSNK1A1	0.017478
NAGA	0.017441
NDUFA2	0.017419
SUPT16H	0.017359
ANKRD44	0.017308
KIAA0922	0.017255
PHF10	0.017255
SNRNP27	0.017254
SERINC3	0.017192
CFP	0.017182
APOA1BP	0.017151
ATP5F1	0.017109
TMEM147	0.017098
UPF3B	0.017044
MAF1	0.016947
ECI2	0.016924
ATP5C1	0.016921
CRIP3	0.016849
IFI30	0.016787
SPATA13	0.016760
ZDHHC6	0.016747
NDUFA3	0.016740
CLUAP1	0.016633
OXR1	0.016580
CLINT1	0.016559
HDAC3	0.016541
C11orf74	0.016518
C20orf24	0.016514
NDUFA11	0.016485
KIAA1109	0.016471
NDUFA13	0.016452
TMEM160	0.016436
TERF2	0.016426
IL2RG	0.016423
FCGBP	0.016369
TNIP1	0.016291
TDP2	0.016260
CGGBP1	0.016260
ANXA1	0.016183
SMIM14	0.016176
PSMA5	0.016167
CLTC	0.016157
LAMP1	0.016145
ATP6V0E1	0.016084
OAT	0.016029