!direction	1
!num_genes	241
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	Lapatinib
!smiles	CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl
!drugbank_id	DB01259
!pubchem_cid	208908
!cell_type	SKBR3 parental and resistant (SKBR3-R) cell lines
!organism	human
!end_metadata
SCGB1D2	0.203886
PAGE2	0.152923
SCIN	0.143973
PAGE2B	0.125390
RPL27A	0.120290
SNAR-A1	0.117718
PPT1	0.114523
XBP1	0.112636
COX8A	0.107434
BMP7	0.106564
SUSD2	0.104971
TFRC	0.101065
KRT81	0.096954
RPLP2	0.094246
ADIRF	0.090829
CPS1	0.087633
PAGE5	0.087476
S100A4	0.082969
RPL13AP20	0.077732
S100A16	0.077509
DDT	0.075345
KRT19	0.071067
RPL37A	0.068195
PRDX6	0.067438
RPS28	0.065837
NDUFS8	0.065679
ATP5L	0.065206
RPS17	0.064452
TMEM258	0.064240
RPLP1	0.063273
NDUFA1	0.062784
RPL41	0.061176
SEPT9	0.060854
PRDX4	0.060758
ACAT1	0.059024
RPL35	0.058053
EZR	0.057992
COX6C	0.057716
CFL1	0.056400
LPCAT1	0.055409
TRMT112	0.053675
NDUFA4	0.052516
LRRC26	0.052269
SCGB2A2	0.051570
COX5B	0.048633
SDHA	0.047610
MRPL36	0.047022
TMX2	0.046758
HSPE1	0.046362
RPL13A	0.045834
PRDX1	0.045459
PSMB1	0.044856
MRPL41	0.044360
RPS12	0.043841
COX7C	0.043769
PRDX5	0.043513
RPL3	0.043236
SEC61B	0.042911
INHBB	0.042654
CITED2	0.042591
ARPC5	0.042142
ARL2	0.041551
DHRS2	0.040163
CA12	0.040042
SOD1	0.040020
LDHB	0.039726
ATOX1	0.039714
TMEM256	0.039525
CAPN1	0.039345
MAP1LC3A	0.039330
AP2S1	0.039121
C1orf64	0.038402
ATP6AP2	0.038253
CRACR2B	0.037902
TXN	0.037862
FAU	0.036900
TOMM7	0.036140
HBE1	0.035792
COX7A2	0.035309
PTTG1IP	0.035068
RANGAP1	0.034825
TARP	0.034776
EEF1G	0.034318
S100P	0.034205
RPL23	0.033786
NPC2	0.033654
PDCD6	0.033542
PGM5	0.033374
SRP14	0.031721
MUCL1	0.031515
NDUFB10	0.031163
COMT	0.030722
COX17	0.030212
JMJD8	0.030148
HYAL1	0.029624
HDDC2	0.028762
PROM2	0.028660
SAE1	0.028297
STARD10	0.027891
ATP6AP1	0.027841
STOM	0.027397
LILRB3	0.027211
RAB9A	0.027116
ACSL1	0.026986
ROCK2	0.026723
RNF114	0.026676
S100A6	0.026638
SDF2L1	0.026397
RPS29	0.026323
COX4I1	0.026309
TMEM179B	0.026270
RPL23AP64	0.026161
KIAA0101	0.026034
PDCD7	0.026033
NOP10	0.025983
VAMP8	0.025520
TXNDC17	0.025281
SPINT2	0.025239
IL18	0.025203
TST	0.024730
RHOA	0.024659
MIF	0.024546
CYP4B1	0.024525
DDIT4L	0.024474
RPS15	0.024420
SCYL1	0.024089
ITPK1-AS1	0.024044
TMEM14B	0.023951
NDUFV1	0.023939
KRT8	0.023883
NDUFA8	0.023681
P4HB	0.023571
TMED3	0.023384
ANKRD33	0.023365
OSBP	0.023278
SLC7A5	0.022714
CD151	0.022655
C15orf52	0.022567
TMED10P1	0.022500
RPSA	0.022112
CMC2	0.022107
RPL7	0.022014
GTSF1	0.021962
MGST3	0.021729
RPS11	0.021622
SMIM14	0.021587
SLC16A3	0.021559
APOA1BP	0.021484
STT3A	0.021430
KRTCAP2	0.021388
PLOD1	0.021385
UQCRHL	0.021307
PHPT1	0.021255
CLCN7	0.021207
UQCRQ	0.021199
TIMP2	0.021151
ROMO1	0.021146
H19	0.021066
MPC1	0.021065
TSPAN9	0.020954
UQCRFS1	0.020922
CD163L1	0.020766
EFHD1	0.020699
GPNMB	0.020629
GTPBP4	0.020203
TK1	0.020157
TSPAN13	0.020055
UBC	0.020027
SELENBP1	0.019998
TALDO1	0.019793
REXO2	0.019740
B2M	0.019723
SCGB2A1	0.019700
RPL10A	0.019644
TMEM238	0.019543
CCR6	0.019385
C7orf50	0.019289
ERH	0.019220
PRDX3	0.019196
ZHX2	0.019169
ANXA2P1	0.019155
KLF2	0.019035
SPCS2	0.018991
C14orf166	0.018899
GTF2H5	0.018775
C9orf152	0.018557
ATP5D	0.018488
RPL21	0.018468
ETFA	0.018326
RRAGA	0.018253
VPS37C	0.018148
LILRB1	0.018142
SRSF6	0.017902
MSRB2	0.017900
DYNLRB1	0.017694
PGD	0.017573
NME1	0.017542
ATP6V0E2	0.017398
CTSD	0.017391
MRPL18	0.017358
ATP5I	0.017219
CTDSPL	0.017207
YIF1A	0.017122
MORF4L2	0.016949
KYNU	0.016872
PXDN	0.016812
POLE3	0.016723
BRI3	0.016719
RPL39L	0.016674
RPL38	0.016635
UQCC2	0.016626
CRELD2	0.016565
CDAN1	0.016464
MYL12B	0.016429
HK2	0.016404
ANXA2	0.016383
ISG20	0.016344
MTHFD2	0.016297
CRIP2	0.016117
EIF4A1	0.016080
HEXB	0.016074
MRPS12	0.016060
TBCA	0.016019
TSKU	0.016010
PRPS1	0.015966
CIB1	0.015893
WDR13	0.015846
SLC9A3R1	0.015805
MYO5C	0.015764
NDUFB2	0.015762
MANF	0.015681
PNPO	0.015648
LSM4	0.015471
RHOB	0.015449
LMNA	0.015390
BAIAP2L2	0.015310
NDUFAF3	0.015273
EVL	0.015267
DEXI	0.015230
APEH	0.015209
RPS23	0.015172