!direction	1
!num_genes	326
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Irinotecan
!smiles	CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7
!drugbank_id	DB00762
!pubchem_cid	60838
!cell_type	jejunum
!organism	rat
!end_metadata
CCL20	0.129444
CXCL13	0.120142
DDIT4	0.107542
ADAMTS1	0.085927
PLK2	0.079827
GEM	0.078698
MS4A1	0.078603
DUSP6	0.072222
TXNIP	0.070659
REG3G	0.070496
CXCR4	0.068926
P2RY10	0.067882
NFKBIA	0.066405
SGK1	0.065811
ARL4A	0.061539
FKBP5	0.059603
FAIM3	0.059469
PDK4	0.059094
GADD45A	0.058729
ARRDC4	0.057771
EGR1	0.057072
FABP4	0.056968
CIPC	0.056497
CD83	0.055155
RGS1	0.053877
CCRN4L	0.053596
ERRFI1	0.053246
GADD45G	0.053106
GADD45B	0.052802
FABP6	0.051334
SLC38A2	0.050501
TSC22D3	0.049919
FOXQ1	0.049600
N4BP2L1	0.049280
REG3A	0.048397
AREG	0.047937
CFD	0.046352
DDIT3	0.043687
HERPUD1	0.043624
BIRC3	0.043144
RHOB	0.043084
CXCL2	0.043037
RGS2	0.042685
IER3	0.041282
CCNG1	0.041143
CA3	0.041112
WSB1	0.040968
FAM84A	0.040710
PTGS2	0.040252
POU2AF1	0.040017
FAM43A	0.039890
SOWAHC	0.039094
BHLHE40	0.039058
ZNF354A	0.038513
BCL6	0.037740
VCAM1	0.037502
ATF4	0.036583
GREM1	0.036531
IER2	0.036514
CCNL1	0.036281
IDI1	0.036117
THRSP	0.036088
CDO1	0.035919
TGIF1	0.035656
TNC	0.035240
DNAJB1	0.035223
PER1	0.034936
TCP11L2	0.034913
LCP1	0.034861
LTBP1	0.034788
NR0B2	0.034398
GDF15	0.034296
ARL4D	0.034188
LPL	0.033852
IFI16	0.033606
CAV2	0.033539
ADIPOQ	0.032822
RASL11B	0.032799
SPIDR	0.032473
CLU	0.032386
CCL13	0.032066
COL4A5	0.031895
CYP2U1	0.031487
CR2	0.031345
ACKR3	0.031114
CHAC1	0.031113
NET1	0.031081
VHL	0.030812
CEBPD	0.030695
FN1	0.030631
CD79B	0.030562
COL3A1	0.030330
CLEC14A	0.029867
CORO1A	0.029707
IP6K2	0.029511
SATB1	0.029394
IER5L	0.029391
KLF9	0.029069
HEXIM1	0.028988
DUSP2	0.028876
DUSP1	0.028845
CYR61	0.028842
ZFP36L2	0.028814
LYVE1	0.028793
TMEM171	0.028570
F3	0.028538
SLC9A3	0.028367
IRF2BP2	0.028101
POSTN	0.027870
BBC3	0.027846
SPHK1	0.027631
ENPP2	0.027439
JUN	0.027430
DMPK	0.027176
KLF6	0.027175
CDT1	0.027081
FAM118A	0.026985
HSPB1	0.026959
PDP1	0.026927
HSD17B13	0.026898
RTP4	0.026787
ADCK5	0.026758
TSPYL1	0.026463
CHSY1	0.026296
CCDC62	0.026127
CEBPB	0.026033
RGCC	0.025995
TMEM123	0.025983
CD53	0.025969
OGFRL1	0.025935
CYP27A1	0.025897
GBP2	0.025895
BAMBI	0.025818
ZFP36	0.025754
MSMO1	0.025704
NNAT	0.025532
CREM	0.025523
GSTA5	0.025521
APOBEC1	0.025492
VIM	0.025430
IL1R2	0.025403
ZNF395	0.025350
MAP3K8	0.025349
SLC46A3	0.025329
SFXN3	0.025293
SH3BP5	0.025074
EVI2A	0.024983
IRS2	0.024724
TIGD3	0.024635
COLEC12	0.024599
ETS2	0.024585
SLC26A3	0.024438
ARNTL	0.024304
NAPSA	0.024261
KLF10	0.024191
ALAS1	0.024131
FLCN	0.024104
SAT1	0.024083
INSIG1	0.024030
FXYD5	0.023910
MAPK6	0.023862
TUBB2A	0.023775
LOXL1	0.023765
FLNA	0.023706
HSPB6	0.023669
NR4A1	0.023644
IL7R	0.023639
S1PR1	0.023608
RAMP3	0.023518
CISH	0.023468
ZNF367	0.023437
DEGS1	0.023386
TMEM194B	0.023238
PTPRC	0.022821
MAD2L1BP	0.022712
BTG1	0.022704
KLF2	0.022594
PIM3	0.022589
CLDN8	0.022501
ANKRD49	0.022467
SRSF6	0.022385
MKNK2	0.022364
LTB	0.022354
SVEP1	0.022325
B3GALT5	0.022318
MRGBP	0.022312
CYYR1	0.022276
EDN1	0.022232
GLRX	0.022208
TIPARP	0.022193
MAP3K19	0.022175
RBM15	0.022057
S100B	0.022017
IL2RG	0.021993
DUSP14	0.021956
CD69	0.021950
B3GALNT1	0.021885
ABCD3	0.021878
RGS4	0.021796
FZD1	0.021767
COL5A2	0.021760
FDXACB1	0.021748
ALDH1A3	0.021715
SERTAD1	0.021709
DYNLT3	0.021646
MSN	0.021597
CAV1	0.021593
RAC2	0.021514
GPNMB	0.021317
MOXD1	0.021250
HES1	0.021241
EIF4A2	0.021202
LPAR4	0.021159
LALBA	0.021135
DEPDC7	0.021128
ELMOD1	0.021083
TTPAL	0.021034
RASD1	0.020988
MFAP4	0.020983
TBC1D24	0.020966
ASPN	0.020938
IL22RA2	0.020879
YPEL5	0.020853
TRIM35	0.020838
ANXA5	0.020708
CES1	0.020707
TACC1	0.020651
SUN2	0.020630
TMEM252	0.020595
SORBS2	0.020490
UTP3	0.020456
EXO5	0.020412
PTBP2	0.020412
LUM	0.020235
CRYAB	0.020234
PROSER1	0.020188
ECHDC1	0.020161
TMCC3	0.020156
CXCL16	0.020137
UBD	0.020116
ELK4	0.020085
PLAU	0.020060
KLHL24	0.019988
COL4A1	0.019945
SEPT10	0.019917
PIGC	0.019821
DAB2	0.019798
PPP1R15A	0.019756
GGA2	0.019630
WDR6	0.019620
DBR1	0.019605
SLC2A1	0.019552
TRAPPC2	0.019532
SELL	0.019516
CCDC134	0.019502
LAT	0.019466
RMI1	0.019457
SNCG	0.019443
LAPTM5	0.019440
YPEL3	0.019369
PAXBP1	0.019350
DIXDC1	0.019340
INPP1	0.019315
PDZD3	0.019294
GSN	0.019277
CBLL1	0.019243
SIT1	0.019236
CD48	0.019209
DRAM1	0.019104
ELTD1	0.019044
CNOT7	0.018964
CDKN1A	0.018932
HELB	0.018911
AKAP8	0.018875
CCDC68	0.018830
P4HA1	0.018788
UBC	0.018777
GTF3C3	0.018773
ANKRD44	0.018752
PLCG1	0.018742
GBP6	0.018719
HIBCH	0.018700
PRNP	0.018688
ATG12	0.018679
NGRN	0.018676
CC2D1B	0.018649
TPBG	0.018632
PSTPIP1	0.018631
PNN	0.018542
NFATC1	0.018530
SPARCL1	0.018508
FOXA2	0.018485
LIMD2	0.018470
CFL2	0.018470
ZC3H7A	0.018454
VNN1	0.018407
PTN	0.018401
PGAM5	0.018398
IVNS1ABP	0.018394
RABGGTB	0.018387
AMD1	0.018366
FGA	0.018338
RARS	0.018333
PRPF39	0.018328
PTPRCAP	0.018327
TFB2M	0.018267
PIAS3	0.018264
UGGT2	0.018259
KIAA1217	0.018230
PDZRN3	0.018227
ZNF519	0.018219
LRRC58	0.018201
LY6E	0.018196
TFCP2L1	0.018177
INPP5B	0.018175
PCDH20	0.018159
GLRA3	0.018148
TM6SF1	0.018078
HMGCS1	0.018066
NUDT11	0.018060
MED7	0.018043
MMP10	0.018029
ANKRD10	0.018028
FADS1	0.018010
SH2D2A	0.017996
MEOX1	0.017993