!direction	1
!num_genes	294
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	MLN4924
!smiles	C1CC2=CC=CC=C2C1NC3=NC=NC4=C3C=CN4C5CC(C(C5)O)COS(=O)(=O)N
!pubchem_cid	73014187
!cell_type	A375 melanoma cell line - 8 Hours
!organism	human
!end_metadata
TXNRD1	0.175703
HMOX1	0.149744
SRXN1	0.130209
NQO1	0.116121
FTL	0.108260
GCLM	0.103475
HSPA1A	0.100987
SLC7A5	0.090590
SLC7A11	0.090130
GADD45A	0.088060
SNAPC1	0.085097
WNT5A	0.082775
DDX21	0.081371
FTH1	0.080367
NNMT	0.074766
PSAT1	0.073955
NARS	0.073576
PPIF	0.072959
UAP1	0.069423
PTTG1IP	0.068910
CTGF	0.068684
GGCT	0.067627
SNHG1	0.067250
NAA50	0.066024
GMNN	0.065205
LDHA	0.064510
C20orf24	0.063761
MTHFD2	0.062783
CAV1	0.062157
TRIM16	0.060752
CCND1	0.060751
CTSL	0.060124
PDLIM1	0.059810
XPOT	0.059687
GLA	0.059185
GARS	0.058727
RRM2	0.058133
IARS	0.056933
AMOTL2	0.056770
PMAIP1	0.056314
PRDX1	0.055968
ND6	0.054324
DNTTIP2	0.050548
CRY1	0.049126
PLK2	0.048184
ZWINT	0.047847
BNIP3	0.046782
POLE3	0.046495
SLBP	0.046427
ATF4	0.045729
MRPL3	0.045683
RPL41	0.045574
STK17A	0.045432
DTL	0.045321
TNPO1	0.043366
SMAGP	0.043355
CYR61	0.043340
DKC1	0.042829
TFRC	0.042276
DNAJB1	0.041843
SACS	0.039584
SNHG17	0.039368
HOXB2	0.038291
FAT1	0.037638
KRT18	0.036710
IER5	0.036685
SMURF2	0.036561
RCN1	0.036446
RSL24D1	0.036364
MAPK6	0.036249
RAD51AP1	0.035913
ACTB	0.035544
PGAM1	0.035049
ANKRD1	0.034806
GBE1	0.034787
RPL7L1	0.034742
YWHAG	0.034536
MAT2A	0.033881
GLO1	0.033836
EGR1	0.033753
TMEM123	0.033476
KTN1	0.033353
NPIPA1	0.033325
CHCHD4	0.033279
AKR1B1	0.033165
IGFBP4	0.032632
PUS7	0.032590
EIF4A3	0.032479
PKD1P1	0.032425
SMNDC1	0.032326
TXN	0.032238
NDUFB9	0.032238
BCCIP	0.032046
LBR	0.032036
EIF1	0.031948
NEIL3	0.031738
GNL3	0.031329
ZNF367	0.031000
BZW2	0.030913
IGF2BP3	0.030866
FBXO30	0.030635
ADM	0.030566
TOMM20	0.030508
TRIB3	0.030497
DCTPP1	0.030244
CRIM1	0.030244
WBP11	0.029952
PRDX6	0.029881
CTNNAL1	0.029746
LASP1	0.029491
GINS1	0.029407
CCT7	0.029373
TMSB10	0.029160
MTERF3	0.029118
CCDC86	0.028838
GSR	0.028817
IL17RD	0.028787
PCNA	0.028783
EI24	0.028533
STAU1	0.028494
CTPS1	0.028315
ASNS	0.028227
CCT6A	0.028226
ACTG1	0.028153
CKS1B	0.028123
TMEM243	0.028033
EEF1B2	0.028015
PSMA1	0.028000
PTBP1	0.027738
ETF1	0.027592
EXO1	0.027240
ALDOA	0.027186
RAB10	0.027167
PTDSS1	0.027046
PEA15	0.027040
LINC01029	0.027007
EIF2S2	0.026969
PSMD14	0.026961
CCDC59	0.026741
MSN	0.026657
CTSB	0.026451
DIMT1	0.026432
MRPS15	0.026361
SLC3A2	0.026320
SOD1	0.026292
POP7	0.026080
NPTN	0.026065
NAE1	0.026005
NME1	0.025920
FBL	0.025762
WDR43	0.025757
PSMG2	0.025754
ALAS1	0.025719
HSPA9	0.025638
EPHA2	0.025548
FERMT1	0.025309
LAMC1	0.025242
DEGS1	0.025213
ZFAS1	0.025045
LARP1	0.024949
RRP1B	0.024838
MARS	0.024667
FEN1	0.024547
NCL	0.024308
PSMD12	0.024291
KARS	0.024201
ASAP1	0.024166
KPNB1	0.024112
CMSS1	0.024101
ATP1B3	0.024092
TIMM10	0.024005
RPS12	0.023961
UHRF1	0.023926
TOMM5	0.023917
ANP32B	0.023858
ARCN1	0.023828
RPS15	0.023811
HK2	0.023810
DNAJA2	0.023809
TRIM28	0.023619
CS	0.023608
EEF2	0.023584
MRPL49	0.023571
SRP19	0.023460
SNHG7	0.023304
YARS	0.023258
PHB2	0.023159
SETD1B	0.023136
PITPNB	0.023102
MAFF	0.023065
PHGDH	0.022782
ZFAND2A	0.022761
STARD7	0.022757
SF3A3	0.022754
EIF2A	0.022736
DLEU1	0.022707
USP1	0.022688
CTH	0.022599
EIF3J	0.022581
GSTP1	0.022538
DHX15	0.022533
KIAA0020	0.022494
SLC38A2	0.022410
E2F6	0.022384
CIRH1A	0.022317
MSH6	0.022265
BCAT1	0.022260
ANKRD27	0.022209
GRPEL2	0.021925
CDC6	0.021844
TM4SF1	0.021759
GEMIN5	0.021749
VDAC3	0.021644
TCERG1	0.021638
BIRC2	0.021618
NOLC1	0.021594
RPS29	0.021534
SLC38A1	0.021518
ATP6	0.021460
HNRNPAB	0.021366
COX3	0.021286
ISCU	0.021272
MXI1	0.021268
CDV3	0.021266
TUBB2A	0.021199
NOP56	0.021158
NDRG1	0.021129
ESM1	0.021055
LPCAT1	0.021010
RACGAP1	0.020943
CSDE1	0.020904
CAPN2	0.020904
RPL8	0.020761
BUB1B	0.020754
DARS	0.020654
HIF1A	0.020627
SACM1L	0.020564
C12orf29	0.020563
MIR21	0.020508
RAN	0.020348
PRKRIR	0.020311
LOC399491	0.020267
TMX2	0.020232
AP3S1	0.020154
PSMD11	0.020136
SET	0.020098
AFG3L2	0.020087
RRS1	0.020085
ENO1	0.019929
TAF1D	0.019863
PNPT1	0.019836
GPI	0.019813
UTP18	0.019801
POLR3K	0.019798
FABP5	0.019759
SNRPE	0.019758
RPS11	0.019750
VDAC2	0.019748
RCC2	0.019661
RPS2	0.019657
MDM2	0.019513
UNG	0.019443
ME1	0.019384
TIPIN	0.019342
EIF4H	0.019256
IFRD2	0.019113
PA2G4	0.019113
DUSP14	0.019110
NUSAP1	0.019068
PSMA6	0.019054
POPDC3	0.019008
TES	0.019002
RBBP8	0.018897
PTPLAD1	0.018880
EPS8	0.018788
LRP8	0.018773
MRPS24	0.018701
TOP1	0.018656
COA6	0.018630
EPDR1	0.018593
TYMS	0.018591
SNHG12	0.018573
UBE2G1	0.018530
DNAJB4	0.018408
ILF2	0.018392
TARS	0.018378
NSUN2	0.018265
DNAJC2	0.018170
RPL23A	0.018147
NDUFA12	0.018141
KRTAP2-3	0.018120
PABPC4	0.018106
MT2A	0.018080
CFAP20	0.017994