!direction	1
!num_genes	220
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Heroin
!smiles	CC(=O)OC1C=CC2C3CC4=C5C2(C1OC5=C(C=C4)OC(=O)C)CCN3C
!drugbank_id	DB01452
!pubchem_cid	5462328
!cell_type	striatum, day 24 withdrawal
!organism	mouse
!end_metadata
PMCH	0.226412
FOS	0.083264
ND6	0.075417
EGR2	0.073788
OXT	0.067501
FIG4	0.062967
HCRT	0.059211
CARTPT	0.058255
C1QL2	0.054601
SLC12A5	0.054024
CCT5	0.053769
SPINK8	0.052975
GAL	0.050536
ARC	0.046455
ECEL1	0.046002
TSR3	0.042572
SUGT1	0.038099
GLUL	0.037919
TSPYL4	0.037753
JUNB	0.037226
VPS4B	0.034852
ZIC1	0.034737
SLC25A4	0.034231
USMG5	0.034114
DLK1	0.033831
SPON1	0.032540
NDUFB4	0.031920
EGR4	0.031908
IGSF1	0.030589
AGT	0.029499
H3F3C	0.029234
SLC5A7	0.029008
ISL1	0.028795
TMIE	0.028678
SLC30A4	0.028106
PDYN	0.028037
DGKK	0.027888
PCP4	0.027625
MICU3	0.027462
CDC123	0.027443
SPARC	0.027416
NGB	0.027083
C16orf80	0.026810
SOX2	0.026745
PHYHIPL	0.026595
GCLC	0.026496
ARHGAP33	0.026267
EAPP	0.026214
GPX3	0.026149
ITIH3	0.025782
SERPINA9	0.024895
KCNE2	0.024855
MXI1	0.024642
IDI1	0.024227
NDUFB5	0.023949
TSPAN3	0.023733
ZCCHC12	0.023514
HES5	0.023134
LIN7C	0.022867
STK32B	0.022834
SWI5	0.022642
IMPA1	0.022553
FFAR3	0.022518
DNAJB4	0.022442
SLC3A2	0.021521
LRRC4C	0.021000
RNF115	0.020864
TXNRD1	0.020813
FREM3	0.020676
GNB2L1	0.020595
PTGDS	0.020271
PAN3	0.020186
PMPCB	0.020071
FIBCD1	0.019954
ERP44	0.019653
TNFRSF25	0.019522
ESYT3	0.019425
SYTL4	0.019288
CTSS	0.018853
LGALS3BP	0.018745
ARF4	0.018733
ANO2	0.018522
PAICS	0.018313
REC8	0.018297
PRR7	0.018289
MRPL39	0.018289
COX7B	0.018095
FDX1L	0.017919
NDUFC2	0.017797
GATM	0.017701
NLGN1	0.017632
RGS14	0.017607
PRPF38B	0.017515
RXFP3	0.017454
ISG15	0.017377
LZTS3	0.017346
GPR6	0.017308
IDO1	0.017294
PAM	0.017274
TBC1D8	0.017251
RWDD2B	0.017195
CLTA	0.017088
ZFAND1	0.016913
ZNF687	0.016792
SLC18A3	0.016572
GABRA1	0.016533
DUSP1	0.016517
YWHAZ	0.016389
IL22RA1	0.016133
DIO2	0.016014
HPD	0.015695
ACTB	0.015622
CLIC6	0.015605
ARHGAP5	0.015586
SARNP	0.015580
KCNA5	0.015543
CRH	0.015480
ASB11	0.015459
INMT	0.015457
PLIN2	0.015381
GPR149	0.015355
ACTR6	0.015352
CYCS	0.015348
UBE2Z	0.015313
CCL5	0.015311
FZD2	0.015304
PER2	0.015253
OTX2	0.015238
TBL3	0.015237
CPSF3	0.015224
DDX3X	0.015170
HSP90AA1	0.015127
HNRNPU	0.015096
DIO3	0.015092
MRGPRG	0.015086
DEF6	0.015068
DUSP14	0.015060
USP10	0.015046
RAD21	0.015032
PRLR	0.015011
OCM	0.014950
PECR	0.014945
ISCA2	0.014868
TRPC7	0.014829
ARL4D	0.014818
LRP1	0.014731
SNCG	0.014665
RARB	0.014664
NECAB1	0.014661
SH3D19	0.014642
TRAF7	0.014545
PCNA	0.014532
UTP15	0.014528
RAB39B	0.014517
PENK	0.014442
TSPAN13	0.014392
SLC37A4	0.014355
SYT17	0.014281
STEAP1	0.014237
LANCL3	0.014193
RESP18	0.014190
DRD1	0.014160
IER5L	0.014140
DND1	0.014118
IRS2	0.014068
SLC24A1	0.014065
OTOF	0.014061
SCX	0.014053
PIM2	0.013970
SPP1	0.013935
NDUFAF5	0.013897
TBC1D21	0.013879
GRP	0.013868
KTI12	0.013855
HEXB	0.013822
SLC25A25	0.013758
TRHR	0.013752
ACTR8	0.013620
RER1	0.013603
TOP2B	0.013559
NONO	0.013515
HIST1H2AB	0.013511
RGS9	0.013492
SLC10A4	0.013490
JMJD1C	0.013447
LHX8	0.013440
C2	0.013425
MAGEE2	0.013339
HAP1	0.013241
TBPL1	0.013229
PGAM1	0.013220
SLC22A3	0.013210
PER1	0.013174
CIART	0.013153
EIF5A2	0.013130
SRP72	0.013112
ALCAM	0.013092
NRARP	0.013026
PSMA6	0.013021
RMI1	0.013003
FAM196B	0.012978
DPF2	0.012946
THRA	0.012922
SMU1	0.012896
CLEC3B	0.012884
HNRNPA2B1	0.012863
CDC42SE2	0.012825
AMD1	0.012807
PDAP1	0.012806
HOXA6	0.012762
NGFR	0.012716
KLHL2	0.012628
SH3GLB1	0.012621
PSCA	0.012579
MRPL13	0.012537
FOSB	0.012512
UCP1	0.012491
CAMSAP3	0.012478
EVPL	0.012459
PCNP	0.012437