!direction	1
!num_genes	309
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	MLN4924
!smiles	C1CC2=CC=CC=C2C1NC3=NC=NC4=C3C=CN4C5CC(C(C5)O)COS(=O)(=O)N
!pubchem_cid	73014187
!cell_type	A375 melanoma cell line - 2 Hours
!organism	human
!end_metadata
HMOX1	0.226365
CTGF	0.159717
TXNRD1	0.157861
PRDX1	0.128542
FTL	0.123535
DUSP6	0.119798
SGK1	0.098623
FTH1P5	0.095608
PCNA	0.093998
MIR21	0.093609
SRXN1	0.091140
ERRFI1	0.085980
GCLM	0.084935
NQO1	0.080938
SLC7A11	0.080735
PMAIP1	0.080490
CEBPB	0.072498
HSPA8	0.071972
DPM1	0.068772
ORC6	0.065952
HSP90AB1	0.061749
GARS	0.060435
FTH1	0.058985
HSPA1A	0.055139
HLA-DRB1	0.054216
PSMA1	0.052966
OVOS2	0.052059
DUSP4	0.051782
PSAT1	0.051498
UBE2C	0.051383
FBXO30	0.051354
RPLP0	0.050903
PTGES3	0.050506
TRIM16	0.050456
HOXB2	0.047993
PPP1CC	0.047769
DEK	0.047742
ATOX1	0.047671
NOP58	0.047652
RRM2	0.046828
ATF4	0.044814
CAV1	0.044778
KPNA2	0.044722
SLBP	0.044557
UBE2E3	0.044548
DDIT4	0.044342
UHRF1	0.044026
IGF2BP3	0.043963
SNRPB2	0.043221
HINT1	0.041932
HMGN2	0.041827
RPL41	0.041787
FEN1	0.041521
MAT2A	0.041188
NAA50	0.041023
SUMO2	0.040910
PRNP	0.039827
GGH	0.038807
MDH2	0.038634
RPS2	0.038392
LDHA	0.038315
AMIGO2	0.037584
PPA1	0.037182
SNX5	0.036535
BAG3	0.036165
CXCL1	0.036038
SDCBP	0.035390
CXCL8	0.034828
RPL36	0.034757
MAGEA3	0.034731
MT1HL1	0.034667
SLC25A3	0.034385
STK17A	0.033647
NARS	0.033583
USP1	0.033417
CPOX	0.033392
MLLT11	0.033377
WDR82	0.033043
ERH	0.032976
RPL30	0.032970
RPS17	0.032892
MAGEA12	0.032359
CDK1	0.032184
HHEX	0.031865
RPL8	0.031843
MAPK6	0.031811
UHRF2	0.031419
ENOPH1	0.031331
MAGOH	0.030860
RPL3	0.030599
RPS13	0.030479
NSUN2	0.030419
NOP10	0.030193
PSMA6	0.030145
SLC38A2	0.030110
ZNF367	0.030007
HSPA5	0.029918
PABPC3	0.029890
RPS25	0.029885
NPTN	0.029772
S100A10	0.029583
MRPS30	0.029419
C12orf75	0.029340
LBR	0.029022
KIF11	0.028523
SRP14	0.028318
AKR1B1	0.028285
COX7C	0.028246
NCL	0.027965
WNT5A	0.027964
ALYREF	0.027943
ADM	0.027060
NUF2	0.027042
POPDC3	0.027032
TXN	0.026978
SMNDC1	0.026792
ZNF217	0.026766
SMURF2	0.026742
HLA-DRA	0.026735
MTHFD2	0.026360
TOMM20	0.026251
EIF1	0.026064
PRIM1	0.026027
GADD45A	0.025901
CCNB1	0.025644
MAGEA6	0.025515
NACAP1	0.025285
DUT	0.025209
GDI2	0.024908
RND3	0.024762
HERPUD1	0.024728
GRPEL1	0.024504
RAN	0.024387
TBK1	0.024347
USP53	0.024297
KRTAP2-3	0.024039
TM4SF1	0.023932
PLIN2	0.023747
CYR61	0.023491
DTL	0.023433
NNMT	0.023409
BRIX1	0.023134
EI24	0.023096
RGS2	0.023058
RRS1	0.023022
HSP90AA1	0.023010
STX17-AS1	0.022925
ATP6V1A	0.022905
NPC2	0.022862
MANSC1	0.022854
C6orf62	0.022852
RPL35A	0.022637
ATP5I	0.022567
PTTG1	0.022520
MSN	0.022511
DDX47	0.022511
GRPEL2	0.022480
PGK1	0.022464
EZH2	0.022445
BNIP3	0.022318
PDK1	0.022116
BIRC2	0.022109
POLE3	0.021765
MRPS21	0.021686
PTTG1IP	0.021639
CLK2	0.021556
MAD2L1	0.021507
TRMT11	0.021450
LINC00622	0.021446
PTP4A2	0.021407
RPL23A	0.021286
AK4	0.021246
CCNE2	0.021149
DNAJB4	0.021119
PTS	0.021100
RRM1	0.021014
NONO	0.020741
CCT4	0.020716
MICU2	0.020601
NAP1L1	0.020552
RPS12	0.020526
SLC25A5	0.020462
SNHG1	0.020414
PBK	0.020408
ZCCHC8	0.020362
NUTF2	0.020237
UBA52	0.020211
TFPI2	0.020123
LRRC47	0.019929
SNRPD1	0.019914
MIF	0.019871
MRPL51	0.019717
MRPL15	0.019679
NDUFA1	0.019672
RPS18	0.019576
EIF3M	0.019535
LINC00326	0.019532
ELK3	0.019529
ASF1A	0.019504
NOP56	0.019441
CDC6	0.019381
COMMD8	0.019316
NSA2	0.019300
EIF2B1	0.019252
MTCH2	0.019174
ATP5G1	0.019146
MYC	0.019081
EFTUD2	0.019075
NEIL3	0.019071
SF3B6	0.018983
UFD1L	0.018968
EIF4A3	0.018900
RPL18	0.018893
TMA7	0.018866
TNPO1	0.018826
CEP55	0.018758
PRR11	0.018752
MYL12B	0.018731
TRIB2	0.018681
RPA2	0.018658
PET117	0.018525
TRIB3	0.018407
PSMC6	0.018303
PPIF	0.018291
LOC344887	0.018270
GLRX2	0.018189
TRMT6	0.018142
BUB3	0.018041
CHAC1	0.018024
GHITM	0.017982
ANXA1	0.017968
TLR4	0.017847
IER5	0.017826
FOXD1	0.017779
MRFAP1	0.017761
FAM216A	0.017720
SCOC	0.017632
PNO1	0.017593
NDUFC2	0.017559
ETF1	0.017506
RTN4	0.017447
CCND1	0.017401
DCAF13	0.017334
TALDO1	0.017321
EPB41L4A-AS1	0.017206
STARD7	0.017103
SACS	0.017074
ARL6IP1	0.017010
GLA	0.016981
NUDT15	0.016957
PSMD10	0.016920
NAF1	0.016851
PSMA7	0.016819
RPS23	0.016768
HSPD1	0.016587
EIF6	0.016550
PSMA2	0.016531
DNTTIP2	0.016493
PSMB6	0.016414
TMEM126A	0.016411
GMNN	0.016375
SYPL1	0.016273
FAM83D	0.016160
DBF4	0.016157
KIF14	0.016152
UBE2N	0.016124
PTPLAD1	0.016101
TSC22D1	0.015972
GAPDH	0.015893
NET1	0.015848
TPX2	0.015831
ZFAND5	0.015750
DPYSL2	0.015747
RAD21	0.015711
DAP3	0.015689
CTPS1	0.015684
C16orf72	0.015613
COX8A	0.015549
SMIM15	0.015530
ZWINT	0.015492
TNFRSF21	0.015421
NCAPD3	0.015400
UQCRFS1	0.015375
ANLN	0.015362
DLEU1	0.015283
TUSC1	0.015229
DSTN	0.015202
SLC3A2	0.015121
BCAR3	0.015068
SERBP1	0.015065
TFRC	0.015055
ARPC2	0.015054
ASNS	0.015030
SNRPG	0.015022
MCM6	0.015015
CNIH1	0.014982
COX7A2L	0.014971
TOP2A	0.014831
C11orf58	0.014793
CYC1	0.014783
ITM2B	0.014775
DROSHA	0.014768
PAICS	0.014748
DDX46	0.014721
MTHFD1	0.014663
HMMR	0.014655
VDAC1	0.014643
PLK2	0.014621
HEY1	0.014595