!direction	1
!num_genes	417
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Morphine
!smiles	CN1CCC23C4C1CC5=C2C(=C(C=C5)O)OC3C(C=C4)O
!drugbank_id	DB00295
!pubchem_cid	5288826
!cell_type	Striatum - DBA/2J mice - Acute morphine treatment
!organism	mouse
!end_metadata
PTGDS	0.122258
CRYM	0.086044
HTRA1	0.075799
WIPF3	0.075186
SCG2	0.072653
EGR1	0.068365
SLC2A1	0.065381
STAB2	0.064195
LRRC58	0.061912
RASD2	0.061567
FAM107A	0.061158
RPS29	0.058709
WFS1	0.057717
HSPH1	0.056317
CAMK1G	0.056311
HPCAL4	0.055379
DNAJB1	0.055248
NCDN	0.052917
TRANK1	0.052294
ZBTB16	0.051980
STK32C	0.050709
TSC22D3	0.050135
MFSD2A	0.050028
PXDN	0.047656
SGK1	0.046716
ENO2	0.046426
LOC728392	0.045852
RPLP2	0.045749
MAP2K1	0.043871
MAP2	0.043306
MRFAP1	0.043166
HINT1	0.043151
LAMP5	0.042893
DNAJA1	0.042286
PRICKLE2	0.041869
TSC22D1	0.041821
MCF2L	0.041804
PPP1R1B	0.041720
TRIM32	0.041657
PPTC7	0.041469
FKBP5	0.040742
DTX3	0.040494
ABR	0.039820
EPC2	0.039813
MAGED1	0.039686
RAB5C	0.039464
SPNS2	0.039293
ACTR3B	0.039255
ATP6V1A	0.039228
ASTN1	0.039194
ARC	0.039147
BHLHB9	0.038748
FKBP8	0.038637
CRY2	0.038127
KIAA1211L	0.037789
BZRAP1	0.037623
PER1	0.037561
FOXG1	0.037466
MKL1	0.037360
FAM8A1	0.037070
ELMOD1	0.036988
CTXN1	0.036963
BTBD10	0.036936
CLK1	0.036884
NPY	0.036660
NDUFA6	0.036659
FBXL16	0.036630
SLC25A23	0.036603
DNAJB9	0.036437
VDAC3	0.036412
BAG1	0.036371
SYNPR	0.036355
PTPRN	0.036157
HNRNPH1	0.036145
SMARCC2	0.035880
SF3B1	0.035790
AREL1	0.035754
RPS28	0.035494
CDK5R2	0.035387
LDHB	0.035374
RAPGEF2	0.035329
HSPA8	0.035229
RND2	0.035073
GRINA	0.035057
GJB6	0.035040
GAA	0.035023
HNRNPH2	0.034874
RBBP7	0.034752
CHD3	0.034592
NTS	0.034257
ATP6V1F	0.034247
RPL18A	0.034228
DHRS1	0.034153
FBXL5	0.034001
CARTPT	0.033863
CAMK2B	0.033831
RTN1	0.033785
PKIA	0.033444
NME2	0.033345
LAMP1	0.033105
DRD1	0.033076
PRKCE	0.033073
KLHL2	0.033053
SUCLG1	0.032968
NECAB2	0.032835
INF2	0.032736
RPS11	0.032553
PEBP1	0.032468
TMEM35	0.032220
TRAPPC6B	0.032052
PRPF8	0.031887
PCSK1N	0.031822
LAMTOR3	0.031780
SLC4A10	0.031573
CAMKV	0.031448
MRPS6	0.031414
BAI3	0.031327
HNRNPA2B1	0.031230
MAT2A	0.031134
ATP1A2	0.031124
FABP5	0.030920
EDF1	0.030882
BEX1	0.030801
COX7A2	0.030732
COX5A	0.030638
HDAC5	0.030633
CPNE5	0.030619
GRIK5	0.030552
PHACTR3	0.030363
ARGLU1	0.030296
STMN3	0.030295
CACNA2D3	0.030132
ATP6AP2	0.030095
NEGR1	0.030069
WDR6	0.029958
SRRT	0.029935
TAC1	0.029925
SLC25A33	0.029780
OCIAD2	0.029765
C19orf60	0.029733
DAPK1	0.029649
RAB5A	0.029600
MLC1	0.029496
HNRNPDL	0.029396
TPPP	0.029364
CADPS	0.029201
DEK	0.029124
MAT2B	0.029057
NGFRAP1	0.029035
FKBP3	0.029014
GAD1	0.028938
LRP11	0.028887
SEPP1	0.028869
SUPT5H	0.028868
SNPH	0.028761
DDX1	0.028528
TMX1	0.028421
PSMC3	0.028319
TRO	0.028139
VGF	0.028123
RIN2	0.028115
HSPD1	0.028079
THY1	0.028024
GDA	0.028012
ZCCHC12	0.027997
UBP1	0.027893
KCNA5	0.027849
TMEM185A	0.027842
RPL36AL	0.027830
CHMP2A	0.027658
RASGEF1A	0.027444
NAP1L5	0.027243
DVL1	0.027178
SCN4B	0.027176
SVOP	0.027155
PPP1R13B	0.027131
TTYH1	0.027117
MIEN1	0.027098
CPT1C	0.027062
PAPD5	0.027015
PENK	0.026996
NME1	0.026983
PDCD4	0.026908
SPARCL1	0.026906
ITPR1	0.026795
AP2A1	0.026755
TBCE	0.026734
USP54	0.026728
EP300	0.026527
TMEM130	0.026429
SLC38A2	0.026377
WBP2	0.026367
ARRB1	0.026353
ASPHD2	0.026327
NNAT	0.026326
SWI5	0.026270
GGA2	0.026133
HES5	0.026091
TSPYL2	0.026089
MLYCD	0.025992
AMPH	0.025988
RCAN2	0.025948
NELL2	0.025871
SLC25A4	0.025832
DDX3X	0.025773
SIRT2	0.025725
CCT7	0.025718
NECAP1	0.025707
NDRG1	0.025703
LHFP	0.025656
NDUFB9	0.025597
SYNE1	0.025549
RNF208	0.025540
GPS1	0.025524
ATP6AP1	0.025458
AKAP8L	0.025392
RPS27L	0.025378
GNG7	0.025367
EID2	0.025362
ERH	0.025347
SESN1	0.025316
FAM84A	0.025310
RASL10B	0.025244
CELSR3	0.025242
CCRN4L	0.025233
ZBTB11	0.025213
EZR	0.025203
C1orf95	0.025164
SYNDIG1L	0.025146
HNRNPK	0.025121
SYT4	0.025023
JPH4	0.025018
SLC25A14	0.024993
PSAT1	0.024899
LMO7	0.024835
P4HB	0.024782
C12orf43	0.024770
RNF150	0.024765
PCBP2	0.024755
VEGFB	0.024737
ICE1	0.024733
FAM168B	0.024708
YWHAE	0.024706
PLIN4	0.024687
PDZD2	0.024681
TMEM131	0.024584
SSR3	0.024502
LRRC8A	0.024468
PAPSS1	0.024433
GRB2	0.024342
DDX17	0.024280
ARHGEF3	0.024269
TMEM179	0.024193
CELF5	0.024167
SST	0.024123
AKR1A1	0.024088
UQCRB	0.024033
ATP5B	0.024018
NCKAP1	0.023925
ABHD3	0.023871
GALNT16	0.023871
TSPAN3	0.023739
MAPRE3	0.023724
FADS1	0.023682
FBXW5	0.023645
HIST1H2BI	0.023628
GPR83	0.023571
TUBA1A	0.023557
RAP1GAP	0.023543
ITM2C	0.023501
DHX15	0.023473
RPS7	0.023463
HIGD1A	0.023439
CDC42SE2	0.023435
BAP1	0.023401
MARK3	0.023317
GLUD1	0.023309
GMPR	0.023309
ACHE	0.023267
CS	0.023261
UNC80	0.023260
GOT1	0.023242
DUSP6	0.023228
CETN3	0.023135
SLC3A2	0.023083
PAICS	0.023076
ARPC1A	0.023064
GDE1	0.023064
MEIS2	0.023034
PRKCB	0.023009
TUBB3	0.022969
SNX27	0.022964
GSTM3	0.022932
PYGB	0.022910
CTSS	0.022787
PPP2R5B	0.022742
UBE2E1	0.022696
MAGEE1	0.022656
CDKN1A	0.022621
HNRNPLL	0.022619
LY6H	0.022605
ECI2	0.022595
SAT1	0.022541
FAM216A	0.022484
PANK4	0.022479
COPE	0.022447
SLC35E2B	0.022437
SOWAHA	0.022427
INA	0.022422
H2AFZ	0.022416
SLC7A5	0.022392
GNA11	0.022341
CLDN11	0.022314
PPM1E	0.022274
NGEF	0.022246
TMEM50A	0.022216
EFR3B	0.022180
RANBP9	0.022146
TAGLN3	0.022104
DUSP14	0.022091
NMNAT2	0.022068
PCP4	0.021953
AKAP8	0.021927
SLMO2	0.021919
CTTNBP2	0.021898
NDUFB10	0.021893
CACYBP	0.021865
TESC	0.021846
ELOVL5	0.021819
ACTL6B	0.021787
LPPR4	0.021729
DIO2	0.021709
LYPD4	0.021704
NDUFA2	0.021595
CAMLG	0.021528
CDO1	0.021524
RBM45	0.021504
MED10	0.021498
NDUFS1	0.021431
RGS14	0.021422
DLG3	0.021417
KDM3A	0.021365
GABARAPL1	0.021363
TMCC2	0.021337
ARHGAP44	0.021329
GLUL	0.021320
UBE2N	0.021280
CALN1	0.021268
LAMTOR5	0.021265
SDF2	0.021260
NT5DC3	0.021247
MCFD2	0.021218
USP33	0.021197
CYB561	0.021156
PGAM1	0.021144
SLIRP	0.021144
NDUFB3	0.021054
GALNT18	0.021025
SNX1	0.021015
THAP11	0.021015
BTG1	0.020998
KBTBD2	0.020998
ACO2	0.020996
PHYHD1	0.020930
XPO6	0.020930
UQCRC1	0.020920
CRY1	0.020916
UBQLN4	0.020909
SNCA	0.020901
COL6A1	0.020864
HMGN1	0.020864
MARC2	0.020848
SLC24A3	0.020844
DCTN6	0.020812
MCRS1	0.020795
PDCD6	0.020759
ITPKA	0.020700
USP11	0.020614
EDC4	0.020574
ENSA	0.020521
AMPD3	0.020495
VDAC2	0.020494
TTC9B	0.020366
SHANK3	0.020359
VBP1	0.020349
SAP30L	0.020313
KAZN	0.020267
PCMTD2	0.020262
ABI1	0.020260
ACTR3	0.020242
PBX3	0.020232
SDHB	0.020226
RPL15	0.020142
CNST	0.020140
SRP14	0.020124
ARHGAP35	0.020114
ATP6V0B	0.020101
NFE2L1	0.020092
PNMAL2	0.020082
UBALD1	0.020078
KIAA2018	0.020031
TESK1	0.020018
PSMA2	0.020011
SERPINI1	0.020008
SOD1	0.020005
MCM3AP	0.019995
PKM	0.019995
GRN	0.019988
SERINC1	0.019954
GPX4	0.019940
IP6K2	0.019932
IVNS1ABP	0.019932
RASGRF1	0.019877
SKI	0.019843
AMFR	0.019834
SLC30A9	0.019810
SMAD4	0.019794