!direction	1
!num_genes	291
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Rattus norvegicus
!drug_name	Pioglitazone
!smiles	CCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3
!drugbank_id	DB01132
!pubchem_cid	4829
!cell_type	3 months
!organism	rat
!end_metadata
YWHAE	0.155323
MRFAP1	0.150054
UCHL1	0.147134
DPYSL2	0.134698
HNRNPAB	0.122824
NDUFB11	0.089609
RPL37	0.087474
PTGDS	0.083029
PTPLAD1	0.077999
LRRC58	0.075297
ABI2	0.061675
ITPR1	0.060958
NEFH	0.059897
TSPAN3	0.057496
SYP	0.055974
RPS13	0.055454
SERBP1	0.054286
HTRA1	0.054079
ATP6V1B2	0.053642
VTA1	0.048064
ZNF330	0.047116
GOT1	0.046679
BCAS1	0.046561
SKIL	0.046100
SCN3B	0.045818
GSTA5	0.045626
RHOB	0.045032
COPS6	0.044457
RPS3	0.043986
SLC24A2	0.043854
CHST1	0.042911
GABRB1	0.042908
COX1	0.042755
TMCC2	0.042469
NCDN	0.042171
COPS8	0.041835
TAX1BP1	0.041745
GABRA1	0.040697
NDUFA1	0.040681
ITPKA	0.040643
USMG5	0.040479
YWHAH	0.040446
RCHY1	0.040107
PLS3	0.040074
C3	0.039760
NEFL	0.039745
BAG5	0.039695
TRIM2	0.039676
MICU3	0.039572
PGBD5	0.039565
TSPYL4	0.039425
RPL18	0.039388
HNRNPK	0.038772
STK32C	0.038595
CCDC47	0.037258
ATP6V0D1	0.037240
ENO2	0.037078
SCN1B	0.036692
ATRNL1	0.036577
RPL23	0.036499
CTBP1	0.036132
CLSTN1	0.036093
CNIH2	0.035956
COX4I1	0.035922
VMP1	0.035907
WIPF3	0.035714
TXN	0.034904
GNL3L	0.034608
SARNP	0.034497
GDI1	0.034402
APOD	0.034299
PKM	0.033969
PTPN11	0.033872
BCAT1	0.033804
ATP2B1	0.033801
AMD1	0.033554
CEND1	0.033535
GABRG2	0.033393
RNASEK	0.033327
NME2	0.033066
STMN1	0.032549
SYNJ1	0.032353
SLC12A5	0.032069
UQCRB	0.031953
MRPL3	0.031852
SEPP1	0.031828
GLUL	0.031726
PLK2	0.031493
NELL2	0.031223
CHGB	0.031060
RPS25	0.031043
GOT2	0.030969
TMEM50A	0.030849
NDUFB2	0.030849
TFG	0.030669
CAMK2B	0.030527
NAPA	0.029889
ALDOC	0.029743
FBXL5	0.029735
KANSL2	0.029539
ISCA1	0.029313
COL4A3BP	0.029145
PARK7	0.029111
ITIH3	0.029094
MRPL55	0.029023
COX7B	0.028958
OSTM1	0.028937
RTN1	0.028922
GSTO1	0.028878
ELMOD1	0.028740
TMX4	0.028689
NAPB	0.028574
RPS15A	0.028360
GAA	0.028156
TCF4	0.028138
RPS28	0.027995
PSMB1	0.027988
CAMK2A	0.027921
COMMD3	0.027857
LMBRD1	0.027709
PCP4	0.027612
DYNC1I1	0.027170
SRP14	0.027153
ANKS1B	0.027109
ATP5A1	0.027090
HRAS	0.027030
NDUFB3	0.026990
TRAK1	0.026925
HSPA4	0.026911
SLC38A2	0.026787
PPP3CA	0.026724
BTG1	0.026594
SNN	0.026471
CD74	0.026457
WASF1	0.026353
PICALM	0.026323
WFS1	0.026295
RPS23	0.026244
MAEA	0.026238
ATP5O	0.026153
SCG5	0.026053
WSCD1	0.026046
TTC3	0.026025
CALY	0.025978
SUCLG2	0.025971
RPS10	0.025888
NDUFA2	0.025793
RAB3A	0.025733
ATP5B	0.025690
RPS20	0.025608
DYNLL1	0.025493
CHMP2A	0.025448
TMEM9B	0.025433
VPS29	0.025366
SLC25A4	0.025182
CDC40	0.025176
AP2A2	0.025104
EIF3E	0.024945
SULT4A1	0.024923
ITM2B	0.024818
ARHGAP39	0.024695
NSA2	0.024649
FAM134A	0.024617
SEC62	0.024610
NDUFB6	0.024569
CKB	0.024511
PCNX	0.024432
RPS7	0.024337
BECN1	0.024299
COX8A	0.024293
MEX3B	0.024272
RPL13A	0.024259
PRDX2	0.024120
SUGT1	0.024115
FAHD1	0.024103
USP54	0.024089
B4GALT6	0.024077
DUSP3	0.024077
PAQR8	0.024044
PELI1	0.023892
RPLP0	0.023892
DNAJC27	0.023868
POLR2G	0.023855
WNT4	0.023765
CAB39	0.023754
RYR2	0.023691
ACTR2	0.023681
BIN1	0.023658
CACNA2D1	0.023658
EIF4G3	0.023518
STX1B	0.023413
TUBA4A	0.023388
ALDOA	0.023375
DYNC1H1	0.023312
GRINA	0.023264
MAP1A	0.023241
LRRN2	0.023193
ANXA11	0.023120
TVP23A	0.023072
EID1	0.023006
ROGDI	0.022865
SEPT7	0.022797
BLOC1S1	0.022702
PRRC2A	0.022663
BSN	0.022480
CDK17	0.022440
ARPC3	0.022425
PSMA2	0.022330
TOMM20	0.022237
MAGED1	0.022167
GCC2	0.022129
MAP2K1	0.022080
HIF1A	0.021886
CCNG2	0.021788
ATP2B3	0.021776
NRN1	0.021727
CRMP1	0.021500
TMEM14A	0.021479
PPP3R1	0.021338
TRAPPC6B	0.021313
MRPL32	0.021222
AUH	0.021168
GNAO1	0.021140
UPF2	0.021097
SLC25A12	0.021075
ACTN4	0.021032
RPL18A	0.021031
VCP	0.020897
ABRACL	0.020880
ATP6V1A	0.020849
STUB1	0.020766
ARPC2	0.020738
WSB1	0.020663
ATP1A1	0.020662
UQCR10	0.020645
PLEKHG5	0.020627
C11orf73	0.020574
TUBB4A	0.020555
CX3CL1	0.020533
SH3BP5	0.020474
PCSK1N	0.020460
SPHKAP	0.020460
CPEB4	0.020338
SUMO3	0.020223
CSRP1	0.020214
COX7A2	0.020126
RABAC1	0.020069
MFSD6	0.020056
ZMYND8	0.019971
NDUFS7	0.019935
CDK5	0.019927
VGF	0.019914
PSMB2	0.019911
RASGRP1	0.019909
GAPDH	0.019894
CHGA	0.019863
WNT1	0.019798
PTP4A3	0.019586
GRIA2	0.019514
APBB1	0.019460
VDAC1	0.019397
NTRK2	0.019396
RTCB	0.019387
LARP4B	0.019273
PRICKLE2	0.019213
SMAP1	0.019203
EMB	0.019192
GPC4	0.019188
LDHB	0.019152
SPRY2	0.019098
LDHA	0.019078
SLC30A3	0.019053
GRN	0.019028
ID3	0.018992
VPS28	0.018981
DLGAP1	0.018911
EIF5	0.018888
STRN3	0.018821
PSMB7	0.018817
WDR37	0.018771
SNRPA1	0.018645
DCAF12	0.018539
NPC2	0.018517
ACSL3	0.018514
TNFAIP1	0.018487
MIEN1	0.018439
ATP5J2	0.018315
R3HDM1	0.018240
SEPT4	0.018194
TPT1	0.018171
ARPC1A	0.018132