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| Title / Description | Ovarian cancer xenograft tumor response to trastuzumab and pertuzumab |
| Accession | GDS4814 |
| Summary | Analysis of SKOV3 ovarian cancer xenograft tumors treated with trastuzumab (TZ), pertuzumab (PZ), or both. TZ and PZ target Human Epidermal Growth Factor Receptor 2 (HER2). Combined therapy results in enhanced antitumor activity. Results provide insight into the molecular basis of this enhancement. |
| Organism | Homo sapiens |
| Platform | GPL6947 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell | Ovary |
| Perturbation | Pertuzumab |
| Disease | Ovarian cancer xenograft tumor |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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| Combined |
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