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| Title / Description | Bacterial cell wall component MDP effect on HEK293 cells expressing Crohn's disease-associated NOD2 variant L1007fsinsC receptor: time course |
| Accession | GDS4416 |
| Summary | Temporal analysis of HEK293 cells stably-expressing wildtype NOD2 receptor or variant NOD2L1007fsinsC and treated with muramyl dipeptide (MDP). MDP-induced NOD2 activation induces inflammatory and antibacterial factors. Results provide insight into molecular basis of NOD2-mediated immune response. |
| Organism | Homo sapiens |
| Platform | GPL570 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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