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| Title / Description | Premature Hematopoietic Aging model: bone marrow hematopoietic stem cells |
| Accession | GSE27686 |
| Summary | Analysis of hematopoietic stem cells (HSCs) from mid-aged mutator females that express a proofreading-defective form of the mitochondrial DNA polymerase gamma (POLG). Results provide insight into the molecular mechanisms underlying multiple aspects of aging accelerated in the mutator model. |
| Organism | Mus musculus |
| Platform | GPL1261 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell | Hematopoietic stem cells |
| Perturbation | Aging |
| Young | 2-3 |
| Old | 6 |
| Time unit | Months |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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