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GEN3VA Reports for these tags

AGING_BD2K_LINCS_DCIC_COURSERA AG

SOFT file
Title / Description Age-related gene expression changes in mouse neocortex
Accession GSE13120
Summary Aging is associated with major nuclear changes affecting genomic integrity and gene expression. Here we compare the gene expression profiles in the neocortex of young (5 months old) and old (30 months old) B6xC3 F1 mice. In a related study, we compare genes that change expression with age to SIRT1 associated genes identified by ChIP on chip (NimbleGen) and find a significant overlap, indicating that SIRT1 target genes are preferentially deregulated with age. Keywords: gene expression comparison, age-comparison
Organism Mus musculus
Platform GPL1261
Normalized False
Parsed SOFT file
Metadata
Differential expression method Characteristic Direction
Cutoff 500
Organism Mus musculus
Old 30
Young 5
Cell_type neocortex
Age_unit month
Organism Mus musculus
Cell Brain
External Links and Downloads
Gene lists Enrichr L1000CDS2 PAEA Crowdsourcing
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