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| Title / Description | FGFR signature |
| Accession | GSE73024 |
| Summary | Drugs that target specific gene alterations have proven beneficial in the treatment of cancer. Because cancer cells have multiple resistance mechanisms, it is important to understand the downstream pathways of the target genes and monitor the pharmacodynamic markers associated with therapeutic efficacy. We performed a transcriptome analysis to characterize the response of various cancer cell lines. |
| Organism | Homo sapiens |
| Platform | GPL570 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell | Lung (NCIH520) |
| Perturbation | CH5183284 (FGFR inhibitor) 1uM for 24hrs |
| Disease | Relevant info: Transcriptome analysis of control (DMSO) vs CH5183284 |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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