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| Title / Description | Celecoxib induced transcriptional alterations in gastric cancer cells |
| Accession | GSE54657 |
| Summary | Celecoxib is recognized to have chemopreventive and anti-cancer property beyond its anti-inflammatory function. Celelcoxib treatment in AGS cells down regulates Wnt/β-catenin, STAT3, RXR and ERK/MAPK signaling pathways. Transcriptional profiling after celecoxib shows differential regulation of oncogenic pathway regulated genes. |
| Organism | Homo sapiens |
| Platform | GPL6244 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Organism | Homo sapiens |
| Cell | gastric cancer |
| Perturbation | celecoxib |
| Concentration | 20 uM |
| Time | 24 hrs |
| Disease | gastric cancer |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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