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| Title / Description | Rosiglitazone effect on streptozotocin-induced diabetic DBA/2J mice: perpheral sciatic nerve |
| Accession | GSE11343 |
| Summary | Analysis of sciatic nerve of STZ-induced diabetic DBA/2J mice treated with Rosi, a potent insulin sensitizer. Diabetic DBA/2J mice developed severe hyperglycemia, diabetic neuropathy (DN), and elevated oxidative stress. Results provide insight into the effect of Rosi treatment on DN development. |
| Organism | Mus musculus |
| Platform | GPL1261 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Drug_name | Rosiglitazone |
| Smiles | O=C1NC(=O)C(S1)Cc1ccc(cc1)OCCN(c1ccccn1)C |
| Drugbank_id | DB00412 |
| Cell_type | diabetes |
| Organism | mouse |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | Crowdsourcing | |
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