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| Title / Description | Type 1 diabetes model response to cyclophosphamide: time course |
| Accession | GSE2254 |
| Summary | Analysis of pancreatic islets from BDC2.5/NOD transgenics after treatment with 200 mg/kg cyclophosphamide (CY) at various time points up to 3 days. CY induces diabetes in BDC2.5/NOD transgenics. Results provide insight into molecular events accompanying the progression from insulitis to diabetes. |
| Organism | Mus musculus |
| Platform | GPL81 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Drug_name | Cyclophosphamide |
| Smiles | C1CNP(=O)(OC1)N(CCCl)CCCl |
| Drugbank_id | DB00531 |
| Pubchem_cid | 2907 |
| Cell_type | Pancreatic islets (from BDC2.5/NOD transgenics) - 200 mg/kg -1 Day after treatment |
| Organism | mouse |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | Crowdsourcing | |
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