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| Title / Description | All-trans-retinoic acid effect on transglutaminase 2-silenced, NB4 model of acute promyelocytic leukemia: time course |
| Accession | GSE23702 |
| Summary | Analysis of stable TG2-knockdown NB4 APL cells induced to differentiate in the presence of all-trans-retinoic acid (ATRA) for up to 72 hrs. Silencing of TG2 delays the differentiation process of NB4 cells. Results provide insight into the role of TG2 in the ATRA-induced differentiation of NB4 cells. |
| Organism | Homo sapiens |
| Platform | GPL6244 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Drug_name | Tretinoin |
| Smiles | CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C |
| Drugbank_id | DB00755 |
| Pubchem_cid | 444795 |
| Cell_type | NB4 APL 9 - acute promyelocytic leukemia cells - (TG2-knockdown) 48 Hours |
| Organism | human |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | Crowdsourcing | |
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