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| Title / Description | Synthetic androgen R1881 effect on transcription factor SRF-deficient prostate cancer cells |
| Accession | GSE22606 |
| Summary | Analysis of LNCaP androgen-sensitive prostate adenocarcinoma cells, SRF (serum response factor)-silenced and treated with synthetic androgen R1881. Effects of androgens on prostate cancer (PCa) cells can be mediated by SRF. Results provide insight into targets for androgen action in PCa cells. |
| Organism | Homo sapiens |
| Platform | GPL570 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Drug_name | R1881 |
| Smiles | CC1(CCC2C1(C=CC3=C4CCC(=O)C=C4CCC23)C)O |
| Pubchem_cid | 13766 |
| Cell_type | SRF Silenced cells |
| Organism | human |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | Crowdsourcing | |
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