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GEN3VA Reports for these tags

DRUGS_BD2K_LINCS_DCIC_COURSERA

SOFT file
Title / Description Oncogenic BRAF harboring melanoma cell line response to BRAF inhibition
Accession GSE42872
Summary Analysis of A375 melanoma cells harboring the BRAF V600E oncogenic mutation following treatment with the BRAF inhibitor vemurafenib. Results provide insight into the role of the BRAF V600E oncogene in the pathogenesis of melanoma.
Organism Homo sapiens
Platform GPL6244
Normalized False
Parsed SOFT file
Metadata
Differential expression method Characteristic Direction
Cutoff 500
Drug_name vemurafenib
Smiles CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)C4=CC=C(C=C4)Cl)F
Pubchem_cid 42611257
Cell_type BRAFV600E A375 human melanoma cells
Organism human
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Gene lists Enrichr L1000CDS2 PAEA Crowdsourcing
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