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| Title / Description | Acetaminophen effect on thioredoxin reductase 1-null liver |
| Accession | GSE37874 |
| Summary | Analysis of liver from hepatocyte-specific, thioredoxin reductase 1 (TrxR1)-null mutants treated with the pro-toxin acetaminophen. The Trx system impacts bioenergetics and drug metabolism. Results provide insight into the role of the Trx system in detoxifying certain xenobiotic challenges. |
| Organism | Mus musculus |
| Platform | GPL8321 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Drug_name | Acetaminophen |
| Smiles | CC(=O)NC1=CC=C(C=C1)O |
| Drugbank_id | DB00316 |
| Pubchem_cid | 1983 |
| Cell_type | No Data |
| Organism | mouse |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | Crowdsourcing | |
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