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| Title / Description | BRCA1/CtIP/ZBRK1 repressor complex depletion effect on mammary epithelial cells |
| Accession | GDS2189 |
| Summary | Analysis of MCF10A mammary epithelial cells (MECs) in 3D culture following depletion of the BRCA1/CtIP/ZBRK1 repressor complex using BRCA1 or CtIP RNAi. Results provide insight into the molecular mechanisms underlying the accelerated mammary tumor growth correlated with impaired BRCA1 function. |
| Organism | Homo sapiens |
| Platform | GPL570 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Organism | Homo sapiens |
| Cell | MCF10A |
| Perturbation | depletion |
| Gene | BRCA1 |
| Entrez gene | 672 |
| Disease | Breast cancer |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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