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| Title / Description | Alpha-synuclein deficiency effect on striatum and cerebellum: time course |
| Accession | GDS4153 |
| Summary | Analysis of striatum and cerebellum from alpha-synuclein (SNCA) knockouts at 6 or 21 months of age. SNCA mutations result in impaired movement and depression/anxiety, manifesting in humans as Parkinson's disease (PD). Results provide molecular insights into physiological role of alpha-synuclein. |
| Organism | Mus musculus |
| Platform | GPL1261 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell | Brain |
| Perturbation | Aging |
| Cell esp | Striatum |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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