This is a permanent results page for your analyzed data. Please save the link in your browser's address bar.
| Title / Description | H9 hESC-derived neural stem cells harboring pathogenic leucine-rich repeat kinase 2 mutation |
| Accession | GDS4401 |
| Summary | Analysis of LRRK2 (Gly2019Ser) mutant neural stem cells (NSC) treated with LRRK2 kinase specific inhibitor LRRK2-IN-1. The LRRK2 (G2019S) mutation causes familial Parkinson's disease. Results provide insight into molecular basis of progressive degeneration of NSCs caused by pathogenic LRRK2. |
| Organism | Homo sapiens |
| Platform | GPL571 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell | Neural stem cells |
| Perturbation | PD heterozygous LRRK2 mutation - LRRK2 inhibitor |
| Disease | Parkinson's Disease |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
| Up |
|
|||
| Down |
|
|||
| Combined |
|
|
|
