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| Title / Description | Co-expression of tyrosine kinase receptors HER2 and HER3 in mammary epithelial cells MCF10A grown in three-dimensional cultures |
| Accession | GDS4359 |
| Summary | Analysis of MCF10A mammary epithelial cells expressing HER2, HER3, or HER2/HER3 heterodimer. Co-expression of HER2 and HER3 induced migration and invasion of MCF10A cells. Results provide insight into the role of HER2 and HER3 in breast cancer. |
| Organism | Homo sapiens |
| Platform | GPL6244 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Organism | Homo sapiens |
| Cell | MCF10A |
| Perturbation | coexpression |
| Gene 1 | ERBB2 (HER2) |
| Gene 2 | ERBB3 (HER3) |
| Entrez gene 1 | 2064 |
| Entrez gene 2 | 2065 |
| Disease | Breast cancer |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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