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| Title / Description | TRIF-deficient Herpes simplex encephalitis patient: fibroblast response to interleukin-1β and TLR3 agonist poly (I:C) |
| Accession | GDS4539 |
| Summary | Analysis of SV40 skin fibroblasts collected from an HSV1 encephalitis (HSE) patient with TRIF deficiency (homozygous TRIF nonsense mutation) and stimulated with IL-1β or poly I:C . TRIF is the sole adaptor protein for TLR3. Results provide insight into the role of the TLR3 pathway in HSE. |
| Organism | Homo sapiens |
| Platform | GPL10558 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Ligand_name | interleukin-1β |
| Ligand_id | 3553 |
| Cell_type | fibroblast |
| Organism | human |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | Crowdsourcing | |
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